25results about "Oxygenators" patented technology

A blood pump-oxygenator system (250A, 250B, 250C) for increasing perfusion and oxygen levels in the body of a patient (P), comprising: a blood inlet (80) and a blood outlet (90) connected to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of the blood of the patient; a first blood pump (11) and a first oxygenator (20), wherein the first blood pump (11) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the first oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The system further comprises a second blood pump (13) and a second oxygenator (21), wherein the second blood pump (13) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the second oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The circuit comprises a first branch (101) and a second branch (102) arranged in parallel with each other, the first branch (101) accommodating the first blood pump (11) and the first oxygenator (20), and the second branch (102) accommodating the second blood pump (13) and the second oxygenator (21). The system further comprises a pump control unit (290) wherein the first and second blood pumps (11, 13) are configured to be controlled by the pump control unit (290) to increase or decrease the blood flow through the corresponding oxygenator (20, 21) by changing the proportion of the blood flow through the first and second oxygenator (20, 21).

The present invention relates to a method by which intravenous fluids, blood or artificial blood containing high levels of mechanically infused dissolved oxygen can be used to maintain appropriate oxygen levels in venous blood to provide short term oxygenation support to a compromised patient or trauma patient. In one aspect, a system and method for oxygenating a biological fluid for a compromised subject or trauma subject in need of oxygenation support to maintain the subject at an appropriate oxygen level is provided, the method comprising: supplying oxygen from an oxygen source; and dissolving an amount of the supplied oxygen into the biological fluid to obtain an oxygen enriched biological fluid.

The invention relates to a device for the controlled in vivo absorption of CO2, comprising a catheter which has a gas-permeable membrane and a CO2-absorbing carrier medium. The invention additionally relates to a set comprising said device and to the device or set for use in the prophylaxis or treatment of diseases of the respiratory system or for use in the induction of hypercapnia in a patient.

A foam management system (1000), apparatus (300), and method are disclosed for a foamed blood product , the apparatus comprising an antifoaming device (400) for receiving a pressurized foam (60) from a pressurized foamed blood product, said antifoaming device allowing a gas (68) to be separated from said foam (60), wherein said antifoaming device converts said pressurized foam (60) into said blood product, allowing the blood product to be recovered from said foam (60), substantially without the foam.

An advanced system and methods for treatment of cancer and other diseases including complications from late-stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish a continuous extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. An innovative concept inherent in the instant invention is the incorporation of an ECMO machine to provide oxygenation. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed.

This invention relates to a process through which intravenous fluids, blood, or artificial blood containing high-levels of mechanically-injected dissolved oxygen can be used to maintain appropriate oxygen levels in the venous blood and thereby provide short-term oxygenation support for compromised or trauma patients. In one aspect, there is provided a system and process for oxygenating a biological fluid for use in a compromised or a trauma subject in need of oxygenation support to maintain appropriate oxygen levels in the subject, the process comprising: supplying oxygen gas from an oxygen source; and dissolving an amount of the supplied oxygen into a biological fluid to obtain an oxygen enriched biological fluid.

The present disclosure provides systems and methods for controlling gas-enrichment, e.g., oxygen-enrichment, therapy. One or more sensors and / or one or more imaging systems may be used to measure or determine one or more physiological parameters of a patient. Feedback regarding the one or more physiological parameters or microvascular resistance may be provided to titrate or control the gas-enrichment therapy.

A method for onsite hemorrhage control in trauma patients using a portable rapid autotransfusion device can involve recovering a first portion of patient blood from an extravascular space into a fluid reservoir of the device. A negative internal pressure can be applied to the blood. The blood can be conditioned, such as by oxygenating and removing carbon dioxide. The conditioned blood can be returned to the patient intravenously at a rate that matches the rate of blood recovery, ensuring that the net volume of returned blood is maintained substantially equal to the net volume of removed blood.

