35 results about "Kidney stone disease" patented technology

The invention discloses a special-disease calculus-removing decoction for treating renal calculus, relates to a traditional Chinese medicine composition, and belongs to the traditional Chinese medicine field. The invention is characterized in that the raw material herbs comprise: grifola, rhizoma alismatis, poria cocos, radix astragali, plantain seeds, dianthus superbus, semen abutili, semen lepidii, combined spicebush roots, radix cyathulae, white peony roots, corydalis tuber, talcum powder, verbena, cornu cervi degelatinatum, desmodium, lygodium japonicum, chicken gizzard membrane (taken after mixing it with water), donkey-hide gelatin (molten by heat), stir-baked squama manitis (taken after mixing it with water), cinnamon, processed monkshood (fried firstly), fructus amomi, rhizoma zingiberis, and licorice. The beneficial effects are that the decoction adopts traditional Chinese medicine theory, and has significant rapid efficacy of dissolving calculus, removing calculus, and expelling calculus; the decoction is economical, cheap, high-efficient, simple, practical, and easy to accept by patients, and is an advanced traditional Chinese medicine therapy for treating urinary system calculus diseases.

A Chinese medicine in the form of particles for treating nephrolithiasis and the lithiasis in urinary system is prepared from 11 Chinese-medicinal materials including lygodium spores, corydalis tuber, earthworm, cinnamon bark, etc through proportional mixing, pulverizing, immersing, seeping, decocting, filtering, depositing, concentrating, granulating and drying.

The invention relates to Chinese medicinal decoction used for treating lithiasis and a preparation method thereof, and relates to Chinese medicinal decoction for treating biliary calculus and renal calculus diseases. Main components of the decoction comprise ophiorrhiza pumila, dandelion, rhizoma sparganii, zedoary, white paeony root, herba pyrrosiae, bupleurum, Szechuan lovage rhizome, peach kernel, radix curcumae, gizzard lining, curcuma, knotgrass, gardenia, dried old orange peel, immature tangerine peel, liquorice and the like. The Chinese medicinal decoction can effectively heal intrahepatic bile duct calculus after the gall bladder is extirpated and calcification and sand-like calculus in the kidney, and simultaneously can effectively promote choleresis, improve the self-healing function of the gall bladder, and recover the functions of the gall bladder and the kidney.

The invention discloses an application of elaeagnus conferta roxb, namely the application of the elaeagnus conferta roxb in preparation of drugs for treating kidney stones, gall-stone and hyperuricemia. In the treatment of the kidney stones, the drug is used for reducing the rate of the kidney stones, improving kidney coefficient, reducing calcium content of the kidney, reducing serum urea nitrogen and reducing serum creatinine. In the treatment of the gall-stone, the elaeagnus conferta roxb is used for treating bile pigment gallstones and cholesterol gallstones; preferably in the treatment of bilirubin gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones, calcium ion content in bile, total bilirubin concentration and free bilirubin concentration in the treatment of the bile pigment gallstones; in the treatment of the cholesterol gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones and the cholesterol content in the bile; and in the treatment of hyperuricemia, the elaeagnus conferta roxb is used for reducing uric acid content in serum. The application of the elaeagnus conferta roxb can be spread to related products of the elaeagnus conferta roxb; and the related product includes a fruit aqueous extract of the elaeagnus conferta roxb, dewatered elaeagnus conferta roxb, capsules, troches, granulas, fruit vinegar, jam and fruit juice.

The traditional Chinese medicine composition for kidney calculi, which comprises the following components in parts by weight: 5-10g of nutrition, 10-15g of Prunella vulgaris, 5-10g of heracleum lanatum, 10 -15g of Plantago lanceolata, 5-10g of red peony, 5-10g of licorice, 10-15g of lycium barbarum, 10-15g of schisandra, 10-15g of herba lysimachiae, 10-15g of poria peel, 5-10g of epimedium, 10-15g of dodder seed, 10-15g of saururus, 5-10g of astragalus and 5-10g of earthworm. The traditional Chinese medicine composition has the advantages of good curative effect, wide medicament sources and no side effects, and is easy to prepare.

