37results about How to "Reduce chronic pain" patented technology

Systems, devices and methods for applying therapeutic transcranial magnetic stimulation (TMS) to at least one superficial cortical target brain region and at least one deep brain target so that the induced current points between the superficial cortical and deep brain targets. Systems may include two TMS electromagnets configured for treating a patient by stimulating at least one deep brain region with one TMS magnet at the same time that a second TMS magnet stimulates at least one superficial cortical brain region. Also described are positioners to secure at least two TMS magnets in a substantially fixed arrangement relative to the patient's head, while allowing for fine adjustment of position and orientation of each of the TMS magnets individually to conform them to the shape of the contact surface of the body and to direct the vector direction of the overall induced current from the magnets.

A method and apparatus for reducing chronic pain in animals by radio frequency (RF) neuromodulation of peripheral nerves of the animal is disclosed. The method, using the disclosed apparatus, comprises the steps of attaching active and dispersive percutaneous probes at respective active and dispersive locations relative to a peripheral nerve of the patient associated with the pain to be reduced; generating a first pulsed RF signal for coupling to the active and dispersive probes to verify the location of the peripheral nerve; and generating a second pulsed RF signal for coupling to the active and dispersive probes to modify propagation of pain sensation in the peripheral nerve without ablation thereof. In one embodiment of the apparatus, the active percutaneous probe includes an RF cannula having a conductive spatulate blade conformably attached to a dorsal side of a curved, blunt-ended tubular tip portion of the RF cannula. In another embodiment of the apparatus, a dispersive percutaneous probe includes a pair of 22 gauge needles connected to ground return conductors. In yet another embodiment of the apparatus, a pulsed RF generator is modified to provide specific outputs adapted to the neuromodulation of peripheral nerves in veterinary patients.

The invention discloses a multifunctional rehabilitation auxiliary therapeutic instrument for nurses in the neurology department, and belongs to the technical field of medical equipment application. Abed body is divided into a left bed board and a right bed board which are mutually hinged, the left bed board can driven by an oil cylinder to adjust the angle through rising and falling relative tothe right bed board, in the massage process, the nurses do not need to take efforts to carry a patient, and the patient can adopt multiple body positions to use the multifunctional rehabilitation auxiliary therapeutic instrument; meanwhile, a head massage instrument integrated on the multifunctional rehabilitation auxiliary therapeutic instrument is used for massaging the scalp of the patient, a neck massage instrument is used for massaging neck muscles of the patient, waist massage balls are used for massaging waist muscles, thigh massaging rollers are used for massaging muscles of hips and thigh roots of the patient, shank massage instruments are used for massaging muscles such as calves of the patient, and foot massage instruments are used for massaging acupuncture points of soles of the patient; the same rehabilitation auxiliary therapeutic instrument can massage multiple muscles and acupuncture points of the patient.

The present invention provides methods of treating fibromyalgia or other diseases or conditions causing widespread pain and / or fatigue. In particular, the invention provides pharmaceutical compositions comprising droxidopa alone, or in combination with one or more further active agents, that can be used in the inventive methods. The methods of treatment can comprise treating, preventing, reducing, or eliminating a variety of symptoms recognized as indicative of fibromyalgia, such as chronic pain, allodynia, hyperalgesia, fatigue, sleep disturbance, and depression.

A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

The present invention provides methods of treating fibromyalgia or other diseases or conditions causing widespread pain and / or fatigue. In particular, the invention provides pharmaceutical compositions comprising droxidopa alone, or in combination with one or more further active agents, that can be used in the inventive methods. The methods of treatment can comprise treating, preventing, reducing, or eliminating a variety of symptoms recognized as indicative of fibromyalgia, such as chronic pain, allodynia, hyperalgesia, fatigue, sleep disturbance, and depression.

Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and / or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and / or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and / or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and / or sedatory activity.

A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

A system and method for generating an electrical signal for use in biomedical applications may have power efficient features, support battery powered operation and, support a reduced risk of shock hazard. The system may include a controller for generating one or more control signals operable to control pulse generating and waveform processing circuits. The control signals may include at least two states alternating in a chosen pattern as a function of time. During at least one of the control signal states, an oscillator for generating a pulsed signal may be operable. During at least another of the control signal states, the oscillator can be disabled and completely shut off in order to conserve considerable power. The generated pulses may be processed to provide desired intensity and frequency components. The processed signals may be applied to biological material.

