The invention discloses a high-gain isolated-type active clamping soft-switched DC-DC convertor, and belongs to the technical field of convertors. The convertor comprises a current multiplication loop, a transformer and a switched capacitance loop; the current multiplication loop comprises a voltage source Vin, two input inductors L1 and L2, a clamping capacitor Cc, two main power switch tubes S2 and S4, two auxiliary power switch tubes S1 and S3, external capacitors CS1, CS2, CS3 and CS4 of the four power switch tubes S1-S4, and a transformer primary coil shunt inductor L; the switched capacitance loop comprises four rectifier diodes which include D1, D2, D3 and D4, one resonance inductor Llk, two resonant capacitors C11 and C12, two output capacitors C21 and C22, and a load resistor R. The high-gain isolated-type active clamping soft-switched DC-DC convertor has the advantages of having high gain, being small in ripple of input current, small in ripple of output voltage, low in cost, and high in efficiency, and can be applied to occasions of conversion from direct current to direct current in low-voltage and large-current systems like a photovoltaic power generation system and a fuel-cell power generation system.