The invention discloses an artificial intelligence control unit fixing device, and relates to the technical field of intelligent control unit fixing devices, the artificial intelligence control unit fixing device comprises a fixing base, a heat dissipation mechanism and a clamping and locking mechanism, a fixing bottom plate is arranged at one end of the outer wall of the fixing base close to the bottom end, and a wire groove is formed in one end of the top end of the fixing bottom plate away from the fixing base. By arranging a connecting box, a heat dissipation bin, an air inlet hole, an exhaust hole, an S-shaped water pipe, a first filter screen, an exhaust fan, a second filter screen, a heat dissipation hole, a water inlet connector and a water outlet connector, rapid heat dissipation of the control unit can be achieved, and heat absorption and cooling can be conducted on the control unit in the control unit box through cooling liquid in the S-shaped water pipe; the air flow can be formed in the heat dissipation bin through the exhaust fan to accelerate cooling of the control unit and the S-shaped water pipe, in addition, the water inlet connector and the water outlet connector can be connected with external cooling liquid to achieve circular flowing of the cooling liquid, and the operation stability of the control unit can be effectively improved through mutual cooperation of the multiple parts.