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Modular distributed cryogenic system
A modular distributed cryogenic distribution system, comprising: a common chamber housing cryogenic fluid conduits; and a plurality of cryochambers connected to the common chamber. A method of operating a modular distributed cryogenic distribution system comprising a common chamber housing cryogenic fluid conduits, and plural cryochambers connected to the common chamber, includes raising one the plurality of cryochambers room temperature while a second one of the plurality of cryochambers operates at a cryogenic temperature.
Owner:PSIQUANTUM CORP
Systems, apparatus and methods to pick and / or place specimen containers
ActiveUS12527318B2Lighting and heating apparatusStationary refrigeration devicesControl systemHydrology
A system, device and method to pick and / or place specimen containers may include a pick and / or place head, a first secondary reservoir, and optionally a second secondary reservoir which hold cryogenic fluid in a liquid form, above a main reservoir of cryogenic liquid, to cool the pick and / or place head and / or to cool or recharge the specimen containers during transfer operations. Storage locations may be arrayed in wedge-shaped sets spaced above cryogenic liquid of the main reservoir of a cryogenic storage tank at one or more levels, and pivotal about a central axis via a motor and control system. A gap (e.g., wedge shaped gap) between two successively angularly adjacent sets of storage locations of the sets of storage locations at an upper level provides access to the storage locations of the sets of storage locations at a lower level. Cryogenic liquid temperatures and levels in reservoirs are monitored.
Owner:TMRW LIFE SCIENCES INC
Defrost fan control
A refrigeration module of a cold space chamber has a blower and an evaporator. A method of controlling the refrigeration module includes defrosting a coil of the evaporator to form a volume of warm air surrounding the coil. The method includes circulating a refrigerant through the evaporator after defrosting the coil, to cool the coil. The method includes operating the blower in a series of pulses to control introduction of the volume of warm air into the cold space chamber.
Owner:TRANE TECHNOLOGIES LIFE SCIENCES LLC
Systems, devices, and methods for automated thawing of bag-format storage vessels
The present invention discloses sample thawing devices, systems, and methods, that are configured to take bag-format sample vessels, referred to as “cryobags”, and to thaw the contents of such cryobags. The contents of such cryobags are samples with cells, and the thawing of such samples is based on the temperature, volume, and mass of the sample in order to evenly distribute heat and avoid ice crystallization damage to the cells during thawing. Paired heater plates form an assembly configured to support, clamp, and thaw individual cryobags. The heater plate pair has an articulated member that is repositioning to provide for ease in inserting and removing samples.
Owner:BIOLIFE SOLUTIONS INC
A module for a freeze-dryer system, a freeze-dryer system and a method for using the system
PCT designated stageWO2025158039A1Drying solid materials with heatDrying solid materials without heatFreeze-dryingControl cell
The present invention is related to a sample heat exchanger module (200) for a freeze-dryer system (100) comprising - a first heat exchange element (201) made of thermally conductive material and comprising • a top surface (202); and • a plurality of straight passages (203, 204, 205) extending in different directions through the first heat exchange element (201), the passages being parallel to the top surface (202) and intersecting at the interior of the first heat exchange element (201); - a first cold source (206) comprising a cold end (207) with a maximum efficiency zone (208) that is in thermal contact with the first heat exchange element (201); and - a first heat source (209) comprising a maximum efficiency zone (210) in thermal contact with the first heat exchange element (201); wherein the straight passages (203, 204, 205) are arranged between the top surface (202) and the maximum efficiency zones (208, 210) of the first cold source (206) and the first heat source (209), and wherein the first cold source (206) and the first heat source (209) are controllable by a control unit (102) to decrease or increase the temperature of the first heat exchange element (201).
Owner:300K SOLUTIONS SL
Rapid-cooling, temperature-intensive cryogenic test chamber allowing for relative motion
PendingUS20250283792A1Preparing sample for investigationMaterial strength using tensile/compressive forcesTest chamberRelative motion
A cryogenic testing apparatus includes a housing in which a cryogenic chamber is positioned. An upper channel is arranged around the cryogenic chamber and is configured to receive a cryogen. A lower channel is arranged below the upper channel and is configured to receive cryogen from the upper channel. As the cryogen flows through the cryogenic testing apparatus, the cryogen contacts an exterior of the cryogenic chamber. The cryogenic chamber is unsealed and is configured to receive a gas to create positive pressure within the cryogenic chamber.
