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221 results about "Map Location" patented technology

Methods and compositions for the manipulation and characterization of individual nucleic acid molecules

A method for observing and determining the size of individual molecules and for determining the weight distribution of a sample containing molecules of varying size, which involves placing a deformable or nondeformable molecule in a medium, subjecting the molecule to an external force, thereby causing conformational and / or positional changes, and then measuring these changes. Preferred ways to measure conformational and positional changes include: (1) determining the rate at which a deformable molecule returns to a relaxed state after termination of the external force, (2) determining the rate at which a molecule becomes oriented in a new direction when the direction of the perturbing force is changed, (3) determining the rate at which a molecule rotates, (4) measuring the length of a molecule, particularly when it is at least partially stretched, or (5) measuring at least one diameter of a spherical or ellipsoidal molecule. Measurements of relaxation, reorientation, and rotation rates, as well as length and diameter can be made using a light microscope connected to an image processor. Molecule relaxation, reorientation and rotation also can be determined using a microscope combined with a spectroscopic device. The invention is particularly useful for measuring polymer molecules, such as nucleic acids, and can be used to determine the size and map location of restriction digests. Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and unfolding the molecules after they have been placed in a matrix.
Owner:WISCONSIN ALUMNI RES FOUND

Image processing and analysis of individual nucleic acid molecules

A method for observing and determining the size of individual molecules and for determining the weight distribution of a sample containing molecules of varying size, which involves placing a deformable or nondeformable molecule in a medium, subjecting the molecule to an external force, thereby causing conformational and/or positional changes, and then measuring these changes. Preferred ways to measure conformational and positional changes include: (1) determining the rate at which a deformable molecule returns to a relaxed state after termination of the external force, (2) determining the rate at which a molecule becomes oriented in a new direction when the direction of the perturbing force is changed, (3) determining the rate at which a molecule rotates, (4) measuring the length of a molecule, particularly when it is at least partially stretched, or (5) measuring at least one diameter of a spherical or ellipsoidal molecule. Measurements of relaxation, reorientation, and rotation rates, as well as length and diameter can be made using a light microscope connected to an image processor. Molecule relaxation, reorientation and rotation also can be determined using a microscope combined with a spectroscopic device. The invention is particularly useful for measuring polymer molecules, such as nucleic acids, and can be used to determine the size and map location of restriction digests. Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and unfolding the molecules after they have been placed in a matrix.
Owner:WISCONSIN ALUMNI RES FOUND

Image processing and analysis of individual nucleic acid molecules

A method for observing and determining the size of individual molecules and for determining the weight distribution of a sample containing molecules of varying size, which involves placing a deformable or nondeformable molecule in a medium, subjecting the molecule to an external force, thereby causing conformational and / or positional changes, and then measuring these changes. Preferred ways to measure conformational and positional changes include: (1) determining the rate at which a deformable molecule returns to a relaxed state after termination of the external force, (2) determining the rate at which a molecule becomes oriented in a new direction when the direction of the perturbing force is changed, (3) determining the rate at which a molecule rotates, (4) measuring the length of a molecule, particularly when it is at least partially stretched, or (5) measuring at least one diameter of a spherical or ellipsoidal molecule. Measurements of relaxation, reorientation, and rotation rates, as well as length and diameter can be made using a light microscope connected to an image processor. Molecule relaxation, reorientation and rotation also can be determined using a microscope combined with a spectroscopic device. The invention is particularly useful for measuring polymer molecules, such as nucleic acids, and can be used to determine the size and map location of restriction digests. Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and unfolding the molecules after they have been placed in a matrix.
Owner:WISCONSIN ALUMNI RES FOUND