The invention relates to a traditional Chinese medicine formula for treating kidney stone, which is characterized by comprising the following components according to parts by weight: 50-60 parts of longhairy antenoron herb, 30-40 parts of lygodium japonicum, 25-30 parts of semen cuscutae, 15-20 parts of polygonum aviculare, 10-15 parts of dianthus superbus radix rehmanniae, 10-15 parts of ural licorice root tip, 10-15 parts of endothelium corneum gigeriae galli, 8-12 parts of salted semen plantaginis, 8-10 parts of polygonum multiflorum and 8-10 parts of radix achyranthis bidentatae. The traditional Chinese medicine formula is simple and convenient in composition, easy to take, low in cost, and light in pain of patients, not only has components for removing urinary calculus and melting urinary calculus, but also has components for tonifying kidney, can carry out effective health care on the kidney of patients while being used for treating patients with kidney stone so that the damaged kidney of the patient can recover to be healthy as early as possible, and is quick in treatment effect and high in cure rate.

The invention discloses a traditional Chinese medicine mixture for removing urinary calculus and a preparation method thereof. The mixture is prepared from, by weight, 16 g of herba pyrrosiae, 20 g of fried endothelium corneum gigeriae galli, 12 g of lysimachia christinae hance, 10 g of radix rehmanniae, 12 g of chingma abutilon seeds, 6 g of akebiaquinata, 10 g of peach kernels, 10 g of poria cocos, 10 g of radix achyranthis bidentatae, 16 g of raw liquorice, 12 g of talc, 12 g of lygodium japonicum, 10 g of rhizoma alismatis, 10 g of lalang grass rhizome, 6 g of radix scutellariae, 6 g of radix linderae and 9 g of cortex moutan. The traditional Chinese medicine composition is scientific and reasonable in formula, novel and reasonable in preparation method, high in process parameter precision, less in component loss and stable in medicine effect, is suitable for various urinary calculus diseases such as kidney calculus and urethral calculus, is not easy to relapse after being cured, and meets clinical treatment requirements.

The invention relates to a Chinese herbal medicine for treating renal calculi. The Chinese herbal medicine for treating the renal calculi is prepared from 3-10 parts of rhizoma corydalis, 3-10 parts of curcuma aromatica, 5-15 parts of trogopterus dung, 15-30 parts of christina loosestrife herb, 6-15 parts of lygodium japonicum, 3-12 parts of endothelium corneum gigeriae galli, 9-18 parts of polygonum aviculare, 9-18 parts of pink herb, 6-12 parts of pyrrosia lingua, 9-18 parts of semen plantaginis, 10-15 parts of salviae miltiorrhizae, 6-12 parts of turtle shell, 5-15 parts of oyster, 5-15 parts of lalang grass rhizome, 5-12 parts of achyranthes root, 6-10 parts of eucommia bark and one fresh pig kidney. The invention also provides a preparation method of the Chinese herbal medicine for treating the renal calculi. The Chinese herbal medicine for treating the renal calculi has the effects of resolving stones, removing urinary calculus, replenishing renal qi, enhancing qi transformation function of urinary bladder, inducing diuresis for treating stranguria, resolving hard lumps, clearing away heat and toxic materials as well as resolving tetany and relieving pain.

The invention relates to brick tea for preventing and treating a kidney stone disease and a preparation method of the brick tea, which belong to the technical field of brick tea health-care food. The brick tea comprises the following raw materials in parts by weight: 90-100 parts of raw dark green tea, 5-18 parts of rhizoma alismatis, 20-27 parts of honey, 9-15 parts of semen plantaginis, 11-19 parts of lygodium japonicum, 5-10 parts of rhizoma phragmitis and 9-20 parts of liquorice. Ingredients and proportions of the brick tea for preventing and treating the kidney stone disease provided by the invention are matched, and the brick tea can be used for recuperating patients suffering from the kidney stone disease, does not cause electrolyte disturbance of the patients, is good in taste and has small side effects; and by virtue of the honey, not only can the taste of the brick tea be improved, but also effects of eliminating toxin and beautifying skin are achieved, and the fungus growing of the brick tea is easier in a preparation process.

