22results about How to "Avoid expensive" patented technology

The invention belongs to the technical field of protein structure prediction, and relates to a protein structure prediction method, system and device based on a light quantum computer, and the method comprises the steps: 1) obtaining a multi-sequence alignment MSA matrix of a target sequence based on the target sequence alignment of a to-be-predicted protein; 2) encoding the obtained multi-sequence alignment MSA matrix into a {0, 1} matrix; 3) converting the amino acid interaction of the protein into an undirected graph model of {0, 1} state nodes, and training by adopting a Boltzmann machine training mechanism and using a light quantum computer to obtain a weight coefficient of a connecting edge between the nodes in the undirected graph model; and 4) obtaining an interaction coefficient between different amino acids of the protein based on the weight coefficient. According to the method, the calculation efficiency and the solving result of protein structure prediction are improved, and the problems that complex scheduling problems are difficult to calculate and accurate solutions cannot be obtained in the prior art are solved.

The invention discloses a preparation method of fiazonetin, and belongs to the technical field of medicinal chemistry. According to the route, 2-halo-3-methylpyrazine which is low in price and easy to obtain is used as a raw material and sequentially reacts with hydrazine hydrate and orthoester, and then a hydrogenation reduction reaction is performed to generate a compound 4; carrying out chiral resolution or chiral separation on the compound 4 and carrying out condensation reaction on the compound 4 and p-fluorobenzoyl halide to obtain an intermediate compound 5 or 5'and a new intermediate compound 6; reacting the compound 6 with a halogenating reagent to obtain a compound 7; carrying out Suzuki coupling reaction on the compound 7 and a compound 8 to obtain a compound, namely, the compound of the formula A, namely, non-azonepan; according to the route, the raw materials are simple, easy to obtain and low in cost; the reaction is simple, the preparation efficiency is high, and the reaction yield of each step can be higher than 90%; no harsh reaction conditions exist, and operation is safe; post-treatment is simple and convenient, and environmental pollution is low. The method is suitable for large-scale production; a high-chiral product can be obtained, the chiral purity value of a final product is as high as 99.5%, and the method has relatively good market value and profound practical significance. # imgabs0 #

The invention provides a method for separating and repairing a heterogeneous positive electrode black powder material, which comprises the following steps of: performing carbonization heat treatment on the heterogeneous positive electrode black powder material to obtain a carbonized heterogeneous positive electrode black powder material; mixing the carbonized heterogeneous positive electrode black powder material with a density heavy liquid, and carrying out cyclone separation treatment to respectively obtain a heavy product and a light product; and mixing the heavy product with a lithium source, and carrying out lithiation calcination treatment to obtain the nickel cobalt lithium manganate positive electrode material. Carrying out oxidation sintering treatment on the light product to obtain a sintered material, mixing the sintered material with a carbon source and a lithium source, and carrying out thermal reduction treatment to obtain a lithium iron phosphate positive electrode material; the heterogeneous anode black powder material comprises a mixed material of ternary nickel cobalt lithium manganate anode material black powder and lithium iron phosphate anode material black powder. According to the separation and restoration method, no strong acid, strong base or waste liquid is generated, no heavy metal is lost, efficient recovery and utilization of key elements on the material level are achieved, and density heavy liquid and water for washing can be recycled.

The application provides a preparation method of a benzaldehyde aniline compound and relates to the technical field of organic synthesis. The preparation method provided by the application comprises the following steps: in a solvent, with an alkali as a promoter, under an atmosphere with an oxygen concentration of 20v100%, the temperature of a reaction system is controlled to be 50-70 DEG C, a diphenyl ketone compound I is reacted with an aniline compound II to generate a benzaldehyde aniline compound III, and the reaction product is subjected to column chromatography separation to obtain a pure benzaldehyde aniline compound III. The method has the beneficial effects that the reaction is simple, green and environment-friendly, the use of an expensive transition metal catalyst is avoided, the reaction condition is mild and controllable, and an environment-friendly byproduct is generated.

The invention relates to the field of synthesis of pyrazolone, and provides a method for synthesizing a pyrazolone structure by utilizing carbon dioxide aiming at the problem that an expensive transition metal catalyst and high-toxicity carbon monoxide are needed for synthesizing pyrazolone by utilizing carbonylation reaction, and the reaction formula is as follows: # imgabs0 # reaction conditions are as follows: in the presence of carbon dioxide, in an organic solvent and under the action of alkali, the reaction is carried out for 1-3 hours, so that the pyrazolone structure is synthesized by utilizing carbon dioxide. And reacting the compound II with carbon dioxide to obtain the pyrazolone structure. According to the method, the pyrazolone structure is synthesized in a green and efficient manner by utilizing carbon dioxide.