Image processing and analysis of individual nucleic acid molecules

A method for observing and determining the size of individual molecules and for determining the weight distribution of a sample containing molecules of varying size, which involves placing a deformable or nondeformable molecule in a medium, subjecting the molecule to an external force, thereby causing conformational and / or positional changes, and then measuring these changes. Preferred ways to measure conformational and positional changes include: (1) determining the rate at which a deformable molecule returns to a relaxed state after termination of the external force, (2) determining the rate at which a molecule becomes oriented in a new direction when the direction of the perturbing force is changed, (3) determining the rate at which a molecule rotates, (4) measuring the length of a molecule, particularly when it is at least partially stretched, or (5) measuring at least one diameter of a spherical or ellipsoidal molecule. Measurements of relaxation, reorientation, and rotation rates, as well as length and diameter can be made using a light microscope connected to an image processor. Molecule relaxation, reorientation and rotation also can be determined using a microscope combined with a spectroscopic device. The invention is particularly useful for measuring polymer molecules, such as nucleic acids, and can be used to determine the size and map location of restriction digests. Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and unfolding the molecules after they have been placed in a matrix.
Owner:WISCONSIN ALUMNI RES FOUND

Methods and apparatus for providing map locations in user applications using URL strings

In one illustrative example, a method for use in mapping a location in a computer device includes the steps of receiving an electronic file or message which includes a hypertext link mapping indicator associated with a uniform resource locator (URL) string having a server address and latitude and longitude coordinates; receiving, through a user interface of the computer device, an end user selection of the hypertext link mapping indicator in the electronic file or message; and in response to the end user selection of the hypertext link mapping indicator: if a predetermined type of mapping application is provided in the computer device, invoking a mapping function of the mapping application to produce a map of a location corresponding to the latitude and longitude coordinates for visual display in a display of the computer device (e.g. based on received maplet data); and if the predetermined type of mapping application type is not provided in the computer device, requesting and receiving map data from a map coordinating server identified by the server address of the URL string to produce a map of the location for visual display in the display (e.g. based on a bitmap image). Advantageously, processing of the received hypertext link mapping indicator is handled differently depending on the type of device or whether a predetermined mapping application is installed in the device, so that optimal mapping functionality is provided for different device environments.
Owner:MALIKIE INNOVATIONS LTD

System and method for surgical instrument disablement via image-guided position feedback

A system for selectively disabling a surgical instrument operating in a surgical site of a region of interest of a living subject. In one embodiment, the system includes means for noninvasively placing a number of fiducial markers in an anatomic space of the region of interest of the living subject, means for pre-operatively measuring a location of each fiducial marker in the anatomic space, an imaging acquisition device for pre-operatively acquiring an image volume from the region of interest of the living subject, a probe for intra-operatively monitoring a location of the surgical instrument in the anatomic space, and a controller configured to perform the steps of identifying a centroid of each fiducial marker in the image volume, registering the identified centroid of each fiducial marker in the image volume to the measured location of the corresponding fiducial marker in the anatomic space to determine a registration transformation, mapping the monitored location of the surgical instrument in the anatomic space onto a corresponding location in the image volume by an inverse of the registration transformation, and generating a signal to disable the surgical instrument when the mapped location of the surgical instrument is substantially close to a boundary of the surgical site of the region of interest in the image volume.
Owner:VANDERBILT UNIV

Image processing and analysis of individual nucleic acid molecules

A method for observing and determining the size of individual molecules and for determining the weight distribution of a sample containing molecules of varying size, which involves placing a deformable or nondeformable molecule in a medium, subjecting the molecule to an external force, thereby causing conformational and/or positional changes, and then measuring these changes. Preferred ways to measure conformational and positional changes include: (1) determining the rate at which a deformable molecule returns to a relaxed state after termination of the external force, (2) determining the rate at which a molecule becomes oriented in a new direction when the direction of the perturbing force is changed, (3) determining the rate at which a molecule rotates, (4) measuring the length of a molecule, particularly when it is at least partially stretched, or (5) measuring at least one diameter of a spherical or ellipsoidal molecule. Measurements of relaxation, reorientation, and rotation rates, as well as length and diameter can be made using a light microscope connected to an image processor. Molecule relaxation, reorientation and rotation also can be determined using a microscope combined with a spectroscopic device. The invention is particularly useful for measuring polymer molecules, such as nucleic acids, and can be used to determine the size and map location of restriction digests. Breakage of large polymer molecules mounted on a microscope slide is prevented by condensing the molecules before mounting and unfolding the molecules after they have been placed in a matrix.
Owner:WISCONSIN ALUMNI RES FOUND