Owner:TEXAS A&M UNIVERSITY +1
Accommodation apparatus for freezing target
To increase the quantity of freezing targets stored in a storage space of a freezing container. A first accommodation unit 10 accommodating a first freezing target 91 includes a first female screw member 16a to which a part of a shaft member 80A is detachably coupled. A second accommodation unit 20 accommodating a second freezing target 92 includes a second female screw member 26a to which a part of the shaft member 80A is detachably coupled, and is arranged above the first accommodation unit 10 in a state of being stored in a freezing container 300. In a state where the second accommodation unit 20 is arranged above the first accommodation unit 10, the shaft member 80A is coupled to the first female screw member 16a to take out the first accommodation unit 10 and the second accommodation unit 20 collectively.
Owner:MEDIPAL HLDG CORP
Method for lyophilization and device thereof
PendingUS20260175219A1Preparing sample for investigationLaboratory glasswaresEngineeringBiochemistry
Owner:ARGONAUT MFG SERVICES INC
Control system for a liquid filling level and microscope stage including such a system
A system for controlling a filling level of a reservoir filled with a liquid includes the reservoir configured to be filled with the liquid at least up to a maximum filling level. The system also includes a probe including a probe body, at least a section of the probe body extending, in a height dimension of the reservoir, from a first position to a second position, the first position being lower than the second position, and the second position being above the maximum filling level, and further including a temperature dependent sensor configured to generate a sensor signal based on a temperature at the second position, the temperature depending on the filling level. The system also includes a controller for controlling the filling level of the reservoir depending on the sensor signal such that the filling level is kept constant.
Owner:LEICA MIKROSYSTEME GMBH
Automated storage module
ActiveCN114814260BLighting and heating apparatusPreparing sample for investigationBarcodeProcess engineering
This invention provides a cryogenic storage system that enables automated storage and retrieval of samples in cryogenic environments, as well as automated transfer of individual samples between cryogenic environments. Stored samples are maintained below a cryogenic temperature threshold while remaining accessible. Samples can be organized and tracked by scanning their individual barcodes. Embodiments may also include multiple storage containers and provide transfer of individual samples between these containers and between the storage containers and a removable cryogenic storage device.
Owner:AZENTA US INC
In-vitro diagnostic reagent card incubation device
The invention discloses an in-vitro diagnostic reagent card incubation device, and belongs to the technical field of medical instruments, the in-vitro diagnostic reagent card incubation device comprises an incubation disc, a heating film is arranged on the top surface of the incubation disc, a heating film pressing plate is arranged on the top surface of the heating film, a plurality of incubation grooves used for inserting reagent cards are formed in the peripheral surface of the incubation disc, and the incubation disc is provided with an incubation cavity. A push block is arranged in the incubation groove, and a driving piece for driving the push block to move is arranged in the incubation groove. The device has the effect that a worker can conveniently take out the incubated reagent card.
Owner:BEIJING HUAYI JINGDIAN BIOTECHNOLOGY CO LTD
System and method for remotely monitoring cryogenic processing of sample
PendingCN121012824ALighting and heating apparatusPreparing sample for investigationEngineeringRemote sensing
A remote system for monitoring and controlling one or more devices for use in cryogenic processing of a sample is provided. A remote server (130) is provided that is capable of transmitting freezing curve data to one or more freezers (101,..., 10n), transmitting transport curve data to one or more transport devices, and transmitting thawing curve data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to freezing of the sample according to the freezing profile data, receiving detected data from the one or more transport devices relating to transport of the sample according to the transport profile data, and receiving detected data from the one or more thawing machines relating to thawing of the sample according to the thawing curve data.
Owner:BIOSAFE SA
Laboratory storage cabinet with a rotary element in a transfer air lock
Owner:HAMILTON STORAGE GMBH
Modular distributed cryogenic system
A modular distributed cryogenic distribution system, comprising: a common chamber housing cryogenic fluid conduits; and a plurality of cryochambers connected to the common chamber. A method of operating a modular distributed cryogenic distribution system comprising a common chamber housing cryogenic fluid conduits, and plural cryochambers connected to the common chamber, includes raising one the plurality of cryochambers room temperature while a second one of the plurality of cryochambers operates at a cryogenic temperature.
Owner:PSIQUANTUM CORP
Systems and methods for remotely monitoring the cryogenic processing of samples
A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample 100, 111, 112 ... 11n is provided. A remote server 50, 130 capable of transmitting freezing profile data to one or more freezers 10, 100, 101, 102 ... 10n, transmitting transportation profile data to one or more transportation devices 440, 500, and transmitting thawing profile data to one or more thawing devices. The remote server 50, 130 is also capable of receiving detected data from the one or more freezers 10, 100, 101, 102 ... 10n relating to the freezing of a sample 100, 111, 112 ... 11n in accordance with the freezing profile data, receiving detected data from the one or more transportation devices 440, 500 relating to the transportation of a sample 100, 111, 112 ... 11n in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample 100, 111, 112 ... 11n in accordance with the thawing profile data.
