The invention discloses an informatization application cluster platform of small and medium enterprises. The informatization application cluster platform comprises a portal management system, an enterprise logistics supply chain resource planning management system, an enterprise resource planning management system, an enterprise distribution resource planning and supply chain management system, an enterprise customer relation management system, an enterprise collaborative working platform management system, an enterprise product data management and product life cycle management system, an enterprise human resource management system, an enterprise operating management talent assessment system, an enterprise educational training network platform integrated system and a decision supporting analysis system. The informatization application cluster platform of the small and medium enterprises has the advantages that: by real-time on-line application and management for a plurality of small and medium enterprises, the safety of the operation data of on-line enterprises can be guaranteed; the investment of economic and technical talents for the informatization application of the small and medium enterprises of China is greatly reduced; an enterprise management bottleneck is optimized; the information technology (IT) application cost of the enterprises is greatly saved; and the implementation of the informatization of the small and medium enterprises is simplified.