1006 results about "Findings methods" patented technology

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like.

The invention discloses a mine finding method based on a cube forecasting model with three-dimensional modeling, characterised in that having following steps: (1) collecting data; (2) establishing a database; (3) establishing a three-dimensional mine model; (4) establishing a cube forecasting model; (5) validating a forecasting result. The invention can find a mine in a large scale study region where a twodimensional mine finding method can't realized by using the method of three-dimensional modeling during a mine finding process, the obtained forecasting result can reflect an actual situation more factually. With the cube forecasting model with three-dimensional modeling, various three-dimensional space data can be used to establish a three-dimensional geological model, a three-dimensional mine model and a three-dimensional mine finding model of the study region, the forecasting result is qualified in position, quantity and probability. Accordingly, the ''cube forecasting model'' mine finding method realizes a development from the two-dimensional mine finding to the three-dimensional mine finding, has important theory value and application value.

A method for target device discovery on a network is disclosed. The method includes multicasting a signal from a master initiator over the network. A unicast is received from a new target recently connected to the network where the new target is passive when no multicast signal from the master initiator is received. Then the new target is added to a list of targets connected to the network. The method concludes by sending out a next multicast to other initiators where the next multicast includes information regarding the adding of the new target to the network.

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like.

The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, mitochondrial F₁F₀ ATP hydrolase associated disorders, and the like.

A core configuration discovery method and corresponding microprocessor are provided that does not rely on off-core logic or queries by system BIOS. Reset microcode is provided in the microprocessor's cores. Upon reset, the microcode queries and/or receives from other cores configuration-revealing information and collects the configuration-revealing information to determine a composite core configuration for the microprocessor. The composite core configuration may reveal the number of enabled cores, identify the enabled cores, reveal a hierarchical coordination system of the multi-core processor, such as a nodal map of the cores for certain inter-core communication processes or restricted activities, identify various domains and domain masters within such a system, and/or identify resources, such as voltage sources, clock sources, and caches, shared by various domains of the microprocessor. The composite core configuration may be used for power state management, reconfiguration, and other purposes.

The invention discloses a financial network unusual transaction community finding method based on information entropy. The method includes the specific steps of firstly, analyzing the process and the mode of an unusual transaction, and extracting features of block transactions and suspicious transactions; secondly, storing transaction amounts and traction frequency information of accounts through an adjacent matrix so as to quantize the features; thirdly, defining the information entropy of nodes; fourthly, conducting community division and finding on the financial network nodes according to the financial network unusual transaction community finding method based on the information entropy; fifthly, evaluating the community finding result. Firstly, accuracy of unusual transaction account identification and unusual transaction communication division which are achieved according to the method is calculated, and then the structure of the unusual transaction community is evaluated through the community evaluation index modularity Q. The community finding method based on the information entropy is applied to the anti-money laundering field for the first time, the money laundering accounts can be identified and tracked by finding the unusual transaction community, and unusual transactions can be prevented by analyzing the relations and the transaction laws between money laundering accounts.

The invention discloses a network hot event detection method based on text classification and clustering analysis. The method solves the problem that the efficiency and accuracy rate of the existing network hot event detection method based on clustering analysis need to be improved. The method comprises the steps that feature words are respectively selected for various classes of files through feature extraction and feature selection by utilizing a training corpus; each training text and test text are represented as vectors in all of the feature spaces by utilizing a vector space model method, and the weight of each dimension of the vectors is determined by utilizing a TF-IDF (term frequency-inverse document frequency) method, and then each test text is classified; the classified test texts in different classes are respectively subjected to clustering analysis, so the hot cluster of each class is obtained, the feature word representing the hot event is obtained through further analysis, and then the word property and other aspects of each feature word are analyzed; the description of each hot event is generated by utilizing relevant language knowledge and necessary linguistic organization. With the network hot event detection method based on text classification and clustering analysis, the detection efficiency and accuracy rate of hot events can be effectively improved.

This invention relates to the methods for the identification and isolation of cancer stem cells from cultured cancer cell lines. Cell line-derived cancer stem cells isolated using the present methods may be useful, for example, in assays to screen compounds for anti-cancer stem cell activity and in target discovery methods for identifying novel expressed genes and druggable targets. The invention also relates to the screening of compounds for activity against cell line-derived cancer stem cells.

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like.

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like.

Disclosed are a terminal registration method, a terminal discovery method, a terminal and a service device in the present application. The service device includes: a registration module (22) for receiving the registration of the terminal, assigning a Proximity-based Services identifier (ProSe ID) to the terminal, and associating application information of the terminal with the ProSe ID, wherein, the application information includes information for identifying applications; a discovery module (24) for instructing a base station to allocate discovery resources to the terminal, and transmitting a discovery result, wherein, the discovery resources are used for discovery between two terminals. By setting a ProSe service module, the present application can provide the support for ProSe services in the aspect of network architecture.

The invention discloses a vehicle positioning method and a vehicle finding method in a parking lot. The vehicle positioning method comprises the following steps: acquiring the position of the entrance of the parking lot through a GPS of a mobile terminal before a vehicle enters the parking lot; after the vehicle enters the parking lot, acquiring the traveling track of the vehicle through an inertia measurement device of the mobile terminal; when detecting the advancing state changes from a travelling stage to a walking stage, by using the inertia measurement device of the mobile terminal after the vehicle is parked,, at the moment, calculating the parking position according to the position of the entrance of the parking lot and the traveling track through the mobile terminal, and recording the parking position. The vehicle finding method in the parking lot comprises the vehicle positioning method as well as the following steps: when a user finds the vehicle, acquiring the present position of the user through the GPS and/or manual input through the mobile terminal; generating a vehicle finding route from the present position of the user to the parking position through the mobile terminal, and guiding the user to find the parking position according to the vehicle finding route. The vehicle positioning method and the vehicle finding method in the parking lot are low in cost, high in practicability, high in feasibility and easy to popularize.

The embodiment of the invention discloses a finding method and a finding device for group fraud. The method comprises the steps of performing community division on network relation data in a network database at regular intervals to acquire at least one first community; computing feature index information of the first community according to feature information of each node in the at least one first community; and predicting a group fraud risk of the first community according to the feature index information. In the prior art, when in anti-fraud, anti-fraud is performed by mainly performing all-round evaluation on individuals, and the method for effectively monitoring and investigating the group fraud risk is lacked. According to the finding method for group fraud provided by the embodiment of the invention, after the community division is performed on the network relation data, the group fraud risk of the divided community is predicted according to the feature index information, monitoring on the group fraud is achieved, and security of financial Internet can be improved.

An information processing apparatus is used in a network including an information apparatus compatible with the universal-plug-and-play (UPnP) discovery and control method and an information apparatus compatible with the Web based discovery and control method and includes a browser support unit for converting the Web based discovery and control method to the UPnP discovery and control method and a server support unit for converting the UPnP discovery and control method to the Web based discovery and control method. The information apparatus compatible with the UPnP discovery and control method and the information apparatus compatible with the Web based discovery and control method can acquire device information from each other and control the device by each other.

A method of epitope discovery comprising the step of selecting an epitope from a population of peptide fragments of an antigen associated with a target cell, wherein the fragments have a known or predicted affinity for a major histocompatibility complex class I receptor peptide binding cleft, wherein the epitope selected corresponds to a proteasome cleavage product of the target cell.

The present invention concerns methods and reagents useful in target discovery. Specifically, the invention relates to small nucleic acid molecules capable of mediating RNA interference (RNAi), such as short interfering nucleic acid (siNA) short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods of target discovery using siRNA.