The invention relates to the field of traditional Chinese medicines, in particular to a tea bag as well as a preparation method and an application method thereof. The tea bag at least comprises the following components in parts by weight: 2 parts of erythropalum scandens, 2 parts of herb of spicate clerodendranthus, 2 parts of gynostemma pentaphylla, 1.5 parts of radix puerariae, 1 part of lysimachia christinae hance, eucommia ulmoides and 1 part of cichorium intybus. The tea bag disclosed by the invention is a herbal tea bag, has multiple effects of regulating and treating hyperuricemia and concurrent diseases thereof in virtue of one dosage of the tea bag, adopts pure natural raw materials, and is good in curative effect, quick in effect, free of toxic and side effects and capable of regulating and treating gout, diabetes mellitus and concurrent diseases caused by gout and diabetes mellitus, e.g., hypertension, hyperlipidemia, hyperglycemia, hyperuricemia, gallstone, kidney stone, bladder stone, ureteral stone, urethral stone, cholecystitis, hepatitis, nephritis, cystitis, urethritis and adenitis; the tea bag is mixed with water and taken once in the morning, at noon and at night, respectively; and 100 bags are continuously taken for a course of treatment until symptoms completely disappear, irritant food such as seafood, beer and animal viscera is forbidden during taking ofthe tea bag, and people with serious symptoms can take the tea bag for 3-4 courses of treatment.

The present invention provides the application of carbonic anhydrase-2 as a detection marker in the diagnosis of kidney stones, and relates to the field of biomedical diagnosis, specifically the application of carbonic anhydrase-2 as a detection marker in the diagnosis of kidney stones. By detecting carbonic anhydrase ‑2 content and activity to diagnose kidney stones, carbonic anhydrase ‑2 includes multiple species and subtypes, has a high degree of homology, and detection of different species and subtypes can often achieve the same effect. The present invention has verified that urine Liquid carbonic anhydrase-2 was significantly elevated in patients with kidney stones, which can clearly distinguish healthy people from patients with renal tumors. At the same time, the diagnostic value of urine carbonic anhydrase-2 in the detection of kidney stone patients was further verified. It has the advantages of high diagnostic sensitivity and specificity, and convenient detection. , It is convenient for clinicians to give corresponding prevention and treatment measures, which reduces the economic burden and physical pain of patients.

The invention belongs to the technical field of traditional Chinese medicine research and development, and particularly relates to a traditional Chinese medicine preparation for treating kidney calculi. The traditional Chinese medicine preparation for treating the kidney calculi is prepared from, by weight, 9-21 parts of Chinese yams, 15-30 parts of poria cocos, 9-20 parts of rhizoma alismatis, 18-25 parts of endoconcha sepiae, 15-25 parts of natrii sulfas, 10-18 parts of herba plantaginis, 3-11 parts of nigella glandulifera freyn, 25-35 parts of herb of tropic ageratum, 10-19 parts of pomegranate roots, 6-10 parts of stems and leaves of assan crotalaria, 10-20 parts of cortex eucommiae and 3-12 parts of radix angelicae dahuricae. The traditional Chinese medicine preparation for treating the kidney calculi is small in toxic and side effects, significant in curative effect, capable of treating both symptoms and root causes and low in relapse rate after healing; according to the traditional Chinese medicine preparation for treating the kidney calculi, the preparation method is simple, low in cost, easy to implement and easy to apply and popularize.

The invention discloses a traditional Chinese medicine mixture for removing urinary calculus and a preparation method thereof. The mixture is prepared from following raw materials in parts by weight, 16 g of herba pyrrosiae, 16 g of radix rehmanniae, 12 g of chingma abutilon seeds, 10 g of poria cocos, 6 g of raw liquorice, 12 g of lygodium japonicum, 20 g of fried endothelium corneum gigeriae galli, 6 g of radix scutellariae, 12 g of talc, 10 g of rhizoma alismatis, 10 g of polyporus umbellatus, 9 g of plantain herb, 15 g of herba patriniae, 10 g of lalang grass rhizome, 20 g of lysimachia christinae hance and 10 g of gardenia jasminoides. The traditional Chinese medicine composition is scientific and reasonable in formula, novel and reasonable in preparation method, high precision of process parameter, less in component loss and stable in medicine effect. The traditional Chinese medicine composition is suitable for various urinary calculus diseases such as kidney calculus and urethral calculus, is not easy to relapse after being cured, and meets clinical treatment requirements.

