3results about How to "Low ecotoxicity" patented technology

This invention discloses a method for preparing and applying an antibacterial composite coating based on quaternized zinc oxide nanoparticles. The preparation method includes: grafting quaternary ammonium salt compounds onto the surface of zinc oxide nanoparticles to prepare synergistic antibacterial nanoparticles; modifying the substrate surface by co-deposition of dopamine and polyethyleneimine to introduce active functional groups; and spraying or dipping the quaternized zinc oxide nanoparticles onto the modified substrate surface to obtain the antibacterial composite coating. This novel antibacterial material preparation scheme can integrate the advantages of zinc oxide nanoparticles and quaternary ammonium salts, while solving key technical problems such as nanoparticle aggregation, weak interfacial bonding, and limited antibacterial efficiency. It is of great significance for promoting the upgrading of hygiene and safety in the fields of medicine, food, and building materials.

The application provides an ethanol-mediated linear RNA-lipid nanoparticle demulsification method, comprising the following steps: performing three demulsifications on an mRNA-lipid nanoparticle sample with an ethanol solution to obtain mRNA precipitation; the concentration of the ethanol solution is 85wt%-90wt%, and the ethanol solution used in each demulsification is reduced in the three demulsifications. The technical scheme of the application significantly reduces the ecological toxicity, is safer, improves the mRNA recovery rate and purity, and can maximize the integrity of the mRNA. In addition, the method is simple to operate, does not require complex experimental operations and special equipment, reduces the operation difficulty and time cost, improves the experimental and production efficiency, and has a wide application prospect.

This application provides a bio-based chain extender and its application. The bio-based chain extender includes the bio-based compounds 2,5-furandicarboxaldehyde dioxime and / or 5-hydroxymethyl-2-furancarboxaldehyde dioxime. Using these as bio-based chain extenders, modified polyurethanes with antibacterial and antifungal properties can be synthesized. This imparts long-lasting, stable, and broad-spectrum antibacterial and antifungal properties to polyurethane materials, eliminating the need for additional antibacterial agents. This avoids problems such as environmental pollution, short antibacterial time, and unstable antibacterial performance caused by antibacterial agent migration during the use of polyurethane materials. In particular, this bio-based chain extender is bio-based, safe, and environmentally friendly, and has a significant effect on the antibacterial and antifungal modification of polyurethane materials, showing broad application prospects in medical materials, public facilities, and health protection.