The invention discloses a multifunctional local burn dressing change isolating device. The multifunctional local burn dressing change isolating device comprises a base, a stepping motor, a rotating shaft, a gear, a rack plate, a chute, a trigger plate, a first travel switch, a second travel switch, an electric push rod, a placement box, a first pocket groove, a discharge pipe, a cover box, a second pocket groove, a temperature controller, a temperature sensor, a protecting shield, a semiconductor refrigerator, a connecting tube and an adjusting valve. Firstly, a burnt limb of a patient can be supported, isolated and protected, and dressing change of the patient is facilitated; secondly, by a temperature control mechanism, constant-temperature protection on the burnt limb of the patient can be implemented, and wound inflammation caused by high environment temperature is avoided; and finally, the oxygen content of the region of the burnt limb of the patient is increased by simple operation, namely, by increasing of the oxygen content, recovery of the burn wound of the limb of the patient is promoted. Therefore, while the postoperative rehabilitation effect of the patient is greatly improved, clinic operation of medical staff is facilitated, and popularization and application of the medical industry are facilitated.