Owner:BIOSAFE SA
Automated depot module
PendingCN121201626ALighting and heating apparatusPreparing sample for investigationBarcodeProcess engineering
Cryogenic storage systems are provided that provide automated storage and retrieval of samples in cryogenic environments, as well as automated transfer of individual samples between cryogenic environments. The stored samples are maintained below a cryogenic temperature threshold while also being accessible. The samples can be neatened and tracked by scanning the barcodes of the samples. Embodiments may also include a plurality of storage reservoirs and provide for transfer of individual samples between the storage reservoirs and between the storage reservoir and the removable cryogenic storage device.
Owner:AZENTA US INC
Low-temperature vacuum plug rod with isolation cavity and core component rewarming method
The low-temperature vacuum inserting rod with an isolation cavity comprises an isolation cavity assembly and an inserting rod assembly; the isolation cavity assembly comprises a sealing assembly, a temperature recovery assembly, a suction flange and a vacuum valve, the sealing assembly is in sealing connection with the temperature recovery assembly, the temperature recovery assembly is in sealing connection with the vacuum valve, and the suction flange is connected with the temperature recovery assembly; the inserting rod assembly comprises a top end sealing plug, a feeder pipe and a bottom end sealing plug; the top end sealing plug and the bottom end sealing plug are respectively connected with two ends of the feeder pipe; the inserting rod assembly is located in the isolation cavity assembly and moves along the vertical direction of the isolation cavity assembly to an upper work position and a lower work position; when being in the upper work position and the lower work position, the top end sealing plug and the bottom end sealing plug respectively form a sealing structure with the sealing assembly. The application further discloses a core component temperature recovery method. The application has the advantages of not needing to be equipped with a heating temperature control loop, simplifying equipment, saving cost and fast temperature recovery.
Owner:UNIV OF SCI & TECH OF CHINA
Apparatus and method for producing microdroplets by freezing capillary
The application provides a device and a method for generating microdroplets by freezing a capillary tube, comprising a thermostat, a vertically placed glass capillary tube connected to the thermostat through a fixing device, and a liquid collecting box placed below the glass capillary tube. The fixing device comprises a base, a vertical guide rail and a capillary tube clamp connected in sequence, the liquid collecting box is placed on the base, and the capillary tube clamp clamps the glass capillary tube so that the glass capillary tube is located above the liquid collecting box. The application absorbs liquid into the glass capillary tube through capillary tension, vertically places the glass capillary tube above the liquid collecting device, gradually reduces the ambient temperature to-40 DEG C, and forms microdroplets under the action of the end gas-liquid interface tension due to the expansion of the liquid when the liquid is frozen and the extrusion bulging caused by the volume expansion of the liquid when the liquid is frozen. The liquid in the glass capillary tube starts to freeze and drops from the lower end to obtain microdroplets.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
Low-temperature valve box for superfluid helium low-temperature system and testing system and method of low-temperature valve box
PendingCN120194956ALighting and heating apparatusDomestic cooling apparatusMechanicsHelium cryogenics
The invention relates to the technical field of accelerators, and provides a low-temperature valve box for a superfluid helium low-temperature system and a testing system and method.The valve box comprises a strain measurement assembly, a low-temperature valve box body, a liquid helium storage tank, a supporting assembly, a helium cold shield pipeline and a superfluid helium preparation pipeline, and the two ends of the helium cold shield pipeline and the two ends of the superfluid helium preparation pipeline are both installed on the supporting assembly; the helium cold shield pipeline and the superfluid helium preparation pipeline are respectively provided with a low-temperature valve, a pressure sensor and a temperature sensor; an inlet of the liquid helium storage tank is communicated with the superfluid helium preparation pipeline, an outlet of the liquid helium storage tank is connected with a storage tank gas return pipeline, the storage tank gas return pipeline is provided with a pressure sensor and installed on the supporting assembly, and the liquid helium storage tank is provided with a liquid level meter; the strain measurement assembly is arranged on the supporting assembly, and the heat leakage load of the low-temperature valve box in the 2K-300K working temperature area and the mechanical load-temperature response characteristic of the supporting assembly can be obtained through a liquid level meter on the liquid helium storage tank, a temperature sensor on the pipeline and the strain measurement assembly on the supporting assembly.
