The invention discloses a battery module and a manufacturing method. The battery module mainly comprises batteries, vertical columns, end plates and lateral plates, wherein the vertical columns are fixed and limited to the end plates through tenon-and-mortise structures in advance, and the vertical columns are tightly installed on the end plate through bolts; the vertical columns are used for fixing at least one of a tray on the upper layer and a top plate on the lower layer. Because the tenon-and-mortise structures are adopted between the vertical columns and the end plates, the problem thatin the prior art, when placed, the vertical columns cannot be pre-fixed is solved, great convenience is brought to subsequent assembly, the calibration time is reduced during installation, and the PACK efficiency is effectively improved. Liquid cooling system installation grooves are reserved in the end plates, and a liquid cooling system is conveniently designed. Wire binding holes used for fixing a wire group and mortise holes used for connection are formed in the surface of the module. Lateral plate connecting grooves are reserved in the lateral sides of the end plates of the modules, and after being bent, the lateral plates of the module can be connected with the end plates of the module so that a shell of the module can bear larger battery swelling force.