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35 results about "Ultra low field" patented technology

Ultra-low field nuclear magnetic resonance and magnetic resonance imaging to discriminate and identify materials

An ultra-low magnetic field NMR system can non-invasively examine containers. Database matching techniques can then identify hazardous materials within the containers. Ultra-low field NMR systems are ideal for this purpose because they do not require large powerful magnets and because they can examine materials enclosed in conductive shells such as lead shells. The NMR examination technique can be combined with ultra-low field NMR imaging, where an NMR image is obtained and analyzed to identify target volumes. Spatial sensitivity encoding can also be used to identify target volumes. After the target volumes are identified the NMR measurement technique can be used to identify their contents.
Owner:TRIAD NAT SECURITY LLC

Biomagnetic resonance device and measuring method therefor

Provided are an ultra-low-field nuclear magnetic resonance device and an ultra-low-field nuclear magnetic resonance measuring method. The method includes applying a first measurement bias magnetic field corresponding to an excitation frequency of a coherent biomagnetic field generated in association with the electrophysiological activity of human body organs, applying a second measurement bias magnetic field having the same direction as the first measurement bias magnetic field and having a different magnitude than the first measurement bias magnetic field, and measuring a magnetic resonance signal generated in the human body by using magnetic field measuring means.
Owner:KOREA RES INST OF STANDARDS & SCI

Direct Imaging of Neural Currents Using Ultra-Low Field Magnetic Resonance Techniques

Using resonant interactions to directly and tomographically image neural activity in the human brain using magnetic resonance imaging (MRI) techniques at ultra-low field (ULF), the present inventors have established an approach that is sensitive to magnetic field distributions local to the spin population in cortex at the Larmor frequency of the measurement field. Because the Larmor frequency can be readily manipulated (through varying Bm), one can also envision using ULF-DNI to image the frequency distribution of the local fields in cortex. Such information, taken together with simultaneous acquisition of MEG and ULF-NMR signals, enables non-invasive exploration of the correlation between local fields induced by neural activity in cortex and more ‘distant’ measures of brain activity such as MEG and EEG.
Owner:TRIAD NAT SECURITY LLC +1

Ultra-low field nuclear magnetic resonance method to discriminate and identify materials

An ultra-low field (ULF) nuclear magnetic resonance (NMR) and / or magnetic resonance imaging (MRI) system can be used for rapid identification and discrimination of materials, e.g., liquid in opaque containers and / or materials in or on human bodies. The system utilizes the ability of ULF NMR / MRI to measure NMR parameters in magnetic fields that can be easily changed in field strength and orientation.
Owner:LOS ALAMOS NATIONAL SECURITY

Ultra-low field nuclear magnetic resonance and magnetic resonance imaging to discriminate and identify materials

Method comprising obtaining an NMR measurement from a sample wherein an ultra-low field NMR system probes the sample and produces the NMR measurement and wherein a sampling temperature, prepolarizing field, and measurement field are known; detecting the NMR measurement by means of inductive coils; analyzing the NMR measurement to obtain at least one measurement feature wherein the measurement feature comprises T1, T2, T1ρ, or the frequency dependence thereof; and, searching for the at least one measurement feature within a database comprising NMR reference data for at least one material to determine if the sample comprises a material of interest.
Owner:TRIAD NAT SECURITY LLC

System and method for magnetic current density imaging at ultra low magnetic fields

Preferred systems can include an electrical impedance tomography apparatus electrically connectable to an object; an ultra low field magnetic resonance imaging apparatus including a plurality of field directions and disposable about the object; a controller connected to the ultra low field magnetic resonance imaging apparatus and configured to implement a sequencing of one or more ultra low magnetic fields substantially along one or more of the plurality of field directions; and a display connected to the controller, and wherein the controller is further configured to reconstruct a displayable image of an electrical current density in the object. Preferred methods, apparatuses, and computer program products are also disclosed.
Owner:TRIAD NAT SECURITY LLC