Owner:INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI
Biochip for cryopreservation or thawing and resuscitation of biological tissue
Disclosed in the present invention is a biochip for cryopreservation or thawing and resuscitation of biological tissue, with four ends of the biochip being of a closed structure. The biochip includes: a section region, which is arranged in the middle and includes a plurality of sequentially arranged sections, with partition plates being provided between the sections, and the bottom of each section being provided with a fixing groove; and joint portions arranged on two sides of the section region. In the biochip having four ends being of a closed structure as provided in the present invention, a hydrogel or solution can be encapsulated in the plurality of sections of the biochip, such that the device is simple to operate and can effectively improve the efficiency of cryopreservation or thawing and resuscitation of embryos.
Owner:SHEN ZHEN BIOROCKS BIOTECHNOLOGY CO LTD
Vessels, devices, processes, and systems for tracking and managing items with circuitous custody chains
PendingEP4457029A4Air-pressure/air-lock chambersVaccination/ovulation diagnosticsEngineeringChain of custody
The approach disclosed herein can provide a closed-loop physical supply chain using a precision vessel. An example vessel includes an outer shell and an inner chamber that fits therein. The inner chamber includes a first compartment to removably house a product, and a second compartment with environmental control mechanisms. An enclosed layer, which may be secured to or integrated with the inner chamber, includes a controller and a communication interface to communicate with devices external to the precision vessel. Multiple sensors that monitor the first compartment send signals to the controller of the enclosed layer. A locking mechanism, when engaged, secures the outer shell to the inner chamber, and when disengaged, unlocks the outer shell from the inner chamber to thereby provide access to the first compartment and the product therein. The vessel can track its conditions and locations, and requires verification prior to disengaging the locking mechanism.
Owner:MEMORIAL SLOAN KETTERING CANCER CENT +2
Laboratory storage cabinet with a rotary element in a transfer air lock
ActiveUS12370537B2Lighting and heating apparatusDomestic cooling apparatusRotational axisExperimental laboratory
Owner:HAMILTON STORAGE GMBH
Low-temperature thermostat with large solid angle and optical system
PendingCN121446578ALighting and heating apparatusDomestic cooling apparatusOptic systemMechanical engineering
The invention discloses a low-temperature thermostat with a large solid angle and an optical system, the low-temperature thermostat can be used for trapping large-scale ions and atoms, an outer shell is provided with a first cavity and a second cavity which are communicated with each other, and at least part of the cavity wall of the second cavity is of a transparent structure; the first-stage shell is located in the outer shell and comprises a third cavity and a fourth cavity, the third cavity is located in the first cavity, at least part of the cavity wall of the fourth cavity is of a transparent structure, and the fourth cavity extends into the second cavity; the second-stage shell is located in the first-stage shell, the second-stage shell is provided with a sample cavity, the sample cavity extends into the fourth cavity, at least part of the cavity wall of the sample cavity is of a transparent structure, and the transparent area of the sample cavity, the transparent area of the fourth cavity and the transparent area of the second cavity are opposite. The outer shell, the first-stage shell and the sample cavity are transparent cavities which are arranged in a sleeved mode, so that the outer side of the outer shell has a large space for containing the ray machine equipment, the ray machine equipment does not need to be placed in the cryostat, the requirement of the ray machine equipment for low temperature resistance is lowered, and the cost of the ray machine equipment is reduced.
Owner:UNIV OF SCI & TECH OF CHINA +1
A gas meter air tightness testing device
ActiveCN120558482BDetection of fluid at leakage pointLighting and heating apparatusThermodynamicsGas meter
This invention discloses a gas meter airtightness testing device, specifically relating to the field of airtightness testing technology. It includes a test chamber, a standard gas meter, a gas meter under test, a pressurizing device, a valve assembly, and a pressure detection assembly. The valve assembly includes a pressure regulating valve, a venting valve, and a discharge valve. The gas outlet pipe of the standard gas meter is connected to the gas inlet pipe of the gas meter under test. The gas meter under test is placed in the test chamber. The venting valve is located on the connecting pipe of the gas outlet pipe of the gas meter under test. A leak detection assembly is also installed in the test chamber to detect whether there is gas leakage in the gas meter under test during the gradual cooling process of the test chamber. This invention can effectively simulate a low-temperature environment and test the airtightness of a diaphragm gas meter under low-temperature conditions. This allows for effective judgment of the actual quality of the diaphragm gas meter, providing more effective extreme characteristic testing data for diaphragm gas meters, which is beneficial for the continued research and design of diaphragm gas meters.