The invention provides a compact type cervical vertebra massager. The compact type cervical vertebra massager comprises a massaging main body, and a left neck pillow and a right neck pillow which areconnected with two ends of the massaging main body, wherein the massaging main body comprises a shell, an airbag, buffering sponge, covering mesh cloth, a left massaging part and a right massaging part; a mounting bracket is arranged at the inner side of the shell; the airbag is mounted on the mounting bracket; the buffering sponge is arranged at the inner side of the airbag; the covering mesh cloth is arranged at the inner side of the buffering sponge; the covering mesh cloth covers the buffering sponge; the edge of the airbag is connected with the shell; the left massaging part and the rightmassaging part are mounted at the left and right sides of the covering mesh cloth respectively. According to the compact type cervical vertebra massager, a first limiting part and a second limiting part are arranged and can be used for resisting part of pressure formed by the expansion of the airbag and a condition that the pressure of the airbag to a neck is too great is avoided; pulses are generated by a first pulse massaging assembly and a second pulse massaging assembly and are used for carrying out pulse therapy on the neck; vibration generated by a first vibrator and a second vibrator is conducted to an acupuncture point and partial tissues to generate a certain stimulation effect.

The invention discloses a control system of a pneumatic massage instrument, which is applied to the pneumatic massage instrument and belongs to the technical field of massage. The pneumatic massage instrument comprises an air bag array formed by a plurality of air bags, a valve group and an air pressure source; the air pressure source is connected with the air bag array through the valve group, and the valves correspond to the air bags one to one. The control system comprises an instruction input unit, through which a user inputs a control instruction; a control unit, connected with the instruction input unit; and a valve unit, connected with the control unit and used for switching the working state of each valve according to a control signal. The control system has the beneficial effectsas follows: the air bag array is adopted to massage a human body, the massage strength to the human body is adjusted by adjusting the air pressure of the air bags, human joints or other soft tissues are not prone to being damaged, and the number of the air bags can be increased or decreased and the arrangement mode of the air bag array can be changed according to the size curve of the human body by modifying a program in the instruction input unit, so that the pneumatic massage instrument can fit the curve of the human body, and achieve partial or whole-body massage.

The invention provides a waist massager. The waist massager comprises a first shell, a second shell, at least one massage head, a PCB, a remote controller and a lithium battery, wherein the first shell is connected with the second shell, containing space is enclosed between the first shell and the second shell, and the second shell is provided with at least one first mounting hole; the massage heads correspond to the first mounting holes one to one, each massage head comprises an elastic telescopic cover, a vibration massage assembly and an expansion massage assembly, each vibration massage assembly is cooperatively arranged in the corresponding first mounting hole through the corresponding elastic telescopic cover, and the expansion massage assemblies are arranged on the second shell to drive the vibration massage assemblies to perform reciprocating telescopic movement; the remote controller is in signal connection with the PCB; the lithium battery is arranged in the containing spaceand is connected with the PCB. The massage heads integrate various massage functions such as vibration, heat energy and electronic pulse energy, and the massage heads adopt hanging type retractable design, so the energy can be concentrated to a point for release, thereby achieving excellent massage experience.

Equipment for self-care of patients with chronic pain, through inducing, intensifying and maintaining their own frissons and where multisensory and multimodal stimuli are used to achieve it; musical, visual, aromatic and vibrotactile and cold are applied on the cutaneous surface of the spine. In addition, the method for using them through perceptual learning is presented. The equipment consists of a computer and a computer system with a music and video player, lighting, presentation of aromas and a closed hydraulic circuit with a hydraulic actuator.

The present invention discloses a massage instrument with head and eye massage and visual function training functions. The massage instrument is used for assisting or replacing human beings to performwork of head and eye massage, visual function detection and visual function training. The massage instrument comprises a massage helmet and a visual function training insert card box, the visual function training insert card box is detachably connected with positions, corresponding to eyes of human body, of the massage helmet; and massage columns for accurate massage are all arranged on inner sides of the massage helmet and the visual function training insert card box corresponding to human body massage acupuncture points. The massage instrument can massage the corresponding acupuncture points of the head and the eyes through the massage columns simulating acupuncture point massage of human hands, can also relax muscles, relieve nerves, promote blood circulation, strengthen cell metabolism, enhance skin elasticity, relieve fatigue, relieve various chronic pains, acute pains and muscle soreness and relieve pressure, meanwhile, conducts corresponding visual function training on the eyesof the human body through various visual function training contents in the visual function training insert card box, and intelligently analyzes conditions and collects data.

