Multielement nutrition compound and preparing method thereof

Abstract

The invention discloses a multielement nutrition compound comprising the following components in percentage by weight: 70-90% of calcium phosphate, 0-0.3% of silicon, 0-0.5% of strontium, 0-0.5% of zinc, 0.5-2.0% of magnesium, 0.5-10% of vitamin, 0.5-10% of amino acid and 1.0-10% of carbohydrate, wherein at least two substances of silicon, strontium and zinc are not zero at the same time. The invention has the preparing method that fruits, nuts, vegetable juice and inorganic salt containing strontium, zinc and silicon are added into simulated physiological solution, the mixed liquor is aged at the temperature of 35-120 DEG C to separate out granules, and the obtained product is filtered, washed and dried to obtain the multielement nutrition compound. The invention has simple preparing technology and does not relate to high-temperature heat treatment, and granule size, total calcium containing ratio, trace element doping ratio and organic nutrient substance molecule doping ratio are easy to control; the release rate of active substance is easy to regulate and control. The multielement nutrition compound of the invention not only can supplement calcium and phosphorus but also can supplement trace elements and various organic nutrient substances. The multielement nutrition compound can be used for the additive of health food or beverage, performs the efficacies of regulating bodymetabolism, increasing bone strength and preventing various nutrient deficiency diseases from happening.

Description

technical field [0001] The invention relates to a calcium phosphate compound which contains various trace elements and organic nutrients and has the functions of regulating human body metabolism and preventing various nutritional deficiency diseases and a preparation method thereof, which belongs to the field of human nutrition and health food. Background technique [0002] Various metabolic diseases are caused by imbalance or long-term lack of calcium, phosphorus, trace elements, amino acids, vitamins, sugar and other nutrients in the human body, such as short stature, muscle contraction, and weight loss caused by bone development retardation from infants to young adults. Being underweight, weak and prone to diseases, etc.; another example is osteoporosis, high blood pressure, diabetes, etc. caused by the decline in metabolic capacity of middle-aged and elderly people. It is one of the most common diseases in the world, and osteoporosis causes bone Complications of osteopor...

AI Technical Summary

Problems solved by technology

[0005] In the prior art, Chinese patent CN1436539A discloses an iron-zinc-calcium blood-supplementing calcium-supplementing drink in terms of trace element synergistic calcium supplementation drinks, but the drinks developed from ferrous fumarate, fully soluble pearl powder, zinc sulfate, etc. The controllability of the dissolution rate is poor, the dissolution rate of pearl powder calcium carbonate is too slow, and the fast-dissolving iron and zinc are not easily absorbed by the digestive system, so the absorption rate is low

Chinese patent CN1140023A discloses a selenium-enriched tea rich in trace elements such as selenium, zinc, germanium, copper, manganese and a teabag made of Chinese herbal medicines such as Gynostemma pentaphyllum, in order to invigorate the kidney and spleen, nourish qi and blood, nourish yin and help yang The purpose of promoting body fluid and nourishing the stomach, etc., but the effect on improving bone metabolism, increasing bone strength and reducing osteoporosis is not clear

Other traditional Chinese medicine drinks that improve the function of the spleen and stomach also have problems such as unclear effects on improving bone strength

It is particularly worth noting that a large number of health drinks developed with soluble trace element inorganic salts as raw materials in the prior art, such as sodium selenite, zinc sulfate, zinc sulfate, ferrous sulfate, copper sulfate, etc., although they can It quickly reaches a very high concentration level, but due to the poor control of release, it has disadvantages such as a large loss ratio of active substances, low absorption rate, and obvious peak and valley concentrations, and a high dose of a certain trace element in a short period of time causes metabolic disorders of other active ions, which has serious negative effects. risks of

[0006] There is no doubt about the specific biological efficacy of various trace elements in balancing and regulating the metabolism of human tissues, but relevant research results have also confirmed that a single trace element such as silicon, magnesium, strontium or zinc has a role in the regulation of osteoblast activity and bone tissue metabolism. Significant dose-dependent relationship, release of excessively high doses of silicon, magnesium, strontium or zinc can cause cytotoxicity or cause other ion metabolism disorders (Dahl S.G., Bone 2001, 28, 446; GoughJ.E., Biomaterials 2004, 25, 2039; Ito A., Mater.Sci.Eng.C 2002, 22, 21; Saravanapavan P., Key Eng.Mater.2004, 254-256, 785); On the contrary, long-term lack of these trace elements in bone tissue will cause tissue distortion or even serious illness

In the prior art, there are also researchers trying to introduce silicon, magnesium, strontium or zinc into crystalline tricalcium phosphate or hydroxyapatite by doping and other ways to introduce a single biologically active substance, but crystalline tricalcium phosphate or hydroxyapatite Stone has high stability, and its dissolution rate is extremely slow, so it is difficult for compound doped trace elements to reach the dose level required to improve bone metabolism

Chinese patent CN1212126C discloses a mechanically mixed calcium supplement of nano-hydroxyapatite and trace elements. The compound form and introduction method of trace elements are not clear, so the release rate cannot be effectively guaranteed.

However, so far, in the research on calcium phosphate mineral nutritional drinks and food, there have been no reports on the synergistic compounding of multiple trace elements and organic nutrients to achieve a more effective improvement in the absorption of calcium-containing mineral drinks and food and bone metabolism.

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