Ultra-low field magnetic imaging device for living small animals

The invention relates to an ultra-low field magnetic imaging device for living small animals, which belongs to the technical field of magnetic imaging, and solves the problems that an ultra-low fieldmagnetic imaging device in the prior art is complex in structure and is not suitable for large-size small animal living body scanning. The ultra-low field magnetic imaging device comprises a pushing unit and a magnetometer unit, wherein the pushing unit comprises a scanning displacement table, a push rod and an objective table; the scanning displacement table, the push rod and the objective tableare connected in sequence; the magnetometer unit comprises a magnetic shield, a scanning channel, an optical channel, an atomic gas pool, a laser source and a detector, the scanning channel penetratesthrough the side face of the magnetic shield, the atomic gas pool is arranged on one side of the scanning channel, and the laser source and a detector are arranged outside the magnetic shield and located at one end of the optical channel. The ultra-low field magnetic imaging device is simple in structure, convenient to assemble and disassemble, and suitable for large-size small animal living bodyscanning on the premise that the ultra-low field detection sensitivity is guaranteed.
Owner:INST OF CHEM CHINESE ACAD OF SCI +1

Space magnetic field and full-tensor gradient measurement system and method based on spatial correlation

The invention relates to a space magnetic field and full-tensor gradient measurement system and method based on spatial correlation. The measurement system is characterized by comprising a first flux-gate magnetometer, a second flux-gate magnetometer, an electric driver and a digital acquisition system, a certain distance is reserved between the first flux-gate magnetometer and the second flux-gate magnetometer, and directions of three axes are parallel to one another; the first flux-gate magnetometer keeps stationery in the measuring process to serve as a reference; the second flux-gate magnetometer is fixed at the movable end of the electric driver and can reciprocate parallelly; each flux-gate magnetometer outputs by three axes. The system is easy to set up, low in cost, simple to process and capable of obtaining accurate space magnetic field distribution; meanwhile, close-range arrangement of the flux-gate magnetometers is avoided, mutual interference of the flux-gate magnetometers can be eliminated to the utmost degree, and the method has good application prospects in applications of ultra-low field nuclear magnetic resonance and imaging thereof, biomagnetic research, magnetic geophysical exploration and the like.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Ultra-low field magnetic resonance imaging system

The invention relates to an ultra-low field magnetic resonance imaging system, characterized in that the system comprises a non-magnetic moving cabinet body with rolling casters at the lower part, a radio frequency shielding device is arranged above the non-magnetic moving cabinet body, and the radio frequency shielding device comprises a frame-shaped magnetic conductive rack having a cross section in the shape of a square, upper and lower magnets symmetrically located on the upper and lower sides inside the frame-type magnetic inductive rack, an upper gradient coil and a lower gradient coil,and a transmitting coil and a receiving coil located between the upper gradient coil and the lower gradient coil; and also included are a front shield cover, a rear shield cover, and an openable shield cover, a drawing type bed plate is arranged above an inner shield cover, and the drawing type bed plate can be completely placed in a patient detection room. Compared with the prior art, the invention has the advantages that the whole magnetic resonance system is reduced onto the non-magnetic moving cabinet body, the whole radio frequency shielding device is compact in structure, with no need tobuild a large shielding room, and the system is suitable for early stage diagnosis of acute and super acute cerebral hemorrhage.
Owner:宁波穿山甲机电有限公司

Imaging device of handheld ultra-low-field MRI (magnetic resonance imaging) system

The utility model relates to an imaging device of a handheld ultra-low-field MRI (magnetic resonance imaging) system, which comprises a hardware part and a software part. The hardware part comprises an intelligent handheld device, a polarizing coil module, a gradient coil module, a receiving coil module and a magnetic flux probe, the software part is arranged on the intelligent handheld device and comprises a probe shell; the polarizing coil module, the gradient coil module, the receiving coil module and the magnetic flux probe are all arranged in the probe shell; and the software part also comprises a magnetic field parameter transformation module and an image reconstruction module. The magnetic field parameter transformation module transforms irregular magnetic field parameters detected by the magnetic flux probe into magnetic field parameters suitable for the existing magnetic resonance imaging algorithm, and images can be reconstructed by adopting the existing magnetic resonance imaging algorithm. Therefore, the polarizing coil module, the gradient coil module, the receiving coil module and the magnetic flux probe are arranged on the same side of an object to be tested, and the MRI system can be handheld, can substitute the 0.1-1T permanent magnet MRI equipment, and is suitable for small and medium hospitals.
Owner:SHANTOU DONGFANG ULTRASONIC TECH

