The invention discloses a mobile network service adaptation method, a device, a base station and a mobile communication system, and relates to the technical field of mobile communication. The method comprises the steps of a base station receiving an RRC message from a terminal, wherein the RRC message comprises one or more pieces of NAS PDU information; the base station determining the slice typeaccording to the format type of the NAS PDU information, and determining a core network entity based on the mapping relation between the pre-configured service slice and the core network entity; the base station generating a service establishment request message or an uplink data indication message, and sending the messages to a core network entity corresponding to the slice type, so that the corenetwork entity allocates resources for acceptable services. According to the method, device, terminal, base station and system, the base station determines a core network entity for bearing the services through the NAS PU in a service establishment request message, and directly sends the service establishment request message to the core network entity carrying the services. The service establishment time delay is reduced, the core network signaling is reduced, and the service establishment efficiency is improved.