The invention provides an inpatient ward disinfecting machine, which is composed of a high pressure generator (1), a central control room (2), a control circuit (3), a high-voltage positive electrode(4), a high-voltage electrode discharge needle (5), a high-voltage negative electrode conducting cylinder (6), a positioning buckle bolt (7), a substrate (8), a high-voltage negative electrode contactelastic piece (9), a positive electrode discharging needle fixing nut (10), an axial flow fan (11), a high-voltage positive electrode substrate (12), an insulation isolating layer (13), a box body reinforcing rib (14), a tubular type exhaust fan (15), a working displayer controller (16), and a safety shutter (17), and others; the inpatient ward disinfecting machine is characterized in that air enters from the substrate (8) to an air ionization chamber consisting of the high-voltage negative electrode conducting cylinder (6) and the high-voltage electrode discharge needle (5) for ionization, and then poisonous and harmful gases are decomposed by ionization, powder and impurities are captured on the high-voltage negative electrode conducting cylinder (6), thus the purposes of purifying, filtering, refreshing and disinfecting air are realized.