The invention relates to a spring force clamping connection for clamping a cable comprising an insulating sheath in an uninsulated manner, wherein at least one electrical conductor is arranged in the insulating sheath, wherein the spring force clamping connection has at least one busbar and a clamping spring, wherein the clamping spring has a clamping leg, which is configured for clamping the electrical conductor at a contact section of the busbar, and a bearing leg for spring force support of the clamping spring relative to the clamping leg. The invention also relates to a terminal having such a spring force clamping connection.

The invention discloses a preparation method of fiazonetin, and belongs to the technical field of medicinal chemistry. According to the route, a 3-methylpyrazine compound is used as a raw material, a compound 3 is obtained through an amine alkylation reaction or a condensation reaction, the compound 3 reacts with orthoester to obtain a compound 4, the compound 4 is subjected to a hydrogenation reduction reaction to obtain a compound 5, and the compound 5 is subjected to chiral resolution or chiral separation to obtain a compound 6. And carrying out condensation reaction on the compound 6 and p-fluorobenzoyl halide to obtain the non-azonepan. The raw materials are simple and easy to obtain, low in cost and more suitable for large-scale industrial production; according to the present invention, the route reaction is simple, the preparation efficiency is high, the yield of each reaction step can achieve about 90%, the ee value of the final product can achieve more than 99.0%, the chiral purity is high, no harsh reaction condition exists, and the method is suitable for large-scale production, and has good market value and profound practical significance. # imgabs0 #

The application discloses a multi-protocol conversion method, system, device and medium between fire alarm devices, and belongs to the technical field of communication; wherein the method comprises the following steps: S1, loading a protocol template; S2, establishing communication with a source device; S3, original data analysis and conversion; S4, data standardization writing into a database; S5, standardized data mapping and frame construction; S6, establishing communication with a target; the system comprises the following modules: a protocol configuration module, used for storing and managing template information of all converted protocols; a data acquisition and analysis engine, used for establishing communication with the source device; a data standardization and database module, used as a data transfer hub of the system; a data mapping and encapsulation engine, used for preparing communication data for the target device; and a data sending engine, used for communicating with the target device; the application solves the problems of protocol incompatibility between new and old fire alarm devices, lack of flexible conversion mechanism and difficulty in unified access to an Internet of Things platform in the prior art.

This invention relates to the field of backfill construction technology for building structures, and discloses a "sandwich" type anti-settlement construction method for high embankments in the first floor. The method includes: compacting the original soil in layers; pouring C15 plain concrete on the soil layers as a primary anti-settlement cushion layer and also serving as the foundation for the construction scaffold; after the scaffold is dismantled, pouring fluidized solidified soil with micro-expansion characteristics as a core "sandwich" layer to offset creep a second time, with a mix ratio of soil:solidifying agent:water = 10:1:3.5; and constructing C25 concrete with embedded steel mesh on the solidified soil as a tertiary anti-settlement cushion layer. This application can effectively control the settlement of high embankments through a "rigid-flexible-rigid" gradient reduction mechanism, utilizing the synergistic effect of multiple differentiated materials to ensure structural bearing capacity while avoiding the risk of ground cracking, realizing the resource utilization of waste soil, and significantly reducing construction and subsequent maintenance costs.

The invention discloses a zinc-doped high-toughness injectable organic-inorganic composite bioactive material and a preparation method thereof.The composite bioactive material comprises a water aqua and powder, the water aqua comprises water-soluble calcium salt, water-soluble phosphate, polyacrylic acid, polyaspartic acid, polyvinylpyrrolidone, citric acid and deionized water, and the powder comprises water-soluble calcium salt, water-soluble phosphate, polyacrylic acid, polyaspartic acid, polyvinylpyrrolidone, citric acid and deionized water. The powder comprises calcium hydrophosphate, tetracalcium phosphate and a zinc source. The zinc element is added, so that proliferation, differentiation and the like of osteoblasts are remarkably promoted, unexpected osteogenic activity is shown, all excellent mechanical properties in an existing bioactive material are completely reserved, and the properties include but not limited to coagulation time, compressive strength, toughness, injectability and the like; furthermore, the addition of zinc has no negative effects.

The invention provides a design method for preventing light leakage at the position of a screen camera hole of a blind hole screen, and relates to the technical field of wireless communication, and the method comprises the following steps: S1, preparing a backlight module; s2, arranging an iron frame at the position of a camera hole of the backlight module; s3, a circle of rubber frame is attached to the edge of the iron frame; s4, filling black glue, measuring a gap between the glue frame and the display glass, adjusting the amount of the black glue according to a measurement result, and uniformly filling the gap with the black glue; s5, the black glue is cured, and the backlight module is placed in a constant temperature box; according to the design, the black glue is accurately filled through automatic equipment, an additional glue dispensing procedure is avoided, the investment of materials and equipment is reduced, the overall cost is reduced, and the manufacturing process of the backlight module is accurately controlled, so that the durability of a product is improved, and the quality problem caused by light leakage is reduced; the expensive investment of dispensing equipment and the use of high-cost thermosetting adhesive are effectively avoided, so that manufacturers with small-batch production can also adopt the technology.