System and method for surgical instrument disablement via image-guided position feedback

A system for selectively disabling a surgical instrument operating in a surgical site of a region of interest of a living subject. In one embodiment, the system includes means for noninvasively placing a number of fiducial markers in an anatomic space of the region of interest of the living subject, means for pre-operatively measuring a location of each fiducial marker in the anatomic space, an imaging acquisition device for pre-operatively acquiring an image volume from the region of interest of the living subject, a probe for intra-operatively monitoring a location of the surgical instrument in the anatomic space, and a controller configured to perform the steps of identifying a centroid of each fiducial marker in the image volume, registering the identified centroid of each fiducial marker in the image volume to the measured location of the corresponding fiducial marker in the anatomic space to determine a registration transformation, mapping the monitored location of the surgical instrument in the anatomic space onto a corresponding location in the image volume by an inverse of the registration transformation, and generating a signal to disable the surgical instrument when the mapped location of the surgical instrument is substantially close to a boundary of the surgical site of the region of interest in the image volume.
Owner:VANDERBILT UNIV

Network server emergency information accessing method

InactiveUS8116723B2Emergency connection handlingDevices with sensorAutomated crash notificationNetwork service
A Means and Methods for providing a PSAP with means for tracking the real time location of a wireless telephone that connects to an Internet server upon detection of predefined events or reception of a command from a person to do so and transmits location information and event data to said server for viewing by authorized users. The server also displays a telephone number for a PSAP having jurisdiction over the location of the wireless telephone. Said PSAP telephone numbers being stored in a server data base and providing a means whereby a person logged-onto the server can call this PSAP telephone number, explain the reason for the call, provide the call taker with log-on information allowing access to the server and the data transmitted from the wireless telephone so that he can access mapped location information showing the location of the wireless telephone and then take appropriate action. Methods for delivering vehicle Automatic Crash Notifications to a PSAP, for establishing VoIP communications with crash victims and for providing crash data and video information to emergency responders showing the injury level of crash victims is disclosed as well as a video security system with multiparty command dialed PSAP notification voice calls and audio, video and location data transmission to the server. Satellite security telephones, offender monitoring devices, child safety telephones and medical alert notification embodiments of the invention are also disclosed.
Owner:KALTSUKIS CALVIN L

Methods and apparatus for providing map locations in user applications using URL strings

In one illustrative example, a method for use in mapping a location in a computer device includes the steps of receiving an electronic file or message which includes a hypertext link mapping indicator associated with a uniform resource locator (URL) string having a server address and latitude and longitude coordinates; receiving, through a user interface of the computer device, an end user selection of the hypertext link mapping indicator in the electronic file or message; and in response to the end user selection of the hypertext link mapping indicator: if a predetermined type of mapping application is provided in the computer device, invoking a mapping function of the mapping application to produce a map of a location corresponding to the latitude and longitude coordinates for visual display in a display of the computer device (e.g. based on received maplet data); and if the predetermined type of mapping application type is not provided in the computer device, requesting and receiving map data from a map coordinating server identified by the server address of the URL string to produce a map of the location for visual display in the display (e.g. based on a bitmap image). Advantageously, processing of the received hypertext link mapping indicator is handled differently depending on the type of device or whether a predetermined mapping application is installed in the device, so that optimal mapping functionality is provided for different device environments.
Owner:MALIKIE INNOVATIONS LTD
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