The invention discloses an unmanned ship launching and retrieving device. The device comprises a fixing frame, a guiding mechanism, rotating blocks and limiting blocks; the fixing frame comprises a fixing bracket and two identical lateral fixing parts which are both of a dual-layer structure; the open end of each lateral fixing part is provided with a guiding mechanism of a splay-shaped opening structure; the limiting blocks and the rotating blocks are fixedly to the outer side faces of upper and lower layer frames of the lateral fixing parts; when an unmanned ship is launched, the rotating blocks are rotated downwards, and the unmanned ship is pulled out smoothly; when the unmanned ship is retrieved, the unmanned ship is smoothly moved into the lateral fixing parts under the guidance of the guiding mechanism, the rotating blocks are rotated upwards, the upper and lower layer frames of the lateral fixing parts are connected, meanwhile, limiting is achieved, and the unmanned ship is prevented from rolling out. According to the unmanned ship launching and retrieving device, the unmanned ship can be safely and reliably launched and retrieved automatically under the complex sea environment, the unmanned ship can be prevented from rolling out in the lifting process, and the device has the advantages of being reliable in operation, simple in structure, high in autonomy and the like.