35 results about "Noise-induced hearing loss" patented technology

Devices and methods for digital sound leveling are disclosed. The subject devices and methods can be used to reduce the risk of noise induced hearing loss. According to an embodiment, an audio file can be parsed into frames that are filtered using an A-weighted digital filter and scaled to a desired power level. Accordingly, the dynamic range of an audio output at a particular volume level can be controlled.

An apparatus is disclosed for managing the joint contribution of noise exposure of the ear of a user of the apparatus from a loudspeaker of the apparatus as well as from ambient noise so that the risk of risk of noise induced hearing losses is reduced. By assessing the joint actual sound energy delivered to the ear and feeding said assessment to a model describing the accumulated risk of hearing loss due to said sound energy accumulated over a time period, an estimate of the current risk of hearing loss is obtained. When said risk estimate passes a predetermined threshold, one or more protective measures are taken.

A sound monitoring control for controlling the sound pressure level (SPL) delivered to the ears of a user of a hearing protection device. The control employs a measurement of the actual sound heard by the user, using a microphone to control the sound level and to help prevent noise induced hearing loss. A measurement, using a dosimeter microphone, of the actual sound pressure levels heard by the user can be used in audio processing schemes to ensure that the user is only exposed to safe levels.

A method of avoiding harmful noise levels, the method comprising implementing a cognitive suite of workplace hygiene and injury predictors (WHIP) that has learned to identify noise sources and indicators of harmful noise levels, detecting an indicator, and implementing a corrective action by at least one of altering the operation of a noise source, modifying a time of a scheduled task, or changing prescribed personal protective equipment.

The invention discloses a drug or health care product for preventing and treating hearing loss and relates to the technical field of biological medicine and health care products. Aiming at the defects that there are not many drugs for treating hearing loss in the market currently, the treatment effect is poor, and health care products with the corresponding function are unavailable, the effective and well-targeted drug for preventing and treating hearing loss and the corresponding health care product, especially the drug which has a special effect on sensorineural hearing loss including age-related hearing loss, noise induced hearing loss and sudden hearing loss and the corresponding health care product are provided. The drug or health care product contains the active constituent nicotinamide mononucleotide. The drug or health care product has the advantages of being capable of becoming effective quickly, high in treatment effect, stable in efficacy, free of toxic or side effect on human body and the like.

Ototoxic side-effects have either limited the application of an important group of antibiotics, aminoglycoside antibiotics, or have added further burden to those who have to resort to platinum-containing antineoplastic agents to treat life-threatening tumors. The present invention discloses pharmaceutical compositions that prevent or treat the ototoxic side-effects of aminoglycoside antibiotics and platinum-containing antineoplastic agents. The otoprotective compositions disclosed herein can also be used to treat noise induced hearing loss.

The invention discloses a nutritional agent with noise reduced hearing loss resistance. The nutritional agent is prepared from the following raw materials in parts by weight: 600-1000 parts of N-acetyl-L-cysteine, 1-4 parts of vitamin A, 1-5 parts of vitamin B1, 1-5 parts of vitamin B2, 1-10 parts of vitamin B6, 0.01-0.05 part of vitamin B12, 60-1000 parts of vitamin C, 15-300 parts of vitamin E which is based on alpha-totaxin, 50-400 parts of magnesium and 79-3175 parts of food acceptable accessories. Experiment data displays that the nutritional agent has remarkable effect of preventing and controlling the noise induced hearing loss. The nutritional agent can be used for enhancing the anti-oxidation ability of the organism and lightening the exitotoxicity damage, has the characteristics of being remarkable in curative effect, low in potential toxicity and low in cost, and is suitable for the noise reduced hearing loss protection and daily nutrient supplementation of people who live and work in the environment with continuous exposed high-intensity noise.

A method for treating noise-induced hearing loss (NIHL) includes the step administering a composition to the mammal, wherein the composition consists essentially of a biologically effective amount of vitamin A, vitamin E, vitamin C, a vasodilator comprising magnesium, and, optionally, a withanolide, and/or resveratrol.

The invention relates to a method and kit for detecting an SNP (Single Nucleotide Polymorphism) site rs10081191 of a susceptible gene region 7q36.3 related to a disease risk of NIHL (Noise Induced Hearing Loss), and application. The method is Sequenom typing. The invention further relates to the kit for detecting the susceptible site and application of the kit. In addition, the SNP site rs10081191of the region 7q36.3 is associated with the disease risk of the NIHL, and the invention discloses the SNP and application thereof. The SNP is located in a human genome region 7q36.3, the 7q36.3 is determined to be a new susceptible gene region of the NIHL, and the SNP can be effectively used for screening susceptible groups of the noise induced hearing loss diseases and determining susceptible individuals of the noise induced hearing loss diseases.

The present invention provides methods of preventing, treating, and/or reducing noise induced hearing loss and/or noise-induced inner ear trauma. The methods include the administration of glatiramer acetate or a derivative thereof and, optionally, at least one anti-oxidant.

The invention discloses an application of Riviciclib hydrochloride (p276-00) in preparation of a medicine for preventing and treating noise induced hearing loss, relates to the field of medicines, and aims to solve the problem that existing medicines for preventing and treating noise induced hearing loss are rare. According to the invention, with the application of the noise induced hearing loss animal model experiment method, the hearing, the internal hair cell function and the like of the mouse after the noise exposure are detected, it is found that the Riviciclib hydrochloride (p276-00) has the good protection effect on the number and the function of the internal hair cell synapses during the noise exposure, the prevention and treatment effect of the Riviciclib hydrochloride (p276-00) on the noise induced hearing loss is directly verified, and the Riviciclib hydrochloride (p276-00) can be used for preparing the medicines for preventing and treating the noise induced hearing loss and has good research and application prospects.

The present invention relates to a pharmaceutical composition for preventing or treating hearing loss, containing cilostazol and a ginkgo leaf extract as active ingredients. The pharmaceutical composition can effectively prevent or treat noise-induced hearing loss or ototoxic hearing loss by inhibiting the apoptosis of hair cells due to the generation of reactive oxygen species (ROS).