A cartridge box of a pneumatic toy gun includes an air lock system and a struck element disposed on the upper inside the case of the cartridge box, and further includes a control system having a pushing rod and a resisting rod, wherein a front end of the pushing rod extends into the bullet-out passage disposed inside the case. When there is no bullet in the bullet-out passage, a lateral end of the stripping rod resists upward against the front end of the pushing rod to make the back end of the resisting rod moving downward to resist against the resisting portion of the struck element, resulting that the struck element cannot push the air lock system forward. Thereby, when there is no bullet in the cartridge box, even if the trigger is pressed, the air lock system cannot moves to push the bolt. Hence, firing without bullet will be avoided and the effects of the simulate gun would be achieved. The cartridge box further has a turning system having a turning portion with a cam portion, which is turned upward to resist against the resisting rod, resulting that the resisting rod moves away from the resisting portion of the struck element. Thereby the bolt can be pushed to make a fire without bullet.