The invention belongs to the field of traditional Chinese medicines, in particular discloses a traditional Chinese medicine for treating renal calculus, which comprises raw rehmannia root, chaff flower root, common macrocarpium fruit, white paeony root, yanhusuo, liquorice root, artemisia capillaries, chicken's gizzard-membrane, pink herb, Indian buead, radix scrophulariae, ludwizia prostrata roxb., polygonum capitatum and plantain herb serving as raw materials in a certain weight part ratio. The traditional Chinese medicine has the advantages of simple preparation, good absorption effect, obvious curative effect, no side effect, high safety, and contribution to relieving symptoms of diseases in time.

The invention relates to the technical field of tea, and discloses tea for treating gallstone, kidney stone and urethral stone. The tea is prepared from the following components in parts by mass: 5 to 8g of Orthosipon aristatus, 1 to 2g of pericarpium citri reticulatae, 0.5 to 1.0 g of liquorice root, 0.5 to 1.0 g of honeysuckle flower and 0.5 to 1.0 g of chrysanthemum flower. The tea for treating gallstone, kidney stone and urethral stone can solve the problems that at present, calculus is mainly treated through an operation or medicine, the operation is mainly used for treating diseases, a patient suffers from great pain, and symptoms are treated but not root causes are treated.

The invention discloses a traditional Chinese medicine decoction for treating renal calculus and a preparation method thereof. The decoction is prepared by decocting the following components together: achyranthes root, desmodium, pangolin, clerodendranthus spicatus, plantain, dwarf lilyturf tuber, radix astragali, cordate houttuynia, spatholobus stem, spiranthes sinensis, ginger, wolfberry, and ligusticum wallichii. The decoction is developed to generate functions of activating blood circulation to remove stasis, freeing collaterals, relieving pains, and tonifying kidney and liver; the components in the decoction can cooperate with each other to generate a synergetic effect; and the decoction mainly has the functions of activating blood circulation to remove stasis, freeing collaterals, relieving pains, nourishing blood and yin, reinforcing the organism immunity, tonifying vitality, modulating the internal organs, can fully modulate and improve the functions of human body, and has a prominent curative effect on renal calculus. The provided traditional Chinese medicine decoction has the advantages of simple preparation, good absorption effect, long-lasting efficacy, prominent curative effect, no side effect, high safety, and low production cost, can relieve the symptom of patients in time, and is capable of eliminating the root of disease so as to cure renal calculus radically.

The invention discloses traditional Chinese medicine medicinal liquor and a preparation method thereof. The traditional Chinese medicine medicinal liquor is prepared from the following raw materials: 20 to 25g of herba centellae, 20 to 25g of radix angelicae pubescentis, 20 to 25g of radix sileris, 15 to 20g of herb of snakehead grass, 15 to 20g of herba pennisetum yunnanense, 15 to 20g of semen strychni, 10 to 20g of white mulberry leaves, 10 to 20g of rhizoma paridis chinensis and 1000g of white spirit of 40 to 45 degrees. The traditional Chinese medicine liquor can effectively prevent or treat epidemic severe cold, qi fullness and stuffiness, enteritis, gall stone, kidney stone, urethral calculus, psoriasis, beriberi, age pigment, three-high diseases, cerebral thrombosis, hemiplegia, limp, numb and swelling of all parts of a body and internal organs diseases.

The present invention relates to nutritional honey extension slurry for treating kidney stones. The honey extension slurry is prepared from the following raw materials in parts by weight: 270-285 parts of honey, 14-17 parts of rhizoma imperatae, 1-3 parts of loofah sponges, 12-16 parts of chicken's gizzard-membrane, 13-16 parts of poria cocos, 28-33 parts of coix seeds, 8-10 parts of common lophatherum herb, 14-18 parts of reed rhizomes, 3-6 parts of glossy privet fruits, 7-11 parts of Chinese magnoliavine fruits, 3-7 parts of dried tangerine peels, 12-15 parts of common cephalanoplos herb, 8-11 parts of peach kernels, 2-4 parts of fresh gingers, 3-5 parts of licorice, 1-3 parts of lemons, 10-20 parts of parslane herb and 2-4 parts of haws. The honey extension slurry has functions of foodin tonifying health and treating diseases, is suitable for downward flow of damp-heat, qi-stagnation and blood stasis of urolithiasis, and safe and free of toxic side effects, can be used for treatingdiseases of urethral calculus, urolithiasis or gallstones, etc., and also has good curative effects on frequent urination, urgent urination and hematuria. The honey extension slurry has effects on cooling blood, stopping bleeding, clearing heat, causing diuresis, softening hard mass, relieving, removing and dispelling stones, relieving stranguria by diuresis, strengthening kidneys, benefiting essence, strengthening yang and securing essence, and is a nutritional type medicinally and edibly homogenous product.

