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An information processing system has an electronic device and a controller for control of a functionality of the device. An abstract representation of the functionality is provided to the controller. The abstract representation exposes a modality of controlling the functionality. The controller enables controlling the functionality through interaction with the abstract representation. The modality controls associating the control of the functionality with a modally compatible controlling capability of the controller. The modality exposed can be, for example, "Boolean", "float", "integer array".

Systems and methods for the aggregation, analysis, and display of data for used vehicles are disclosed. Historical transaction data for used vehicles may be obtained and processed to determine pricing data, where this determined pricing data may be associated with a particular configuration of a vehicle. The user can then be presented with an interface pertinent to the vehicle configuration utilizing the aggregated data set or the associated determined data where the user can make a variety of determinations. This interface may, for example, be configured to present the historical transaction data visually, with the pricing data such as a trade-in price, a list price, an expected sale price or range of sale prices, market low sale price, market average sale price, market high sale price, etc. presented relative to the historical transaction data.

The object of the present invention is to provide an image-analysis apparatus that is capable of correlating and understanding organ function and tubular structure. The image-analysis apparatus performs image analysis based on image data, and comprises: a function-map-creation device which creates a function map based on function data that shows the functions of an organ; and an overlay device which correlates and overlays tubular-structure data for the tubular structure of the organ onto the function map.

A concept-based back translation system includes a target language semantic parser module, a source language semantic parser module, a bi-directional machine translation module, a relevancy judging module, and a back translation display module.

A restraint system for use in a passenger seating area of a motor vehicle includes a seat belt assembly disposed adjacent the passenger seating area which is adjustable between a stowed position and at least one deployed position. The seat belt assembly including a webbing positionable across the body of an occupant and an inflatable section disposed within the webbing adjustable between a deflated condition and an inflated condition by a source of gas pressure. An anchor is disposed opposite the seat belt assembly adjacent the seating area and includes a receiving element adapted to engage and secure the belt assembly. A controller monitors vehicle conditions and is operative to inflate the inflatable section such that the belt assembly is placed in a deployed position for securement around an occupant in a vehicle.

Method and processing system for measuring the intelligibility of a degraded output signal (Y(t)) from an audio transmission system (10) in response to a reference input signal (X(t)). A measurement device (11) is arranged for outputting a measure (I) for the speech intelligibility of the output signal (Y(t)). The measurement device (11) executes processing of the input signal (X(t)) and output signal (Y(t)) to obtain a disturbance density function (D(f)_n). The disturbance density function (D(f)_n) is corrected by multiplying it with a correction function for each frame derived from a correlation calculation of the compensated pitch power densities (PPX′(f)_n) associated with the input signal (X(t)) of a present frame (n) and an independent previous frame (n−2). The corrected disturbance density function (D′(f)_n) is aggregated over frequency and time to obtain a measure (I) for the speech intelligibility of the output signal (Y(t)).

The multi-screen casting system for a flipped teaching classroom contains, with the classroom, at least a receiving screen having a video/audio receiving interface connected to a multimedia streaming device, a set of at least two inter-casting devices, and a wireless broad band base station providing dual-band (2.4 GHz and 5.0 GHz) WiFi LAN communications. The multimedia streaming device contains firmware for locating and processing video/audio transmission within the WiFi LAN, and presenting received video/audio or data on the connected receiving screen. Each inter-casting device is one of a notebook computer, a smart phone, and a tablet computer. The inter-casting devices conduct, in a time-sharing manner, peer-to-peer communications among themselves and many-to-one communications to the multimedia steaming device of the receiving screen.

Disclosed are editing methods that are added to speech-based searching to allow users to better understand textual queries submitted to a search engine and to easily edit their speech queries. According to some embodiments, the user begins to speak. The user's speech is translated into a textual query and submitted to a search engine. The results of the search are presented to the user. As the user continues to speak, the user's speech query is refined based on the user's further speech. The refined speech query is converted to a textual query which is again submitted to the search engine. The refined results are presented to the user. This process continues as long as the user continues to refine the query. Some embodiments present the textual query to the user and allow the user to use both speech-based and non-speech-based tools to edit the textual query.

The present invention is a system and method for optimizing electrical circuits by means of derivative-free optimization. Tunable parameters such as component values, transistor sizes or model parameters are automatically adjusted to obtain an optimal circuit. Any method of measuring the performance of the circuit, including computer simulation, can be incorporated into the optimization technique, with no derivative requirements. An arbitrary continuous optimization problem can be posed, including an objective function, equality and inequality constraints, and simple bounds on the tunable parameters. The optimization technique is efficient and guarantees that it will find a locally optimal solution from any starting point. Further, the procedure includes a method of automatically recovering from electrical failure to enable automatic and productive circuit optimization. A set of measurement widgets is provided to automatically introduce the checking required to recover from electrical failure. The automated circuit optimization leads to higher quality circuits, increases designer productivity, results in a better understanding of the tradeoffs inherent in the circuit and lifts the thinking of the circuit designer to a higher level.

