The invention relates to a depth domain velocity modeling method for piedmont zone seismic data processing. The method comprises the following steps: 1) velocity constrained inversion is used for local single point control on a prestack time migration root mean square velocity, a time domain layer velocity is converted through a DIX formula, time-depth conversion is then carried out, a depth domain layer velocity volume is obtained and is subjected to smoothing, and a prestack depth migration depth domain initial layer velocity model is obtained; 2) grid chromatography inversion optimization is carried out on a velocity model; 3) the optimized velocity model is used for carrying out prestack depth migration on all data in a work area, a depth domain stacked data volume is obtained, the depth domain stacked data volume can be scaled to the time domain, structural interpretation is carried out on the time domain, and a structural model is obtained; and 4) borehole restraint is used for carrying out chromatography inversion optimization on the structural model. Thus, the piedmont zone high-steep structure depth migration imaging processing depth domain velocity model precision is improved, the piedmont zone high-steep structure migration precision is higher, and the well-to-seismic coincidence degree is improved.