The present invention relates to an imine reductase or a mutant thereof and an application thereof in synthesizing a polycyclic chiral nitrogen heterocyclic compound, a method for synthesizing a polycyclic chiral nitrogen heterocyclic compound, and belongs to the field of enzyme engineering. The present invention provides an imine reductase IR-F7 mutant, which is a mutant obtained by mutation of a wild-type imine reductase IR-F7 with an amino acid sequence such as shown in SEQ ID No.1 as a parent. The present invention provides an application of an imine reductase IR-F7 or a mutant thereof, an imine reductase IR-B8 or a mutant thereof in synthesizing a polycyclic chiral nitrogen heterocyclic compound. The imine reductase or a mutant thereof of the present invention can catalyze intramolecular reductive amination, synthesize a polycyclic chiral nitrogen heterocyclic in one step, and avoid the use of expensive chiral reagents; by combining the DKR process, the raw materials can be fully utilized, no additional amino donor is required, and a good yield and selectivity are obtained; it has a wider substrate application range, and has more potential in the industrial application of synthesizing polycyclic chiral nitrogen heterocyclic compounds.

A disposable integrated endoscope integrates two light-emitting diodes (LEDs) and two complementary metal-oxide-semiconductor (CMOS) image sensors at the endoscope's tip. This not only avoids the use of expensive light guide prisms, making it a relatively low-cost, disposable integrated endoscope, but also provides clearer three-dimensional (3D) images of internal tissues or organs through the LEDs' light source. Furthermore, by incorporating a unique heat-conducting pipe cooling structure at the endoscope's tip, the high heat generated by the image sensors at the tip is rapidly conducted to the endoscope's rear end, achieving excellent heat dissipation and preventing the endoscope's tip temperature from exceeding 48°C and burning human tissue.

This utility model relates to the field of agricultural technology, specifically to a laser weeding machine, including a power supply, a mechanical mounting structure, a system main control unit, functional modules, a motor and its drive module. The functional modules are characterized by comprising a sub-control module, a characteristic spectrum storage chip, a spectrometer, a spectrometer light source, an optical path coupling module, and a laser. This utility model utilizes a right-angle prism to reflect the light emitted from the spectrometer light source and the laser from opposite directions, respectively. A stepper motor can precisely adjust the angle of the right-angle prism, ensuring that the two beams of light from the spectrometer light source and the laser can be focused on almost identical small areas. This improves the accuracy of beam positioning, enhances the reliability and efficiency of the system, and avoids the complex and expensive dichroic mirrors required in traditional laser weeding equipment, thus greatly simplifying the structure of the optical system and reducing production costs and technical implementation difficulties.

This invention discloses a method and system for rapid prediction of battery pack collision intrusion based on multi-fidelity data fusion. First, a training dataset containing high-fidelity and low-fidelity samples is constructed through finite element simulations with different mesh accuracies. Then, a two-level fusion model is established using Gaussian process regression. The predictions of the low-fidelity model are used as correction features to guide the high-fidelity model in accurate learning. Furthermore, based on an ensemble learning and Bayesian optimization framework, an improvement expectation criterion that incorporates simulation cost trade-offs is used for adaptive sampling. The location and accuracy level of newly added samples are intelligently determined, and the model is continuously optimized through iterative updates. This invention effectively resolves the contradiction between high-precision prediction and high computational cost, significantly reducing data acquisition overhead while ensuring prediction accuracy, providing an efficient and reliable technical means for battery pack collision safety assessment and optimization design.

This invention relates to a custom time-delay message processing method based on a distributed message queue, belonging to the field of distributed message queue technology. The method includes: a client receiving an arbitrary delay duration specified by the user, calculating a target Unix timestamp based on the client's current system time, and sending a message carrying that timestamp to a message broker layer; the message broker layer storing the message in a delay queue and inserting it into the corresponding time slot of a hierarchical circular time wheel according to the target Unix timestamp; the hierarchical circular time wheel consists of multiple levels of circular arrays, connected by an overflow mechanism; the message broker layer advances a global pointer at fixed time intervals, scans the messages to be scheduled in the time slots, and transfers expired messages from the delay queue to a regular queue for consumer consumption. This achieves flexible support for arbitrary delay durations and achieves task scheduling with O(1) time complexity through the hierarchical circular time wheel.

