The invention discloses a quick cleaning device for floor-to-ceiling windows of a building, which comprises a support seat, a water storage tank is connected to the middle part of the upper end of the support seat, a water diversion chamber is arranged at the right end inside the water storage tank, a water diversion pump is arranged inside the water diversion chamber, and the upper end of the support seat is connected to the right side. There is a support frame, the bottom of the front support frame is provided with a drive motor, the front end of the drive motor is connected to a reducer, the reducer is connected to a driving pulley, the upper end of the drive pulley is connected to a driven belt through a belt, and the middle part of the driven belt is connected to a rotating belt. Rod, the middle part of both ends of the rotating rod is connected with a rotating gear, the upper end of the rotating gear is meshed with a driving gear, the middle part of the upper end of the driving gear is connected with a driving screw, the middle part of the driving screw is connected with a slider, the sliders are connected with a lifting plate, and the right end of the lifting plate is connected There is a cleaning rod, and the right end of the cleaning rod is connected with a cleaning device. The present invention realizes the up and down movement of the cleaning device, increases the cleaning efficiency of the floor-to-ceiling windows of buildings, and makes it unnecessary to spray water additionally when cleaning the floor-to-ceiling windows.