53 results about "Fibromyalgia syndrome" patented technology

A method for treatment or prophylaxis of a disease state or other physiological condition, e.g., autism, delayed development, acid reflux disease, vaginal yeast infections, impaired hearing, chronic ear infections, seasonal allergies, Fibromyalgia syndrome, Crohn's disease, colitis, irritable bowel syndrome, interstitial cystitis, acne, sinusitis, rheumatoid arthritis, chronic fatigue syndrome, asthma, attention deficit disorder, attention deficit/hyperactivity disorder, rosacea, multiple sclerosis, hyperglycemia, or Ménière's disease, by administration of an anti-fungal composition that includes at least one of the bacilli (1) Bacillus subtilis, (2) Lactobacillus sporogenes, and (3) Streptococcus faecalis.

The present invention relates to a method of treating disorders including cognition impairment, generalized anxiety disorder, acute stress disorder, social phobia, simple phobias, pre-menstrual dysphoric disorder, social anxiety disorder, major depressive disorder, eating disorders, obesity, anorexia nervosa, bulimia nervosa, binge eating disorder, substance abuse disorders, chemical dependencies, nicotine addiction, cocaine addiction, alcohol addiction, amphetamine addiction, Lesch-Nyhan syndrome, neurodegenerative diseases, late luteal phase syndrome, narcolepsy, psychiatric symptoms anger, rejection sensitivity, movement disorders, extrapyramidal syndrome, Tic disorder, restless leg syndrome, tardive dyskinesia, sleep related eating disorder, night eating syndrome, stress urinary incontinence, migraine, neuropathic pain, diabetic neuropathy, fibromyalgia syndrome, chronic fatigue syndrome, sexual dysfunction, premature ejaculation, and male impotence. This method involves administering to a patient in need of such treatment a therapeutically effective amount of a disclosed compound. Such compounds are 4-phenyl substituted tetrahydroisoquinolines having the Formula IA, IB, IIA, IIB, IIIA or IIIC as set forth herein.

The invention is directed to a method of treating fibromyalgia syndrome in a subject, comprising administering a therapeutically effective amount of a carbamoyl compound, or pharmaceutically acceptable salt thereof.

The present invention relates to a pharmaceutical composition for treating, for example, a disorder or condition selected from the group consisting of hypertension, depression, generalized anxiety disorder, phobias, posttraumatic stress disorder, avoidant personality disorder, sexual dysfunction, eating disorders, obesity, chemical dependencies, cluster headache, migraine, pain, Alzheimer's disease, obsessive-compulsive disorder, panic disorder, memory disorders, Parkinson's diseases, endocrine disorders, cerebellar ataxia, gastrointestinal tract disorders, negative symptoms of schizophrenia, premenstrual syndrome, Fibromyalgia Syndrome, stress incontinence, Tourette syndrome, trichotillomania, kleptomania, male impotence, cancer, chronic paroxysmal hemicrania and headache in a mammal, preferably a human, comprising (i) an atypical antipsychotic or a pharmaceutically acceptable salt thereof,

• • (ii) a 5-HT_1B receptor antagonist or a pharmaceutically acceptable salt thereof, wherein the 5-HT_1B receptor antagonist is selected from the group consisting of (A) a compound of the formula I as described in the specification and (B) a compound of the formula II as described in the specification, and optionally (iii) a pharmaceutically acceptable carrier.

Highly selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agorophobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de la Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, visceral pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.

The present invention relates to methods and compositions comprising ribose and maleate for the treatment of fibromyalgia syndrome. The methods and compositions of the invention are especially useful for oral administration and are useful for alleviating the symptoms of pain, fatigue, and irritable bowel syndrome in fibromyalgia syndrome.

Methods for treating fatigue associated with fibromyalgia by administering high-dose milnacipran to a patient suffering from such fatigue are provided. Also provided are methods for the long-term treatment of fatigue associated with FMS by administering milnacipran to a patient suffering from such fatigue.

Compositions and methods for alleviating the symptoms associated with chronic fatigue syndrome and fibromyalgia syndrome are provided. The compositions are based on use of a transdermal gel formulation delivery system for androgens, either alone or in combination with other hormones.

The present invention provides a method of treating fibromyalgia syndrome (FMS), chronic fatigue syndrome (CFS), and pain in an animal subject comprising administering a therapeutically effective amount of a dual serotonin norepinephrine reuptake inhibitor compound or a pharmaceutically acceptable salt thereof, wherein said dual serotonin norepinephrine reuptake inhibitor compound is characterized by a non-tricyclic structure and a greater inhibition of norepinephrine reuptake than serotonin reuptake, and wherein said compound is not administered adjunctively with phenylalanine or tyrosine. In particular, the use of milnacipran to treat FMS, CFS, and pain is disclosed.

Selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agoraphobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de la Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.

Provided are a sustained-release composition including pregabalin and a pharmaceutically acceptable salt thereof using a gastroretentive drug delivery system (GRDDS), an oral sustained-release formulation using the composition, and a preparation method thereof. In a sustained-release composition according to the present invention and a formulation including the same, a coating compartment including a sugar or a derivative thereof and a plasticizer is introduced onto the outer surface of pregabalin having a less stable structure to ensure stability and to improve compatibility with excipients at the same time, and also to effectively control the release rate. As a result, dosing convenience is improved to provide a gastroretentive drug delivery system having enhanced patient compliance. Therefore, the present invention may exhibit improved therapeutic or prophylactic effects on various neurological diseases, such as neuropathic pain, epilepsy, fibromyalgia syndrome, etc., which have not been easily accomplished due to the characteristics of pregabalin.

The present invention provides a method for treating certain rheumatic conditions such as fibromyalgia syndrome, chronic fatigue syndrome, myofascial pain syndrome, and Gulf War syndrome, among others, by administration of trimetazadine, along with related compositions and kits.

The invention discloses an orally-taken traditional Chinese medicine composition for treating fibromyalgia syndrome. The traditional Chinese medicine composition is prepared from the following material medicines: herba epimedii, rhizoma curculiginis, prepared rehmannia root, eclipta, obscured homalomena rhizome, pyrola, radix curcuma, rhizoma drynariae, corydalis amabilis, rhizoma smilacis glabrae, liquidambar formosana hance and long-noded pit viper. Compared with the common antidepressant, muscle relaxant, anticonvulsive drugs, and the like, the orally-taken traditional Chinese medicine composition for treating fibromyalgia syndrome has the advantages of positive curative effect, small side effect, high compliance of a patient and the like.

The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of autonomic and other neurological disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of neurogenic orthostatic hypotension (NOH), as well as NOH associated with multiple system atrophy (MSA), familial amyloid polyneuropathy (FAP), pure autonomic failure (PAF), and Parkinson's disease (PD), intradialytic hypotension (IDH) or hemodialysis-induced hypotension, hypotension associated with fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS).

The invention discloses a tradtional Chinese medicine composition for treating female fibromyalgia syndromes. The tradtional Chinese medicine composition is prepared from the following raw materials: fructus broussonetiae, mulberry, tortoise shell, dogwood, cortex cinnamomi, fructus citri, flos rosae rugosae, tribulus terrestris, valerian, nacre mother of pearl, platycodon grandiflorum, fevervine, rhizoma gastrodiae, herba aristolochiae and tamarix chinensis. The tradtional Chinese medicine composition for treating female fibromyalgia syndromes correspond with the female physiological characteristics; compared with the frequently-used antidepressant, muscle relaxant and anticonvulsant, the pharmaceutical composition has the advantages of being definite in curative effect, small in side effect and high in patient compliance; and therefore, the tradtional Chinese medicine composition is a dedicated drug for treating female fibromyalgia syndromes.

The purpose of the present invention is to provide a compound that exerts a strong analgesic action against on pain, in particular, against neuropathic pain and/or fibromyalgia syndrome. The present invention provides a cyclic amine derivative represented by chemical formula (AA), a prodrug thereof or a pharmaceutically acceptable salt thereof.

The present invention provides for the use of a heterocyclic amine-type compound to prepare a medicament for the treatment of symptoms of fibromyalgia syndrome, or chronic fatigue syndrome.

The invention discloses a traditional Chinese medicine preparation for treating fibromyalgia syndrome and a preparation method, belonging to the field of traditional Chinese medicines. The active ingredients of the traditional Chinese medicine preparation consist of the following raw materials: ramulus mori, herba euonymi, abutilon, laciniate blumea herb, rabdosia amethystoides, radix rubiae, buchtorm libanotis root, japanese saussurea herb, lily, juncus roemerianus, poria with hostwood, bitter bamboo leaf, polygonum bistorta, pinellia cordata, ambergris and rhizoma typhonii. The medicinal materials of the traditional Chinese medicine preparation disclosed by the invention are proper in compatibility and conform to the theories of the traditional Chinese medicine and the modern medicine; the traditional Chinese medicine preparation has the functions of clearing heart and tranquilizing mind, relieving pain and diminishing swelling, dispelling wind and removing dampness and clearing heat and removing toxicity and is convenient to use and realizes a good absorption effect without adverse or toxic and side effects; and according to clinical verification, the traditional Chinese medicine preparation has perfect effects of relieving and treating fibromyalgia syndrome and is suitable for popularization and application to the clinical treatment and nursing of fibromyalgia syndrome.