The invention relates to a casing-harmonic-containing vertical seismic profile data interval velocity inversion method. The method is used for suppressing casing harmonics by low-pass filtering and F-K filtering in seismic prospection, and includes steps of obtaining amplitude spectrums by means of 15-Hz low-pass filtering, obtaining F-K spectrums by converting the amplitude spectrums in a track direction, clearing all F-K spectrums of up-going waves and down-going waves of the speed higher than 5000 m/s, obtaining a second wave field of time domain by means of inverse Fourier transform, picking a continuous event from the down-going waves of the wave field to obtain first break I of each track, picking the first break on an original interference-less track and translating the same, obtaining the first break II by adding the first break I of each track with the translation value, obtaining the adjacent difference by subtracting the depth of the previous track from the depth of the next track, obtaining the first break difference of the adjacent track by subtracting the record first break of the first track from the record first break II of the next track, and finally dividing the depth difference of the adjacent track by the first break different of the adjacent track. By the method, interference to the interval velocity from the casing harmonics can be avoided, so that accurate first break and interval velocity are acquired. Accordingly, the method is easy and convenient to use, and high in computational efficiency.