The invention provides a nuclear power station diversity protective system hardware architecture based on field programmable gate array (FPGA), aims at solving the technical problem to avoid potential risks caused by software common mode failure, and belongs to the industrial automatic control field. The architecture is characterized in that a card piece comprises an analogy quantity input card, a logical processing card, a digital quantity input/output card and a communication card, the card piece respectively uses the FPGA as a logical processing component, the analogy quantity input card and the digital quantity input/output card respectively carry out data transmission through a signal transmission line and the logical processing card, and the analogy quantity input card, the digital quantity input/output card, the logical processing card, an upper computer and display equipment respectively carry out the data transmission through the signal transmission line and the communication card. The architecture solves the problem of the potential risks brought about by the software common mode failure, and improves reliability of a nuclear power station instrument control system. Simultaneously, self diagnosis, real-time monitor, parameter setting and online channel test of the card piece can be carried out, and flexible card piece arrangement can ensure expandability and integrity of a whole hardware platform.