Power-frequency noise suppression device based on SQUID triaxial magnetometer

The invention provides a power-frequency noise suppression device based on an SQUID triaxial magnetometer. The power-frequency noise suppression device is applied to an ultra-low-field nuclear magnetic resonance system and comprises a Dewar, an SQUID second-order gradient meter, the SQUID triaxial magnetometer and a reading circuit. The SQUID second-order gradient meter and the SQUID triaxial magnetometer are both arranged in the Dewar. The SQUID second-order gradient meter is used for detecting a nuclear magnetic resonance signal in the ultra-low-field nuclear magnetic resonance system. The SQUID triaxial magnetometer includes three SQUID magnetometer bodies orthometric mutually and is used for detecting power-frequency noise in a detecting environment magnetic field. The reading circuit is used for reading output voltages of the SQUID second-order gradient meter and the SQUID triaxial magnetometer and obtaining the nuclear magnetic resonance signal undergoing power-frequency noise suppression through processing. The power-frequency noise suppression device based on the SQUID triaxial magnetometer effectively inhibits power-frequency noise interference and improves the signal-to-noise ratio of the nuclear magnetic resonance signal.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Metal implant magnetic resonance imaging method and system, terminal and storage medium

The invention discloses a metal implant magnetic resonance imaging method and system, a terminal and a storage medium. The method is applied to an ultra-low field magnetic resonance imaging device, and is characterized by comprising the following steps: acquiring safety scanning parameters according to the information of a metal implant; setting radio frequency parameters and imaging parameters of the ultra-low field magnetic resonance imaging device according to the safety scanning information; and carrying out magnetic resonance imaging according to the radio frequency parameters and the imaging parameters. The magnetic resonance imaging device with an ultra-low field can be applied to magnetic resonance imaging of the metal implant, and the obtained image is clear and cannot be affected by the high inherent magnetic susceptibility of the metal implant.
Owner:成都易检医疗科技有限公司

Ultra-low-field nuclear magnetic resonance imaging device applied to cerebral stroke diagnosis

The present invention belongs to the field of magnetic resonance imaging devices, and relates to an ultra-low-field nuclear magnetic resonance imaging device applied to cerebral stroke diagnosis. Thedevice comprises a magnet system and a support structure, the magnet system is configured to generate a spherical target region, the target region is located at the geometric center of the magnet system, the support structure is arranged at the outer portion of the magnet system for supporting the magnet system; and the magnet system comprises a main magnet and a gradient coil. The ultra-low-fieldnuclear magnetic resonance imaging device can perform image monitoring for a brain for a long time, is convenient to move, light in weight, small in volume and compact in structure, can meet the clinic demands and can be applied to auxiliary clinical diagnosis.
Owner:CHONGQING UNIV IND TECH RES INST

Ultra-low-field nuclear-magnetic-resonance direct myocardial electrical activity detection method and ultra-low-field nuclear-magnetic-resonance device

Provided are ultra-low-field nuclear-magnetic-resonance myocardial electrical activity detection method and an ultra-low-field nuclear-magnetic-resonance device. The ultra-low-field nuclear-magnetic-resonance device includes magnetic shielding means; high-sensitivity magnetic field measuring means disposed adjacent to a measurement target disposed inside the magnetic shielding means; and bias magnetic field generating means for providing an external measurement bias magnetic field, corresponding to a proton magnetic resonance frequency (nuclear magnetic resonance frequency) corresponding to a frequency of periodic myocardial activity of a lesion desired to be measured, to the measurement target. The high-sensitivity magnetic field measuring means measures a magnetic resonance signal generated from the measurement target.
Owner:KOREA RES INST OF STANDARDS & SCI

