108results about How to "Additional movement" patented technology

This invention provides a small diameter snare device and device for thrombus removal consisting of a hollow, elongate, thin-walled outer sheath. A single central core wire extends through the entire length of the sheath. The outer diameter of the core wire is sized close to the inner diameter of the sheath while allowing for axial sliding, in order to maximize the support to the body portion of the snare device. A tool tip or “capture segment” at the distal end of the sheath and core wire can be controllably expanded to engage a thrombus and remove the thrombus from the blood vessel.

This invention provides a small diameter snare device and device for thrombus removal consisting of a hollow, elongate, thin-walled outer sheath constructed from polymer, at least at a distal part thereof. A single central core wire extends through the entire length of the sheath. The outer diameter of the core wire is sized close to the inner diameter of the sheath while allowing for axial sliding, in order to maximize the support to the body portion of the snare device. The distal end of the core wire has a tapered section of reduced diameter or cross section to provide a “guidewire-like” flexibility to the distal portion of the device. A second wire (or wires) of about fifty percent or less of the inner diameter of the sheath is (are) shaped to form a snare loop or radially extended tool tip that is attached to the distal most portion of the central core wire. The snare loop is typically circular or oval shaped and can also be multiplanar (for example, a twisted, figure eight shape) so as to increase the ability to ensnare and capture objects. The tool tip can be a planar or multi-planar, proximally directed structure that, when deployed, is adapted to engage the thrombus from behind after piercing the thrombus with the sheath while the tool tip is retracted.

A foot pedal control for a surgical system (e.g., an ophthalmic surgery system) that adjusts to a number of different sizes of user's shoes. The foot pedal control has a treadle on which a user places his or her foot and a sensor that tracks the movements thereof. Adjustable lateral guides mount to the treadle and conform to both sides of the foot. The guides are shaped and positioned to conform to a wide variety of feet or shoes, and may easily be adjusted between users. A retractable heel stop converts between up for reference and down to enhance movement of the user's foot. A convertible handle may be stowed in a down position parallel to a base or pivoted up over the treadle for protection and ease of movement of the foot pedal control. The foot pedal control may be wireless and have various other electronic controls, and may have a dual-control treadle.

The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.

The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.

An internal device for use in an underwater cable may comprise a body having an outer periphery, body being mountable inside the cable with the cable surrounding the outer periphery of the body. The body may include a cutaway portion, a slot, or a dovetail joint. An underwater cable arrangement may comprise an underwater cable and an internal device disposed in the cable with the cable surrounding the device. The underwater cable may include a stress member connected to the internal device by an interference fit or the internal device may include a slot for receiving the stress member. A method of connecting a stress member of an under water cable to an internal device includes forming an interference fit between a region of increased diameter of the stress member and the internal device.

This invention provides a small diameter snare device consisting of a hollow, elongate, thin-walled polymer outer sheath. A single central core wire extends through the entire length of the sheath. The outer diameter of the core wire is sized close to the inner diameter of the sheath while allowing for axial sliding, in order to maximize the support to the body portion of the snare device. The distal end of the core wire has a tapered section of reduced diameter or cross section to provide a “guidewire-like” flexibility to the distal portion of the device. A second wire of about fifty percent of the inner diameter of the sheath is shaped to form a snare loop and the two ends are attached to the distal most portion of the central core wire via welding, soldering, or brazing. After assembly of the core and sheath, a second short, hollow tube is fitted over the proximal end of the central core and attached thereto to provide an actuating handle to slideably move the central core within the sheath, thus exposing and retracting the snare loop from the open distal end of the sheath. The loop is typically circular or oval shaped and can also be multiplanar (for example, a twisted, figure eight shape) so as to increase the ability to ensnare and capture objects. The loop attachment to the core wire is facilitated and strengthened by a wrapped coupling coil formed typically of 0.001-inch platinum wire applied to secure the loop prior to soldering (brazing or other metal-flowing joining techniques), and through which solder flows to permanently secure the loop to the core wire.

The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.

Devices, systems, and methods for positioning an end effector or remote center of a manipulator arm by floating a first set of joints within a null-perpendicular joint velocity sub-space and providing a desired state or movement of a proximal portion of a manipulator arm concurrent with end effector positioning by driving a second set of joints within a null-space orthogonal to the null-perpendicular space. Methods include floating a first set of joints within a null-perpendicular space to allow manual positioning of one or both of a remote center or end effector position within a work space and driving a second set of joints according to an auxiliary movement calculated within a null-space according to a desired state or movement of the manipulator arm during the floating of the joints. Various configurations for devices and systems utilizing such methods are provided herein.

