The invention belongs to the technical field of
biomedicine, and particularly relates to a method for evaluating the elastic
contraction function of
lung tissue and application thereof.The method for evaluating the elastic
contraction function of the
lung tissue comprises the following steps that (1) a semi-
automatic segmentation module of ITK-SNAP
software is adopted for
lung area recognition, and an initial
lung segmentation mask is generated; performing 10
voxel morphological expansion on the
mask to generate an inspiration sequence
mask and an expiration sequence mask; (2) outputting to obtain a
shape transformation matrix; the method comprises the following steps: quantitatively analyzing lung elastic contraction characteristics of an IPF patient by using an elastic registration
algorithm, and analyzing the correlation between elastic contraction parameters and
lung function parameters, dyspnea degree, exercise tolerance, health-related life indexes and the correlation between
pulmonary fibrosis degree and
pulmonary blood vessel related parameters quantified based on HRCT (
High Resolution Computed Tomography); mRI-based lung elastic contraction quantitative analysis is expected to become a novel image marker and is used for noninvasive evaluation of
lung tissue elasticity of an IPF patient.