To provide a catheter that can be reduced in diameter, can reduce a load on the heart, and can effectively deliver oxygenated blood to important organs.SOLUTION: A catheter includes: a tubular main body that can be inserted into a blood vessel of a patient; and a first opening that is formed at a position spaced by a predetermined distance from a distal end portion of the main body, is formed so as to be inclined from a distal end side toward a proximal end side of the main body, and is configured to send oxygen-added blood flowing inside the main body into the blood vessel of the patient.SELECTED DRAWING: Figure 4

The present disclosure relates to intracorporeal gas exchange systems and methods in conditions associated with hypoxia and hypercarbia. The present disclosure envisages an intracorporeal oxygenation system comprising a blood oxygenator having a blood compartment and a gas compartment. The blood and gas compartments are separated by a gas permeable barrier so as to allow exchange of carbon dioxide in blood in the blood compartment with oxygen in the gas compartment. The system comprises a catheter device for insertion in a blood vessel of human comprising an interior portion and an exterior portion wherein the interior portion (100a) comprises an annular housing, a plurality of capillary conduit, a pumping device, an air sensing device, a blood sensor and a collar. The present disclosure also relates to a method of oxygenating a deoxygenated blood in a human and also to a method for treating a human suffering from hypoxia or hypercarbia.

A system for priming a fluid system includes a fluid connector configured to interface with a fluid source and a fluid reservoir including a first connector configured to couple with an inflow line of the fluid system, a second connector configured to couple with an outflow line of the fluid system, and a gas release valve. A system for priming a fluid system includes first and second fluid connectors configured to interface with a fluid source, a first connector configured to couple with an inflow line of the fluid system, a second connector configured to couple with an outflow line of the fluid system, and a gas release valve. A method of priming the fluid system includes coupling the first connector with the inflow line, coupling the second connector with the outflow line, coupling the first fluid connector with the fluid source, and elevating the fluid source.

A foam management system (1000), apparatus (300), and method are disclosed for a foamed blood product, the apparatus comprising an antifoaming device (400) for receiving a pressurized foam (60) from a pressurized foamed blood product, said antifoaming device allowing a gas (68) to be separated from said foam (60), wherein said antifoaming device converts said pressurized foam (60) into said blood product, allowing the blood product to be recovered from said foam (60), substantially without the foam.

A perfusion system for treatment of a patient experiencing at least one medical condition includes a reservoir configured to receive perfusate, a cannula configured to fluidly couple the reservoir to an arterial blood vessel of a mammal through a single entry point, a fluid line fluidly coupling the reservoir to the cannula, a pressure sensor configured to measure pressure along the fluid line, a flow sensor configured to measure a flow rate along the fluid line; and a pulse generation system. The pulse generation system includes a pulse generator configured to generate pulsatile flow of perfusate from the reservoir to the cannula along the fluid line based on one or more signals generated by at least one of the pressure sensor or the flow sensor. The perfusion system is configured to perfuse an entire circulatory system of the mammal to treat a patient experiencing at least one medical condition.

The blood pump-oxygenator system (1; ,...; 10) comprises at least one blood pump (11), at least one oxygenator (20, 21), a blood inlet (80) and a blood outlet (90) connected together to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of patient blood, wherein the first blood pump (11) is configured to deliver blood through the circuit from the patient (P) to the blood inflow port (80), through the oxygenator (20, 21) and out of the blood outflow port (90) back into the patient (P). The system (1; ,...; the device (10) further comprises a recirculation loop (100) arranged between the blood inlet (80) and the blood outlet (90), where the recirculation loop (100) houses a first blood pump (11) and an oxygenator (20, 21), where the first blood pump (11) is configured to circulate at least a portion of the blood in the loop through the recirculation loop (100) such that the blood passes through the oxygenator (20, 21) multiple times, and where the first blood pump (11) is configured to circulate at least a portion of the blood in the loop through the recirculation loop (100). Blood is repeatedly subjected to an exchange of O2 and CO2 in oxygenators (20, 21). At least one first valve (31) is provided between the recirculation loop (100) and the blood flow outlet (90) and is configured to control an amount of blood flowing through the recirculation loop (100).

A perfusion system for treatment of a patient experiencing at least one medical condition includes a reservoir configured to receive perfusate, a cannula configured to fluidly couple the reservoir to an arterial blood vessel of a mammal through a single entry point, a fluid line fluidly coupling the reservoir to the cannula, a pressure sensor configured to measure pressure along the fluid line, a flow sensor configured to measure a flow rate along the fluid line; and a pulse generation system. The pulse generation system includes a pulse generator configured to generate pulsatile flow of perfusate from the reservoir to the cannula along the fluid line based on one or more signals generated by at least one of the pressure sensor or the flow sensor. The perfusion system is configured to perfuse an entire circulatory system of the mammal to treat a patient experiencing at least one medical condition.