Devices, systems, and methods for positioning an end effector or remote center of a manipulator arm by floating a first set of joints within a null-perpendicular joint velocity sub-space and providing a desired state or movement of a proximal portion of a manipulator arm concurrent with end effector positioning by driving a second set of joints within a null-space orthogonal to the null-perpendicular space. Methods include floating a first set of joints within a null-perpendicular space to allow manual positioning of one or both of a remote center or end effector position within a work space and driving a second set of joints according to an auxiliary movement calculated within a null-space according to a desired state or movement of the manipulator arm during the floating of the joints. Various configurations for devices and systems utilizing such methods are provided herein.

A toothbrush (10) is disclosed with soft fingers (16) mounted on the toothbrush head (14). During use of the tooth-brush the fingers move laterally relative to the axis of the tooth-brush thereby improving the tooth cleaning and gum massaging performance of the toothbrush. The lateral movement of the fingers is accomplished by relatively stiff ribs (24) which physically interconnect the fingers to flexible portions of the toothbrush head. The ribs translate flexure of the head into the lateral movement of the fingers.

A transition duct assembly with a thermally free aft frame and mounting system for use in a gas turbine engine are disclosed. The aft frame is capable of adjusting to thermal gradients while the mounting system provides for at least transverse movement of the transition duct during engine assembly. The mounting system also provides a means for raising the natural frequency of the transition duct outside of the engine's dynamic excitation ranges.

There is provided a method for controlling the movement of bile and / or gall stones in the biliary duct. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the movement of bile and / or gallstones in the biliary duct, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the movement of bile and / or gallstones in the biliary duct. The method can be used for restricting or stopping the movement of bile and / or gallstones in the biliary duct, or for actively moving the fluid in the biliary duct, with a low risk of injuring the biliary duct.

A locking mechanism configured to prevent rocking motion of a seat of a rocking and reclining chair relative to a base of the chair when the chair is in a reclined position, the locking mechanism being interconnected with the base and with a reclining mechanism of the chair, includes: a drive link adapted to be pivotally interconnected with the reclining mechanism; a control link adapted to be pivotally interconnected with the base and having a slot; and a bracing link pivotally interconnected with the drive link and slidably and pivotally interconnected with the control link via a pin inserted into the control link slot, the bracing link including a wheel at an engagement end thereof. The locking mechanism is configured to be movable between a retracted position, in which the engagement end of the bracing link does not engage the base to prevent rocking motion of the chair, and an extended position, in which the engagement end of the bracing link engages a bearing surface of the base to prevent rocking movement of the chair.

A method and apparatus are provided for thawing and heating biological material such as plasma, bone marrow or stem cells. The apparatus includes a housing containing a fluid-filled, sealed bladder for receiving a bag of the biological material. An agitator is provided which is operable to inflate an actuator pillow causing a support plate to compress the fluid-filled bladder, thereby promoting movement of the fluid within the bladder to agitate the biological material. A heater is provided which heats the fluid while contained in the bladder.

The present invention introduces a radically different way of accelerating biomolecule conjugates into tissue, and hence towards their targets for purposes of tissue staining. The invention provides for an order of magnitude improvement over the prior art diffusion process used to stain tissue. The invention comprises a method of tissue staining by applying an electric field to a tissue sample in the presence of an electrolyte and biomolecular conjugates of interest suspended in the electrolyte. Typical staining times are reduced to seconds as opposed to 30-120 minutes common in the prior art. The invention is also directed to devices for performing the method.

An apparatus and method for an exercise apparatus is disclosed that includes a base structure, a multiple axes pivotal mechanism disposed adjacent to the base structure, and an arm. The arm further includes a distal end portion and a proximal end portion with a longitudinal axis spanning therebetween. The distal and proximal end portions are each adapted to provide independent resistive force to muscle exertion, with the proximal end portion being adjacent to the mechanism such that operationally at least two independent axes of movement occur in the arm relative to the structure. Also included in the exercise apparatus is an assemblage for creating selectable variable resistance forces to the movement of the arm relative to the structure, such that each axis of movement has an independent selectable variable resistance force to the arm movement.