This invention provides methods utilizing ketamine for the treatment of motor disorders and / or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.

A therapeutic bracelet, including a bracelet body having one or more cavities formed therein; a catalyst solution contained within each of the one or more cavities; an electrical connector electrically attached or coupled to the bracelet body; a connecting cord electrically attached or coupled to the electrical connector; and a plug assembly, wherein the plug assembly includes a “live” pin or blade, a neutral pin or blade, and an earth / ground pin or blade, wherein the “live” pin or blade and the neutral pin or blade are electrically disconnected from the connecting cord and the earth / ground pin or blade, and wherein the earth / ground pin or blade is electrically connected to the connecting cord.

A cannabis-based therapeutic product for treatment of chronic pain produced by separating hash resin from plant material of the cannabis plant, pressing the hash resin to expel oil, leaving spent hash resin, extracting further cannabinoids from the spent hash resin using MCT oil, separating the cannabis compounds from the oils using high pressure liquid chromatography, flash chromatography, or similar techniques, and processing selected cannabis compound formulations into a form suitable for administration as a therapeutic product for treatment of chronic pain. The therapeutic product has at least 28% w / w cannabinol (CBD), and at least 2% w / w β-myrcene.

The invention discloses an examination device for a nurse, and belongs to the technical field of medical apparatus and instruments. For the examination device, a body massage device, an oral cavity protector and a pin type examination instrument are integrated on a diagnosis hammer body, when not in use, the body massage device, the oral cavity protector and the pin type examination instrument canbe stored in a first mounting groove, a second mounting groove and a third mounting groove, thus the occupied space is small, and the carrying of the nurse is convenient; the nurse can use the body massage device to massage the muscle of a patient according to demands, with the oral cavity protector integrated on the diagnosis hammer body, the accident of tongue bite injury occurring during whole-body spasm of an epileptic can be prevented, with the pin type examination instrument, tactile sense examination is carried out on patients of the neurology department who are slow in reacting or lose consciousness, various examination instruments are integrated into a whole within the limited space, so that the nurse can conveniently select different examination instruments for carrying out primary diagnosis according to the disease conditions of the patients during clinical reception, therefore, the problem that the existing medical examination instruments are single in function is solved,and the efficiency of the nurse in assisting a doctor in performing diagnosis on the patients is greatly improved.

The invention discloses a glass type rhinitis preventing nose bridge massage vibrator. The glass type rhinitis preventing nose bridge massage vibrator comprises a glass frame and Bluetooth headsets, wherein the Bluetooth headsets are arranged at the bottoms of the legs of the glass frame and provided with chargeable batteries; both sides of the nose frame of the glass frame are provided with electric micro vibrators; one of the legs of the glass frame is provided with a charging interface, and the other leg of the glass frame is provided with a vibrator switch; the electric micro vibrators are powered through the chargeable batteries of the Bluetooth headsets; the inside of the nose frame of the glass frame under the electric micro vibrators is provided with a bamboo charcoal mesh band with an opening at the top. The glass type rhinitis preventing nose bridge massage vibrator vibrates acupoints of nose through physical vibration to promote blood circulation, to achieve massage and relief effects, to facilitate nose muscle massage and relief, to relieve chronic pain, acute pain of nose as well as muscular soreness, to enhance activity of nose and reduce the possibility of rhinitis.

The present disclosure teaches systems and methods of diagnosing and treating the distinct biologic components that contribute to chronic pain symptoms experienced by patients. A biologic sample is obtained from a patient. Levels of two or more biomarkers (e.g., methylmalonic acid, homocysteine, xanthurenic acid, 3-hydroxypropyl mercapturic acid (3-HPMA), pyroglutamate, hydroxymethylglutarate (HMG), quinolinic acid, kynurenine acid, 5-hydroxyindoleacetate (5-HIAA), vanilmandelate (VMA), and ethylmalonic acid) in the biologic sample are experimentally determined. Based on the existence of abnormal results in one or more biomarkers the patient is diagnosed as having the nerve health, oxidative stress, chronic inflammation pain, and / or neurotransmitter pain components to their chronic pain. Based on the resulting diagnoses administration of certain support compounds is directed. The patient may retest after a sufficient period of time to observe any longitudinal differences in the test results and adjust treatment accordingly. Further, the biomarker data gathered from pain-neutral and chronic pain patients (particularly those using opioid therapies) will be used to characterize biochemistries going forward.