The invention discloses a preparation method and application of a heterostructure LDH / oxide electrolyzed water catalyst, and belongs to the field of electrocatalyst.The preparation method comprises the following steps that firstly, cut NF (1 cm * 1 cm * 0.7 mm) is subjected to ultrasonic cleaning with HCl, absolute ethyl alcohol and deionized water, then the cleaned NF is placed in a metal ion precursor solution (Fe < 3 + > and Ce < 3 + >), and the metal ion precursor solution (Fe < 3 + > and Ce < 3 + >) is obtained; dropwise adding a certain amount of hydrogen peroxide for reaction to obtain a product. The spherical NiFe-LDH-CeO2 heterostructure is prepared through a simple wet chemical etching method, the preparation process of the catalyst is simple, the cost is low, and an electrochemical test shows that the obtained catalyst is good in water electrolysis effect.

The invention discloses a suspension type maglev monorail high-speed train system, and belongs to the technical field of suspension type maglev rail transit. The system comprises a suspension type electromagnetic monorail subsystem and a vehicle-mounted permanent magnet suspension subsystem. The vehicle-mounted permanent magnet suspension rotor adopts a passageway type flexible rotor which is symmetrically arranged front and back and is formed by butting a traction permanent magnet rotor array and a magnetic suspension permanent magnet rotor array front and back, and a traction magnetic field passageway and a suspension magnetic field passageway are respectively formed; the suspension type electromagnetic monorail is embedded into the two passageways, and the functions of suspension, guiding and traction are integrated. The keel low-altitude channel is composed of a steel arch frame and a suspension long shaft, each suspension rail module can independently swing left and right, and the train automatically balances the gravity center when turning by being matched with the connection mode of a compartment and a bogie. The system has the advantages of simplified structure, low cost, high space utilization rate, strong wind resistance, high operation speed (more than 600km / h), no magnetic pollution risk and the like, has electromagnetic and mechanical two-stage redundant braking, and is safe and reliable.

The present invention relates to a tactile material classification method based on DDQN and generative adversarial network, which belongs to a tactile material classification method. The generative adversarial network GAN is trained using pictures and acceleration spectrum diagrams of tactile materials, and sent to the VGG19 network to extract features, the reward function of DDQN is set, the evaluation network of DDQN estimates the Q value, the global optimal solution is found, the trained network is saved, and the pictures are classified according to the action corresponding to the maximum Q value. The advantage is that the tactile information generated by the generative adversarial network GAN is used to classify tactile materials, which improves the noise resistance of the data. DDQN is used for classification problems for the first time, and the convolutional neural network VGG19 is introduced to process pictures, which avoids noise interference, ensures the robustness of the extracted features, avoids the complex tactile information collection process, saves the classification cost, and compared with the traditional classification CNN method, only a small time cost is used, the classification accuracy is improved, and the purchase of expensive tactile information collection equipment is avoided.

This invention provides a solution to disk space shortage based on object storage, comprising the following steps: dynamic disk expansion by adding data nodes until an odd number of data nodes are reached; building an NFS system using physical machines; interconnection between HBase and NFS; and data synchronization between the two NFS servers. The advantages of this invention are: cost savings, avoiding expensive physical machines; the ability to use older or inexpensive physical machines to run the NFS system; high data security, as this method does not compromise data security; dynamic expansion; and simple cold backup, as long as the data directory remains consistent, data services can be provided externally.

The invention discloses an asymmetric synthesis method of (R)-muscone, specifically, a novel chiral catalyst generated by coordination of a chiral ligand and a copper salt is used for catalyzing asymmetric synthesis of (R)-muscone, and the reaction selectivity and yield are both very high. According to the novel chiral catalyst, expensive metal is not used, and a satisfactory catalytic effect can be achieved by using a very low amount of chiral ligand, so that the production cost is greatly saved. The asymmetric synthesis method is simple in route and convenient to operate, and satisfactory selectivity and yield can be achieved without extremely low reaction temperature.

The invention discloses a chiral cyclophane molecule BinapoBox.4PF6 as well as a preparation method and application thereof, belongs to the field of macrocyclic molecule research, and particularly relates to a chiral cyclophane molecule as well as a preparation method and application thereof. The invention aims to solve the problems that the existing chiral aromatic dye is high in synthesis cost and the process of inducing an achiral compound to generate chirality is complicated. The structural general formula of the chiral cyclophane molecule BinapoBox. 4PF6 disclosed by the invention is C92H70F24N4O2P6, and the structural general formula is shown in the description. The chiral cyclophane molecule BinapoBox.4PF6 and the aromatic dye have excellent binding capacity and special fluorescent property, so that the chiral cyclophane molecule BinapoBox.4PF6 becomes a good chiral host material for preparing a chiral host-achiral object assembly (CPL) material. The complex synthesis modification is avoided, the expensive liquid crystal material is also avoided, and the cost can be greatly reduced by amplifying equivalent batch preparation. The chiral cyclophane molecule disclosed by the invention is a novel chiral cyclophane product which can be recycled and has universality.