Molding material consisting of resin coated reinforcing fiber strands in a molten mass of resin is prepared at a molding site for controlled supply to a molding machine. Continuous strands of fiber from supply spools are entrained with pressurized, molten resin flowing through a coating device and coated with the resin. The movement of the fiber and resin through the coating die may be controlled so as to accurately and predictably produce any desired quantity the molding material, i.e. the coating apparatus may be operated in a discontinuous manner to provide any predetermined quantity of molding material to a receiving device. The receiving device may be the feed screw for an injection molding machine or simply a plate movable to and from a compression molding machine. The fiber strands may be cut into predetermined lengths by a cutting device positioned downstream of the aforesaid coating device.

Disclosed is a system for providing in vivo delivery of molecules or complexes to extravascular mammalian cells using an intravascular administration route. The molecules or complexes are inserted in an injection solution into a mammalian vasculature. Insertion of the injection solution at an appropriate rate transiently increases the volume of extravascular fluid in the tissue thereby facilitating delivery of the molecule to the cell.

Topical drug delivery formulations with optical amounts of vasodilator. Vasodilator chemicals applied topically dilate the blood vessels in the skin tissue, which have been shown to facilitate or inhibit systemic or skin tissue deposition of drug substances. The level of stimulation and / or inhibition has been found to be dependent on the concentration and the identity of the specific vasodilator chemical(s) used as well as the drug molecule(s) to be delivered. This work teaches the need to consider specific formulation requirements when dealing with vasodilator chemicals for the creation of successful delivery vehicles in the transdermal drug delivery system. These requirements for very low concentrations of vasodilators were an unexpected and a surprise finding, in contrast to the concentrations of the vasodilators typically used to elicit an increase in skin blood flow.

A tubular coupling comprising a female connector (2) into which a male connector (6) provided with an annular collar (7) is designed to be inserted axially, and a connection element (9) that extends in a transverse direction in the female connector. The connection element is designed to interfere mechanically with the collar while the male connector is being inserted into the female connector, and to move by itself in said transverse direction towards the inside of the female connector. In addition, the connection element and the female connector are also designed so that, after the reaction to the radial resilient deformation of the connection element on the collar of the male connector, they come to bear against each other in the manner of a projection (14) that, by resilient return, exerts pressure on a guide ramp (15), so as to generate a thrust force that extends the movement of the connection element towards the inside of the female connector.

A device for sorting railroad tie plates comprises hopper, singulator and chute assemblies mounted to a main frame capable of rolling movement along a railroad track. The device receives a plurality of tie plates from an upstream supply, e.g., a railroad gondola, and deposits the tie plates on the hopper assembly positioned above the singulator. Upon discharge from the hopper the tie plates are directed onto a central hub for guidance into a rotating track within the housing. The track width is selected so that the field and gage ends transverse the track upon the tie plates falling flat onto the track. Structure projects into the track to tip over the tie plates to a flat position during track rotation. Rotation of the track moves the tie plates towards a baffled opening for discharge from the opening. A chute assembly receives the tie plates and maintains the tie plate orientation for delivery to downstream devices, such as a conveyor belt. Upon rolling movement of the main frame tie plates are sequentially deposited along the course of the railroad track to enhance railroad track maintenance.

An apparatus includes a printing unit and a drying unit. The printing unit performs printing on a sheet using ink. The drying unit dries the sheet on which the ink is applied at the printing unit as the sheet is conveyed in the drying unit. The drying unit causes hot air heated by a heater to circulate through a housing and blows the hot air to the sheet. The housing includes an opening through which movement of gas between inside and outside the housing can be adjusted. When conveyance of the sheet in the drying unit stops, the apparatus is controlled to reduce an output of the heater and to increase the movement of the gas through the opening.

A transition duct assembly with a thermally free aft frame and mounting system for use in a gas turbine engine are disclosed. The aft frame is capable of adjusting to thermal gradients while the mounting system provides for at least transverse movement of the transition duct during engine assembly. The mounting system also provides a means for raising the natural frequency of the transition duct outside of the engine's dynamic excitation ranges.

A tubular conveyor for conveying grain or seed includes an intake end having a first roller and a discharge end having a second roller. A tubular portion is disposed between the intake end and the discharge end. A continuous flexible conveyor belt is coupled with the first and second rollers. Seal means are provided for sealing edges of the conveyor belt at a point approximately where the conveyor belt meets at least one of the first and second rollers.