The invention discloses individualized voice collection and semantics determination system and method. The individualized voice acquisition and semantics determination system comprises a voice collection module, a voice unit module, a voice database, a semantics database, a voice correspondence semantics database, a semantics normalization module and a voice correspondence standard semantics database, wherein the voice collection module collects voice sound from the vocal organ of a sounder; the voice unit module classifies the voices collected by the voice collection module and establishes voice units by using monosyllables, bisyllables and multisyllables; the voice database is established by using the voice units as basic units; and the voice correspondence semantics database is established by corresponding the voice units of the voice database to the semantics database in one-to-one way. In the invention, the sounder directly determines the correspondence between voices and semantics text words, no requirement is asked for the sounder, the sounder does not need to be trained, the system does not need to be trained neither, and the accuracy is 99.9%.