The invention provides a soft medical massage nursing device for the abdomen. The soft medical massage nursing device comprises an installation shell, an upper telescopic piece, a middle telescopic piece, a lower telescopic piece, an upper massage assembly, a middle hot compress assembly, a lower massage assembly, a PCB and a battery. An upper sliding block is installed in the upper cavity in a sliding mode, the upper massage assembly is installed on the upper sliding block and extends out of the upper opening, and the upper telescopic piece is connected with the upper sliding block and drivesthe upper sliding block to move back and forth in the upper cavity through telescoping; a fixed plate is mounted in the middle chamber, and the middle telescopic piece is mounted on the fixed plate;a lower sliding block is slidably installed in the lower cavity, the lower massage assembly is installed on the lower sliding block and extends out of the lower opening, and the lower telescopic pieceis connected with the lower sliding block and drives the lower sliding block to move back and forth in the lower cavity; the PCB and the battery are both mounted in the mounting shell. The upper sliding block drives the upper massage assembly to move back and forth to gently massage the abdomen back and forth, the middle hot compress assembly performs hot compress treatment on the abdomen, and the lower sliding block drives the lower massage assembly to move back and forth to gently massage the abdomen back and forth.

Methods of reducing neuronal sensitivity, thereby reducing inflammation and chronic pain, are disclosed herein. Particularly disclosed are methods of administrating the apurinic / apyrimidinic endonuclease 1 redox factor 1 (APE1 / Ref-1) inhibitor, APX3330, to enhance the DNA base excision repair (BER) pathway, thereby reducing neuronal sensitivity to inflammatory mediators and alleviating inflammatory or chronic pain.

A method of treating a patient exhibiting abdominal or pelvic pain by applying shockwaves or acoustic pulses to the lower spine, lumbar and sacral spine, to modulate, reduce or relieve spinal stenosis, inflammation, injury or disease and has the steps of: activating an acoustic shock wave or acoustic wave generator or source to emit acoustic shock waves or pulses from a fixed acoustic wave source or a handheld shock wave head or from electrodes embedded within a catheter with or without a fluid filled balloon catheter; and administering a plurality of acoustic shock or acoustic waves in a pulse or wave pattern within the targeted tissue of less than 10.0 mJ / mm2 per shock wave, the plurality of acoustic shock or acoustic waves in a pulse or wave pattern should be directed to a portion of a lower spine exhibiting chronic pain and / or inflammation.

The invention discloses lipids and lipids compound used as medicines for treating pain and an application method of the lipids and the lipids compound. The lipids and lipids compound comprise the following lipids compositions including eicosapentaenoic acid ethyl ester (EE-EPA), docosapentaenoic acid ethyl ester (EE-DPA), docosahexaenoic acid ethyl ester (EE-DHA), ethyl linoleate (EE-LA), arachidonic acid ethyl ester (EE-AA), 12-hydroxy eicosanoic acid ethyl ester (EE-12-HETE), linoleic acid (LA), docosahexaenoic acid (DHA), arachidonic acid (AA), eicosapentaenoic acid (DPA) and 12-hydroxy eicosanoic acid (12-HETE), wherein the DPA is all-cis type-7,10,13,16,19-docosapentaenoic acid (DPA) and the like as well as combined application of a variety of lipids; medicines are administered in anoptimal dosage amount in intrathecal, epidural or intranasal ways while combined application of the medicines is allowed, and the medicines can be allowed to repeatedly and continuously administered through the ways, and the medicines directly act upon a central nervous system, so that potential side effects of the medicines and side effects of opiates medicines are reduced as much as possible when the pain is suppressed or prevented by adopting the medicines at the same time.

The invention discloses a massager with the functions of head-eye massage and visual function training, which is used to assist or replace human beings to perform head-eye massage, visual function detection and visual function training. Including: massage helmet, visual function training insert box, detachable connection between visual function training insert box and massage helmet corresponding to human eye position; massage helmet and visual function training insert box are equipped with precise massage points corresponding to human body massage points massage column. The massager can not only massage the corresponding acupoints on the head and eyes through the massage column that simulates the acupoint massage of human hands, but also relax muscles, soothe nerves, promote blood circulation, strengthen cell metabolism, enhance skin elasticity, relieve fatigue and alleviate various diseases. Chronic pain, acute pain and muscle soreness can reduce stress; at the same time, through the various visual function training content in the visual function training insert box, the corresponding visual function training can be carried out on the human eye, and the situation can be intelligently analyzed and collected data.