The invention discloses an intra-tube forming machine of a sputum-suction drainage tube or a urethral catheter. The intra-tube forming machine comprises a rack, a feeding box, a grabbing and carrying assembly, a heating and necking-down assembly, a notching assembly and a transmission assembly, wherein a plurality of drainage tubes are clamped by a clamp to form a drainage tube assembly; the drainage tube assembly is lifted up to an opening face of the feeding box from a material box inside the feeding box through a lifting mechanism, then is moved onto a synchronous belt of the transmission assembly in an upgrade and degrade manner through a sucking claw assembly, is transmitted to the heating and necking-down assembly through the transmission assembly, and is positioned by a clamping and positioning assembly, then one end of the drainage tube assembly is subjected to heating and necking-down operation by the heating and necking-down assembly, the heated drainage tube assembly is transmitted to the notching assembly through the synchronous belt, then, the necking-down end of the drainage tube assembly is trimmed by the notching assembly, and the drainage tube assembly is sent to a discharging hole by a discharging and grabbing assembly. According to the invention, mechanical production and processing equipment is adopted to meet the requirements of mechanical and automatic processing and production, so that the production and processing efficiency is improved, in addition, the transmission assembly is used to enable the equipment to realize streamlined production and processing operation truly, so that, the investment cost is reduced, and meanwhile, the reject ratio is reduced.