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4 results about "Immunological tests" patented technology

Method for detecting a test substance, and labeling buffer and kit therefor

A detection method for detecting a substance to be detected in an immunological test sample, the detection method comprising a labeling step in which a complex of the substance to be detected and a labeling body is formed in the presence of at least one selected from imidazole and derivatives thereof, a pH buffer, and a polyvalent metal ion, the labeling body comprising a first probe molecule capable of binding to the substance to be detected and a label.
Owner:FUJIREBIO CO LTD

O-type foot-and-mouth disease virus polyepitope virus-like particle nanogen and preparation method and application thereof

ActiveCN120209160BHepatitis B virus core AntigenAntigen epitope
The application discloses an O-type foot-and-mouth disease virus multi-epitope virus-like particle nano-antigen and a preparation method and application thereof. The nano-antigen is obtained by sequentially connecting antigen epitopes of three topological representative strains O / Tibet / CHA / 99, O / Mya98 / BY / 2010, OZK / 93, O / XJPS / CHA / 2017 and O / HKN / 2007 of the O-type foot-and-mouth disease virus in sequence, introducing a T cell epitope of a 3A gene of the foot-and-mouth disease virus at a C terminal, and finally inserting a woodchuck hepatitis B virus core antigen, and an amino acid sequence of the nano-antigen is shown as SEQ ID NO. 6. Immunological test results show that the nano-antigen has good antigenicity, a vaccine prepared from the nano-antigen can not only induce high-level protective antibodies, but also protect immunized animals against virus attack. In addition, the nano-antigen has immunoprotective effects on the O-type foot-and-mouth diseases of pigs, cattle and sheep. The application provides an effective technical means for preventing and controlling and purifying the foot-and-mouth disease.
Owner:LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES(LANZHOU BRANCH CENTER OF CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER)

A rheumatism immunity detection report generation method, system, device, medium and product

PendingCN122337456ADiseaseRheumatism
This application relates to the field of data processing technology, and in particular to a method, system, device, medium, and product for generating rheumatoid and immunological test reports. The method includes receiving a VCF file from NGS sequencing, a report output directory, and a report output template to generate an order number; naming the VCF file, patient information file, quality control parameter file, and filter parameter file according to a naming convention including the order number, and saving them to the report output directory; extracting patient information, quality control parameters, filter thresholds, and a list of target rheumatoid and immunological diseases, and combining the paths of relevant files to generate, verify, and save a configuration file containing the order number to the report output directory; starting a Docker container to analyze the VCF file, and automatically filling the analysis results, patient information, and quality control parameters into the report output template, generating and saving a rheumatoid and immunological test report containing the order number to the report output directory, thus achieving fully automated generation and analysis from data input to result output.
Owner:AFFILIATED HOSPITAL OF INNER MONGOLIA MEDICAL UNIV (INNER MONGOLIA AUTONOMOUS REGION CARDIOVASCULAR INST)

A Mycoplasma pneumoniae antibody detection kit based on immunoturbidimetry

PendingCN122307101AAntigenBlood markers
This invention discloses a Mycoplasma pneumoniae antibody detection kit based on immunoturbidimetry, belonging to the field of clinical immunology testing. It includes solutions R1 and R2. Solution R1 is a dispersion of double-coupled latex microspheres coated with natural Mycoplasma pneumoniae antigens, and solution R2 is a sample diluent containing an enhancer. The test samples can be serum, plasma, or whole blood samples, and it is applicable to biochemical analyzers, protein analyzers, or combined blood cell and immunoturbidimetric analyzers. The kit prepared by this invention can be used on various instruments, has a wide range of detection targets, and can be coupled with other instruments to detect various clinically valuable blood indicators, further shortening the testing time. It solves the problems of poor accuracy, low efficiency, and limited application scenarios caused by the subjective interpretation of results, long processing time, and limited applicability of blood samples in existing technologies. It can effectively simplify the testing process and improve diagnostic efficiency.
Owner:CHONGQING ZHONGMEI ZHONGYI BIOENGINEERING CO LTD