58 results about "Quinone methide" patented technology

An olefinically unsaturated monomer is stabilized by a retarder-containing composition which comprises a solvent and a quinone methide as a retarder.

Quinone methide derivatives such as 4-benzylidene-2,6-di-tert-butyl-cyclohexa-2,5 dienone are used to inhibit styrene monomer polymerization in the dehydrogenator portion of a styrene monomer production system. The inhibitor contacts the dehydrogenation effluent and does not partition in substantial amounts to the aqueous phase that is separated in the phase separator.

Disclosed are compositions and synthesis methods that pertain to biocompatible polymeric capsules capable of undergoing backbone degradation and cargo release upon exposure to biologically relevant concentrations of hydrogen peroxide (50-100 μM of H₂O₂). In the invention, bio-responsive polyester bearing boronic ester triggers groups that degrade upon exposure to low concentrations of H₂O₂. The degradation is induced by transformation of a boronic ester to a phenol, which undergoes a quinone methide rearrangement to break down the polyester backbone.

The present invention relates to additive composition for control and inhibition of polymerization of styrene, wherein the composition comprises amine and quinone methide, and wherein the amine is polymerization non-inhibitor amine. In one embodiment, the present invention relates to method of preparation and use of additive composition to control and inhibit polymerization of styrene, wherein the composition comprises amine and quinone methide, and wherein the amine is polymerization non-inhibitor amine. In another embodiment, the present invention relates to additive composition for control and inhibition of polymerization of styrene, wherein the composition comprises oxide treated derivative of amine and quinone methide, and wherein the amine is polymerization non-inhibitor amine, and to the method of preparation and use thereof.

The invention provides a method for synthesizing 7-Acetyleno quinone methide compounds that is safe and inexpensive. The method avoids the need for extremely cold reaction temperatures and unlike the prior art does not require any highly explosive materials. The method comprises the steps of

• • a) performing a condensation reaction between 3,5-di-tert-butyl-4-hydroxybenzaldehyde and a secondary amine thereby forming a secondary amine quinone methide intermediate;
  • b) removing water from the secondary amine quinone methide intermediate by azeotropic distillation;
  • c) adding the dehydrated secondary amine quinone methide intermediate to an organic medium containing a metal acetylide to form a Mannich base intermediate; and
  • d) adding a release agent to the Mannich base intermediate to yield a 7-Acetyleno quinone methide.

The invention discloses water-soluble triterpenephenol compounds having antitumor activity represented by formula (I), wherein the substituents R₁˜R₄ and M are defined as in the description. The invention also discloses a method for preparing the compounds of formula (I) used quinone methide triterpene compounds as starting materials. The water-soluble triterpenephenol compounds disclosed in the invention can be made into various dosage forms including injection, tablet, capsule, granule and liniment, particularly suitable for making into injection.

Polymeric substrates, for example polyolefins such as polypropylene, can be made flame retardant by the incorporation therein of a synergistic mixture of (i.) at least one compound selected from the group consisting of nitroxyl stabilizers, hydroxylamine stabilizers, nitrone stabilizers, substituted hydroxylamine stabilizers, amine oxide stabilizers, benzofuranone stabilizers, phosphite and phosphonite stabilizers, quinone methide stabilizers and monoacrylate esters of 2,2′-alkylidenebisphenol stabilizers and (ii.) at least one compound selected from the group consisting of brominated flame retardants, phosphorus containing flame retardants and inorganic flame retardants such as ammonium polyphosphate or decabromodiphenyl oxide; wherein the amount of organic or inorganic flame retardant of component (ii.) required to achieve an acceptable level of flame retardancy is significantly reduced compared to that needed when component (i.) is not present.

A process for inhibiting the polymerization of cyclopentadiene compounds (B) by contacting the cyclopentadiene compound with a quinone methide compound (A) of structure (I),

Compositions (AB) comprising (A) and (B) are also provided.

Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties.

The present invention provides a method for inhibiting unwanted polymerization of reactive monomers within a liquid. The method comprises the combined usage of a quinone methide with a quinone diimide to the liquid monomer. This combination has an unexpected synergistic effect. Thus, in some ratios, the combination results in practically 100% inhibition.

The invention provides an oxa-Michael addition reaction method to generate o-quinone methides by Sc(III) catalysis of alcohols. 2-(Hydroxy(phenyl)methyl)phenol compounds and alcohol compounds are catalyzed by Sc(III) to generate o-quinone methides in situ and cause oxa-Michael addition reaction; product yield reaches 88-98%. The method herein is simple to perform; the materials and reagents are simple; the reaction product yield is high; the defect that the traditional methods employ expensive catalysts and have strict conditions is avoided; the product is easy to separate and purify; the method herein is important to the methodological study on o-quinone methides and is important to total synthesis of natural products and discovery of drugs.