The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for treating gall and kidney stones. The medicine for treating gall and kidney stones comprises the following ingredients in parts by weight: 0.5-1 part of pseudosciaena crocea, 0.5-1 part of prepared salt, 1-3 parts of radix rhei, 1-3 parts of Cudrania cochin chinensis (Lour.) Kudo et Masam.Roots, 1-3 parts of folium pyrrosiae, 1-3 parts of spora lygodii, 1-3 parts of talcum, 1-3 parts of pumice stones, 1-3 parts of rhizoma sparganii, 1-3 parts of rhizoma curcumae, 2-4 parts of endothelium ccorneum gigeriae galli, 2-4 parts of radix astragali and 5-7 parts of herba lysimachiae. The medicine for treating gall and kidney stones has reasonable compatibility of medicines, conforms to aprinciple of "assistant and guide", conforms to gall, kidney and urinary bladder stone pathogenesis, has the efficacy of benefiting the gall, removing stones, detoxifying, resisting inflammation, promoting qi circulation and removing obstruction, and is suitable for various patients of gall, kidney and urinary bladder stones.

The invention discloses an externally applied prescription and an externally applied patch thereof. The externally applied patch is prepared from the following raw materials in parts by weight: 20-40parts of scorpio, 20-40 parts of leeches, 40-60 parts of dragon's blood, 20-40 parts of ground beetles, 20-50 parts of radix aconiti, 20-40 parts of radix aconiti kusnezoffii, 20-40 parts of rhizoma chuanxiong, 40-60 parts of raw loquat, 40-60 parts of caulis spatholobi, 10-20 parts of fructus lycii, 40-60 parts of semen cuscutae and 40-60 parts of radix achyranthis bidentatae. The scorpio has theeffects of relieving spasm by calming endogenous wind, activating meridians to stop pain and counteracting toxin and removing stasis; the prescription is mainly suitable for treating various kidney deficiency, nephritis, kidney stones, kidney cysts and nephrotic syndromes, and the early, middle and late stages of uremia, and has good curative effect on gynecological diseases and various malignanttumors; and ointment is prepared from pure natural traditional Chinese medicinal materials, no western medicine components are added in the preparation process, toxic and side effects are avoided, itching of individual patients after sticking is a normal reaction, and can be cured after scrubbing by ginger, and the ointment can be used continuously.

The invention relates to a water formula for treating gout diseases. The total amount of soluble solids is 200-800 mg / L, the calcium content is 60-120 mg / L, the magnesium content is 10-40 mg / L, the bicarbonate radical content is 150-450 mg / L, and the water formula also contains vanadium, lithium, sodium, potassium, strontium and selenium. The pH (Potential of Hydrogen) value is 7.6 to 8.2; the content of metasilicic acid is 50 mg / L; the hardness is 150 to 400 mg / L; the temperature is 36-48 DEG C; the traditional Chinese medicine composition has the advantages that gout can be effectively treated, and the uric acid index, the skin color, the urine, the physical strength, the spirit and the like of gout patients are comprehensively improved. The traditional Chinese medicine is safe to use and treat, free of toxic and side effects, free of treatment risks, convenient to treat, short in period and low in cost, and has good popularization prospects and commercial value.

