An osteotomy guide (2,102,302) is provided for cutting a bone, such as the medial distal tibia (50), for example, to facilitate an ankle replacement. The osteotomy guide (2,102,302) includes a positioning device (4,104,304) having a number of fixation points (6,8; 106, 108), a first guide member (10, 110) structured to align with a first portion (52) of the bone (50), in order to perform a first procedure on the first portion (52), and a second guide member (12,112,312) structured to align with a second portion (54) of the bone (50), in order to perform a second procedure on the second portion (54). The fixation points (6,8;106,108) engage the bone (50) and maintain alignment of the first guide member (10,110) with respect to the first portion (52) of the bone (50) during the first procedure, and maintain alignment of the second guide member (12,112,312) with respect to the second portion (54) of the bone (50) during the second procedure, in order that the first procedure and the second procedure are substantially reproducible.