6 results about "Acetylide" patented technology

The application discloses a method for synthesizing organic acetylide ester through a palladium catalytic reaction and belongs to the field of organic synthesis. The organic acetylide ester is obtained through a cross-coupling reaction in the presence of a palladium catalyst, a phosphine ligand and an alkali, with terminal alkyne and di-tert-butyl dicarbonate as raw materials. The method has the advantages of high reaction yield, wide substrate range, good functional group compatibility, and the advantages of non-toxic and easy-to-obtain carbonyl source, simple operation steps and mild reaction conditions.

This invention discloses a visible light-induced method for synthesizing α,β-unsaturated acetylide amides, belonging to the field of organic synthesis. The invention constructs a visible light-responsive aromatization-driven carbamoyl radical precursor—a dihydroquinazolinone derivative precursor containing a carbamoyl segment. Under direct visible light irradiation, a single-electron process is triggered, leading to C-C bond cleavage and aromatization, thereby efficiently releasing a carbamoyl radical in situ. Subsequently, this radical undergoes selective acetylation transfer and coupling with an acetylation-based high-valent iodine reagent, achieving the rapid construction of the target α,β-unsaturated acetylide amide. This process can be completed via a one-pot pathway of "visible light direct-driven—radical generation—acetylation transfer / coupling," avoiding the introduction of additional photocatalysts, making the reaction system simpler, the cost more controllable, and the post-processing more convenient.

The application discloses a transition metal-free method for preparing o-iodophenyl acetylide, which uses o-dihalobenzene and terminal alkyne as raw materials, and reacts to obtain o-iodophenyl acetylide in the presence of alkali metal hydride; preferably, the reaction is carried out in a solvent. Specifically, the alkali metal hydride is added into the solvent, then the terminal alkyne compound is added, stirred for 5 min, and then the o-dihalobenzene is added, and the reaction is carried out at 0-60 DEG C to obtain the alkylation product o-iodophenyl acetylide. The method is simple in operation, mild in reaction condition, and can be easily scaled up, and does not need any metal additive or anhydrous condition.

The application discloses a copper acetylide hydrochlorination complex catalyst and a preparation method and application thereof, and is characterized in that the catalyst comprises 2,2'-dipyridyl-4,4'-diphosphoric acid. The ligand in the catalyst is a nitrogen-containing heterocyclic compound, so that the catalyst has good stability; the catalyst can inhibit the oxidation-reduction reaction of acetylene and divalent copper ions, and prolongs the service life; and the catalyst has the advantages of simple preparation process, high production efficiency, high atomic utilization rate, high catalyst dispersity and high catalytic conversion rate.

The invention relates to a preparation method of graphene, which mainly comprises the following steps: firstly, preparing a metal acetylide with the thickness of 0.2-1000 nanometers on a substrate, and covering a water film; by utilizing a photo-thermal reaction, the metal acetylide is initiated to be decomposed and graphene is formed; and finally, stripping the substrate from the graphene, and cleaning to obtain the graphene with a specific size. Compared with the like, the invention is more economical, efficient, stable and environment-friendly, and has obvious overall advantages.

The present invention provides (6Z,9Z)-6,9-dodecadien-1-yne of the following formula (1). Furthermore, the present invention provides a process for preparing (6Z,9Z)-6,9-dodecadien-1-yne (1) comprising reacting a (3Z,6Z)-10-halogeno-3,6-decadiene compound of the following general formula (2), wherein X represents a halogen atom, with a metal acetylide of the following general formula (3), wherein M represents Na, Li, K, Ag, Cu(I), MgZ, CaZ or Cu(II)Z, wherein Z represents a halogen atom or an ethynyl group, to form (6Z,9Z)-6,9-dodecadien-1-yne (1).