The invention discloses a hollow extrusion integrated plastic clamping plate, and a production process and equipment thereof. The hollow extrusion integrated plastic clamping plate comprises a lower supporting plate, supporting seats, support bars, upper support bars, straight slots, side slots, interval slots and hollowed-out slots. The production process of the hollow extrusion integrated plastic clamping plate comprises the following technological steps of feeding, extrusion, hollow forming, slot forming, cooling setting and cutting. The production equipment of the hollow extrusion integrated plastic clamping plate comprises an extruder, a mold, a die cutting machine, a cooling setting machine, a first conveyor belt, a cutter and a second conveyor belt. The hollow extrusion integrated plastic clamping plate can flexibly adapt to the hollow rato according to the bearing requirements, and materials are saved. Various types of different materials can be adopted to be mixed for molding.The hollow extrusion integrated plastic clamping plate is flexible in use and high in universality. The equipment and the mold are low in cost, flexible in manufacturing, applicable to products on different occasions and high in production efficiency.