An improved method and device for improved catheters and / or related technologies. The device generally comprises an improved medical technology. The provided device substantially improves upon catheter-related medical device technology.

The present disclosure provides systems and methods for controlling gas-enrichment, e.g., oxygen-enrichment, therapy. One or more sensors and / or one or more imaging systems may be used to measure or determine one or more physiological parameters of the patient. Feedback regarding one or more physiological parameters or microvascular resistance may be provided for titrating or controlling the gas-enrichment therapy.

According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to draw blood from a patient into a fluid flow path at a rate, for example, of 5-7 liters per minute. The system may include one or more heat exchangers coupled to the fluid flow path and configured to heat the blood, for example, to a temperature above 42 degrees Celsius and below 43.2 degrees Celsius.

An improved method and device for improved catheters and / or related technologies. The device generally comprises an improved medical technology. The provided device substantially improves upon catheter-related medical device technology.

The present disclosure relates to an intracellular device for delivering therapeutics. The device may be an in vivo electroporation device which may include at least one electrode needle adapted to produce an electric field and a plurality of infusion ports on at least one axially extending line along the length of the needle configured to deliver a therapeutic substance. The device may include a retractable insulating sheath configured to limit a treatment field of the device, and a penetration limiting means configured to limit the depth of insertion of the electrode needle. The device may include an injection needle configured to deliver a therapeutic substance and at least two electrode needles adapted to produce an electric field, which may cause poration of the target tissue's cells for uptake of the therapeutic substance.

A neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the tubular body includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, an outer jacket surrounding the helical coil, and an opening at the distal end. Adjacent windings of the helical coil are spaced progressively further apart in the distal direction. The opening at the distal end of the tubular body is enlargeable from a first inside diameter for transluminal navigation to a second, larger inside diameter to facilitate aspiration of thrombus into the lumen.

To provide improved methods and apparatus for improved catheters and / or related technologies. [Solution] An alternating flow catheter 20 is shown, comprising an outer catheter 30, an inner catheter 40, a catheter cap 50, and one or more balloons 60. The outer catheter 30 further has one or more distal axial holes 32, one or more proximal holes 34, a fixed area 36, ​​and a check valve 38. The inner catheter 40 further has one or more distal axial holes, one or more proximal holes 44, and an alternating flow control mechanism.

To easily and rapidly remove gases through a semipermeable membrane in a bilateral aqueous environment. A method for influencing the concentration of gases such as oxygen and / or carbon dioxide in a substance mixture or solution of a biological or complex chemical liquid is described. The substance mixture or solution is conducted along an asymmetric semipermeable membrane on one side, while on the other side of the same membrane, an oxygenated dialysate is conducted in a closed circuit including an oxygenator. The substance mixture or solution to be influenced contains a particulate gas carrier, and the dialysate contains a gas carrier for at least one of the gases to be influenced in the closed circuit, so that the gas to be influenced is transported as close as possible to the substance mixture or solution. For regeneration, the dialysate is regenerated by introducing fresh oxygen and / or removing carbon dioxide.

Methods and systems for bidirectional priming of a blood circuit while a catheter is connected to the circuit that delivers gas-enriched blood to a patient. The system primes the circuit while the catheter is connected to the circuit by controlling a first flow control mechanism to close to prevent blood flow through the draw line to a catheter and causes a pump to circulate blood in a first direction through a mixing chamber and / or through a bubble trap that removes air bubbles from the circuit. The system controls a second flow control mechanism to close to prevent blood flow in a return line to the catheter while causing the first flow control mechanism to open after the second flow control mechanism is closed and while causing the pump to circulate the blood in a second, opposite direction through the mixing chamber that removes air bubbles from the circuit.

A medical gas delivery system and a ventilator system are provided. The medical gas delivery system includes an electrolytic gas generation device, a delivery device, and a control unit. The electrolytic gas generation device is used to generate a first gas and a second gas. The delivery device is in fluid communication with the electrolytic gas generation device, and is used to transport a medical gas. The medical gas includes at least one of the first gas and the second gas. The control unit is electrically connected with the electrolytic gas generation device and the delivery device, so as to control a component ratio of the medical gas.