Techniques for storing omics data that indicates long sequences of elements associated with a particular biological molecule include receiving digital omics data comprising over two kilobytes. The digital omics data is split into multiple partitions. The maximum partition size is much less than then a number of elements in a typical instance of the particular biological molecule. Each partition is encrypted. Each encrypted partition is inserted into a corresponding data packet that includes an owner field that uniquely indicates an owner of the omics data. Each data packet is uploaded into a non-centralized, peer-to-peer distributed storage network. Thus, genome data is encrypted and stored in a distributed, scalable, fully decentralized, fast, and highly secure network. The network further provides for decentralized computing, trustless validation of the genomes by way of oracles and trustless genome analysis by third party providers through smart contracts.

Disclosed are antimicrobial peptides with useful or superior properties such as antimicrobial activity, desirable levels of hemolysis, and advantageous therapeutic index against various microorganisms, especially Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus. Also provided are methods of to control microbial growth and pharmaceutical compositions to treat or prevent microbial infections. Certain peptides are disclosed utilizing a structure-based rational modification of antimicrobial peptide D1, with single D-/L-amino acid substitutions or charged residue substitutions in or near the center of the peptide on the nonpolar or polar face, or peptides with one or more amino acids in the D configuration, and peptides with all amino acids in the D configuration. Modified peptide analogs herein can demonstrate one or more properties such as improved antimicrobial activity, specificity, and resistance to degradation. Compositions disclosed herein are useful as antibiotics, including as broad spectrum antibiotics.

Devices, systems, and methods for neuromodulation are provided. For example, a neuromodulation system is disclosed that comprises an implantable neuromodulation module having a photodiode configured to generate electrical current in response to receiving light from an optical fiber; an optical transceiver; and at least one electrode configured to provide electrical stimulation to a nerve utilizing the electrical current generated by the photodiode. As another example, a method of neuromodulation is disclosed that comprises receiving light at a photodiode of a neuromodulation module and generating electrical current in response to receiving the light; and providing, via at least one electrode of the module positioned within the patient, electrical stimulation to a nerve of the patient utilizing the electrical current generated by the photodiode.

Any issues associated with manufacture of a part are identified and highlighted on a part model. A software method and system then uses motion of the part model for communicating the manufacturability issues to the customer. The motion can include a repositioning of a part rendering to a preferred orientation position, a fly-around so the customer can appreciate the next zoom location, and then a zooming in on the issue desired to be shown. Alternatively or in conjunction with the zooming and fly-around motion, the orientation of the part rendering showing the manufacturability issues can be three-dimensionally manipulated such as with a click-drag-drop command of the customer's computer mouse. By adding a moveable aspect to the communication, customers can much better understand which changes are recommended or required of the part.

An integrated electronic medical records and health care management system includes a managing application for receiving and storing member data associated with at least one member of a health plan. A risk assessment application coupled to the managing application generates a level of care for the member based upon the member data. A member safety knowledge database stores medication interaction data, and a clinical protocols knowledge database stores treatment data relating to the treatment of a plurality of health-related conditions. The managing application generates a plan of care for the member based upon the member data and member's level of care, the medication interaction data, and the treatment data. The managing application also monitors implementation of the member's plan of care and updates the plan of care based upon the implementation of the member's plan of care. The managing application may further generate coverage data indicating whether costs associated with a health-related service selected for the member are covered by the member's health insurance policy. The system may also include remote access server for enabling communication between the managing application and one or more remote terminals to enable automatic updating of data stored in the managing application and data collected and stored by the remote terminals.

Association of Type II diabetes and a locus on chromosome 5q35 is disclosed. In particular, the gene SLIT-3 with this locus is shown by linkage analysis to be a susceptibility gene for Type II diabetes. Pathway targeting for drug delivery and diagnosis applications in identifying those have Type II diabetes or at risk of developing Type II diabetes, in particular those that are non-obese are described.

The present invention provides methods for the synthesis and/or discovery of inorganic compounds, including organometallic compounds. Also provided are functional nucleic acids for synthesis of inorganic compounds and methods of identifying the same. As another aspect, the invention provides compounds made according to the inventive methods, including palladium plates and cobalt-iron oxides spheres, cubes, fibers and nanotubes.

Provided is a method for conceptualizing protein interaction networks. The method conceptualizes and simplifies complicated and enormous protein interaction networks wherein the method comprises the steps of (a) conceptualizing protein nodes that form the protein interaction network as gene ontology concepts to reconfigure the network; (b) integrating nodes including the same concepts in the reconfigured network into one node to generate the network by means of exact match; and (c) integrating several nodes having similar concepts in the generated network into one node to reconfigure the generated network by means of approximate match.