The invention discloses an unmanned self-help selling vehicle. The technical problem that the current self-help selling vehicle has the single function can be solved. The unmanned self-help selling vehicle comprises a vehicle body. The vehicle body is provided with a plurality of storage cabinets. The vehicle body further comprises a management system, a GPRS module, a video monitoring module, an entrance guard system, an alarm module, an unmanned driving module, and an automatic storage module, and further comprises a server and an APP module. The GPRS module, the video monitoring module, the entrance guard system, the alarm module, the APP module, the automatic storage module and the unmanned driving module are in the communication connection with the management system. The server is in the communication connection with the APP module and the management system. The unmanned self-help selling vehicle is not limited by time and place, the labor force is saved, the transaction is convenient, and the great convenience is provided for the current living.