The invention discloses a low-power consumption and high integration main board with a plurality of expansion interfaces. The low-power consumption and high integration main board with the plurality of expansion interfaces comprises a main board of a printed circuit, a central process unit (CPU) and a South Bridge chip, wherein the CPU and the South Bridge chip are integrated on the main board. A UNI-peripheral component interface express (PCIE) expansion interface, a high-definition multimedia interface (HDMI) / digital video interactive (DVI) / data processing (DP) control module, a PCIE control module, a hard disk control module, a universal serial bus (USB) control module, a recommend standard (RS) 232 / 422 / 485 control module, a voice frequency control module, a control signal module and a line print terminal (LPT) parallel interface control module are arranged on the main board. Pins are arranged in the UNI-PCIE expansion interface, wherein the pins correspond to the above-mentioned control modules. The pins are respectively connected with the above-mentioned modules through drive circuits. Compared with the prior art, the low-power consumption and high integration main board with the plurality of expansion interfaces achieves the unification of a plurality of external interfaces through the UNI-PCIE expansion interface, so that the structure of the main board becomes simple and attractive and manufacturing cost and energy consumption of the main board are reduced.