The invention discloses a pill for preventing, curing and nursing kidney stone, which belongs to the field of traditional Chinese medicine. The pill comprises the following raw materials of effective components in parts by weight: 80-110 parts of radix rehmanniae, 70-90 parts of red flowers, 65-85 parts of longhairy antenoron herb, 50-70 parts of semen plantaginis, 45-60 parts of radix paeoniae alba, 40-55 parts of rhizoma alismatis, 35-50 parts of herba patriniae, 30-48 parts of spora lygodii, 28-45 parts of doorweed, 25-40 parts of fringed pink, 22-36 parts of endothelium corneum gigeriae galli, 18-30 parts of yam rhizome, 15-25 parts of silkworm excrement, 12-22 parts of akebia stem, 8-18 parts of tulips and 4-10 parts of cowherb seed. The pill disclosed by the invention is excellent in formula and proper in preparation, aims at multiple factors of increasing kidney burden, discriminates the pathogenesis of moist heat, yin deficiency, kidney deficiency and the like, selects a traditional Chinese medicinal material formula for clearing heat, eliminating dampness and nourishing yin, has the effects of invigorating kidney, alleviating water retention, treating stranguria and dispelling stones, is clinically verified to have good absorption effect and obvious curative effect and is suitable for being popularized and applied to clinically prevent and cure the kidney stone.

The present invention relates to: a novel method for preparing a heterocyclic derivative compound of chemical formula I below; a novel intermediate compound used in the preparation method; a composition for treatment or prevention of hyperuricacidemia, gout, nephritis, chronic renal insufficiency, nephrolith, uremia, urolithiasis, or a uric acid-related disease, the composition containing the compound of chemical formula I at a dose of more than 2 mg and equal to or less than 10 mg and being orally administered once a day; and a hydrochloride 1.5 hydrate of the novel compound of chemical formula I.

The present invention provides S-methyl-L-ergothioneine for use in diagnosis and / or prognosis. The invention also provides a method for the diagnosis and / or prognosis of a renal disease comprising the step of determining the amount of S-methyl-L-ergothioneine in an isolated test sample of a subject, and methods for deciding or recommending whether to initiate a therapeutic intervention or for determining the efficacy of a therapeutic intervention. It is also herein provided ergothioneine for use in the treatment and / or prevention of a renal lithiasis or an aminoaciduria, and ergothioneine for use in combination therapy.

The invention belongs to the technical field of medicine research and development, and particularly relates to a traditional Chinese medicine preparation for treating renal calculi. The traditional Chinese medicine preparation for treating renal calculi is prepared from the following raw materials in parts by weight: 15-35 parts of corn silk, 10-20 parts of talcum, 5-12 parts of fiveleaf akebia, 10-20 parts of deer's horn deglued, 6-12 parts of Diaphragma juglandis, 10-30 parts of fringed pink, 8-12 parts of cardamon, 9-16 parts of almond, 9-12 parts of Mangnolia officinalis, 18-35 parts of nduoh nyaatv buerng, 10-15 parts of delavay greenleaf elaeagnus leaf, 10-19 parts of pomegranate root, 6-10 parts of stem and leaf of Assam Crotalaria, 10-15 parts of lophatherum gracile and 9-13 parts of Tetrapanax papyriferus. The traditional Chinese medicine preparation for treating renal calculi has the advantages of small toxic and side effects, obvious curative effects and low recurrence rate after healing, and can treat both the symptoms and root causes. The preparation method of the traditional Chinese medicine preparation for treating renal calculi is simple, is low in cost and easy to operate, and can be easily popularized and applied.

The present invention relates to the use of theobromine or derivatives thereof as inhibitors of uric acid crystals in order to prevent uric acid crystal formation in urine and thus prevent nephrolithiasis or in particular uric acid nephrolithiasis.

The invention relates to the field of medicines, in particularly to a traditional Chinese medicine composition for treating kidney calculi. The traditional Chinese medicine composition comprises, by weight, 40-60 parts of incarvillea arguta and 20-28 parts of radix clematidis. The traditional Chinese medicine composition has the advantages that immune functions and the disease resistance of human bodies can be enhanced by the traditional Chinese medicine composition which is a medicine, and excellent effects of treating the calculi can be realized by the traditional Chinese medicine composition.

Provided herein are inhibitors of SLC26A3, which is an anion (CV, HCO3, oxalate) exchanger expressed in intestinal epithelial cells. SLC26A3 inhibitors have potential utility for treatment of constipation including chronic idiopathic constipation (CIC), opioid-induced constipation (OIC), constipation-predominant irritable bowel syndrome (IBS-C), cystic fibrosis-associated constipation, meconium ileus, distal intestinal obstruction syndrome, calcium oxalate kidney stone disease, enteric hyperoxaluria and primary hyperoxalurias.