Owner:NINGBO JUFENG INSTR CO LTD
Biological safety protection system and method for deep hypothermia storage device
The invention discloses a biological safety protection system and method for deep hypothermia storage equipment, and relates to the technical field of deep hypothermia sample storage.The biological safety protection system comprises a cabin body and a first disinfection pipeline, the cabin body is used for containing the deep hypothermia storage equipment, and a sealing cabin door is arranged on the cabin body; a sample tube can be taken and placed from the deep hypothermia storage equipment by opening the sealing cabin door, and at least two first disinfection openings are further formed in the cabin body; the first disinfection pipeline is at least located in the cabin body, the end of the first disinfection pipeline is communicated with the first disinfection opening, an opening communicated with the interior of the cabin body is formed in the first disinfection pipeline, a first valve is arranged at the opening, and the outer side of the first disinfection opening is further sequentially communicated with a filter and an exhaust device; the filter is detachably arranged; the problem that the external environment is polluted by pathogens can be solved from multiple aspects, and the reliability is greatly improved.
Owner:BEIJING YIAN HUAMEI TECH CO LTD
Apparatus to facilitate transfer of biological specimens stored at cryogenic conditions
Owner:TMRW LIFE SCIENCES INC
Low-temperature storage system
ActiveUS12345462B2Lighting and heating apparatusAir-pressure/air-lock chambersInterior spaceMoisture penetration
An object of the present invention is to provide a low-temperature storage system that ensures minimal penetration of moisture into the low-temperature storage chamber from an external environment without involving an increase in size or complexity of the system configuration. The object is achieved by the configuration in this low-temperature storage system wherein a loading / unloading mechanism that carries storage objects into and out of the low-temperature storage chamber has an ancillary entry / exit preparation chamber. The entry / exit preparation chamber has a first anteroom with an interior space controlled to maintain a lower dew point than that of the external environment, and a second anteroom disposed between the first anteroom and the low-temperature storage chamber and having an interior space controlled to maintain a dew point that is between the dew point in the first anteroom and the dew point in the low-temperature storage chamber.
Owner:TSUBAKIMOTO CHAIN CO
Device for cooling a sample environment, sample holder and method for protecting a sample from vibration of a
PendingCN121420167APreparing sample for investigationCompression machinesHeat conductingRelative motion
Owner:REPRESENTATIVE INSTITUTION OF THE FREE STATE OF BAVARIA AT THE TECHNICAL UNIVERSITY OF MUNICH
Gas tightness detection device for gas meter
ActiveCN120558482ADetection of fluid at leakage pointLighting and heating apparatusGas meterGas leak
The invention discloses a gas meter airtightness detection device, and particularly relates to the technical field of airtightness detection, the gas meter airtightness detection device comprises a test box, a standard meter, a to-be-detected meter, a pressurization device, a valve assembly and a pressure detection assembly, the valve assembly comprises a pressure regulating valve, a deflation valve and a discharge valve, a gas outlet pipe of the standard meter is in butt joint with a gas inlet pipe of the to-be-detected meter, and the to-be-detected meter is arranged in the test box; the air release valve is arranged on a butt joint pipeline of an air outlet pipe of the to-be-tested meter, and an air leakage detection assembly is further arranged in the test box and used for detecting whether the to-be-tested meter leaks air or not in the process that the test box is gradually cooled. The low-temperature environment can be effectively simulated, the gas tightness of the diaphragm gas meter in the low-temperature environment can be tested, the actual quality of the diaphragm gas meter can be effectively judged, more effective limit characteristic detection data are provided for the diaphragm gas meter, and continuous research, development and design of the diaphragm gas meter are facilitated.
Owner:NINGBO JUFENG INSTR CO LTD
Control system for liquid filling level and microscope stage including such system
The inventive concept relates to a system (100) for controlling a filling level (X) of a liquid-filled reservoir (110), the system (100) comprising: a reservoir (110) configured to be filled with a liquid up to at least a maximum filling level (Xmax); a probe (120) including a probe body (122), at least a part of the probe body (122) extending in a height dimension of the reservoir (110) from a first position (126) to a second position (124), the first position (126) being lower than the second position (124), the second position (124) being higher than the maximum filling level (Xmax), and the probe (120) further including a temperature-dependent sensor (128) configured to generate a signal based on a temperature at the second position (124), the temperature depending on the filling level (X); and a controller (250) for controlling the filling level (X) of the reservoir (110) according to the sensor signal such that the filling level (X) remains constant.
Owner:LEICA MIKROSYSTEME GMBH