Miniature ultra-low field nuclear magnetic resonance spectrometer

The invention discloses a small ultra-low field nuclear magnetic resonance spectrometer, which comprises a sample flowing module for driving a liquid sample to flow between a polarization region and a detection region; the hyperpolarization module is used for polarizing the liquid sample; the probe and sample fixing module is used for fixing the detection area sample tube and the nuclear magnetic detection module; the pulse applying module is used for applying a pulse to the liquid sample, transferring a nuclear magnetization vector of the sample to a transverse direction, and carrying out free evolution of sample spinning; the nuclear magnetic detection module is used for detecting a free evolution spinning signal of the liquid sample and converting the free evolution spinning signal into a voltage signal; the magnetic shielding module shields a geomagnetic field to ensure an ultra-low field environment; and the time sequence control module is used for controlling each module to work and collecting voltage signals. Through the combination of the modules, the detection process is carried out in a magnetic shielding environment, the dependence of a traditional nuclear magnetic resonance spectrometer on a strong magnetic field is eliminated, and the system complexity and the manufacturing cost are effectively reduced; the device is simple in overall structure, small in size, convenient to move and capable of adapting to nuclear magnetic detection in various environments.
Owner:UNIV OF SCI & TECH OF CHINA

Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI)

The invention relates to a superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI). The SQUID cooling device comprises a cooling head and a cooling conduit, wherein the cooling head is connected with an external cooling device through the cooling conduit. Ultra low temperature suitable for the operation of an SQUID is acquired through a cold supply device and transmitted to the SQUID through the cooling conduit and the cooling head so as to provide an ultra low temperature working environment for the SQUID; because only the cooling head and partial cooling conduit need to be encapsulated, liquid helium and liquid nitrogen are not needed; because only the cooling head and the cooling conduit need to be encapsulated, the cooling device has simple and practical structure, and saves the operation and maintenance costs; and the device is suitable to be used as the cooling device for the SQUID of the handheld ultra low field MRI. A cooling capsule is arranged, and one of the cooling capsule and an external refrigerating device can be selectively used; under the condition that the external refrigerating device is started, the used cooling capsule can be inserted into the installation cavity of the cooling capsule; and through the external refrigerating device, the coolant in the cooling capsule is newly liquefied, so that the cooling capsule can be recycled.
Owner:SHANTOU DONGFANG ULTRASONIC TECH

Multi-mode FePt-coated Fe3O4 nano contrast agent as well as preparation method and application thereof

ActiveCN114344489AObvious residual magnetic signalEnabling Multimodal ImagingMaterial nanotechnologyNanomedicineT2 contrastPolyethylene glycol
The invention discloses a multi-mode FePt-coated Fe3O4 nano contrast agent as well as a preparation method and an application of the multi-mode FePt-coated Fe3O4 nano contrast agent. The multi-mode FePt-coated Fe3O4 nano contrast agent disclosed by the invention is a FePt-coated Fe3O4 inorganic nano particle of which the surface is modified with polyethylene glycol; the FePt-coated Fe3O4 inorganic nanoparticles are nanocrystals with FePt alloy as a core and Fe3O4 as a shell, the overall size of the FePt-coated Fe3O4 inorganic nanoparticles is 5-20 nm but not 20 nm, and the size of a core region is 1-10 nm. The FePt-coated Fe3O4 nano contrast agent provided by the invention can provide a positive T1-T2 contrast ratio in an MRI (Magnetic Resonance Imaging) strong magnetic field, provides an obvious residual magnetism signal in ultra-low field magnetic imaging, realizes brand new T1-T2-ULF (Ultra-low Frequency) multi-modal imaging, can be applied to the fields of medical imaging, targeted therapy, visual tracking and the like, and has remarkable practical significance and practical value.
Owner:INST OF CHEM CHINESE ACAD OF SCI

An ultra-low field magnetic imaging device for living small animals

The invention relates to an ultra-low-field magnetic imaging device for small living animals, which belongs to the technical field of magnetic imaging, and solves the problems in the prior art that the ultra-low-field magnetic imaging device has a complex structure and is not suitable for scanning large-sized and small animals in vivo . The ultra-low-field magnetic imaging device of the present invention includes a push unit and a magnetometer unit, and the push unit includes a scanning displacement platform, a push rod and an object stage; the scanning displacement stage, the push rod, and the object stage are connected in sequence; the described The magnetometer unit includes a magnetic shield, a scanning channel, an optical channel, an atomic gas pool, and a laser light source and a detector. The scanning channel runs through the side of the magnetic shield, and the atomic gas pool is arranged on one side of the scanning channel. The detector is placed outside the magnetic shield and at one end of the optical channel. The ultra-low-field magnetic imaging device of the present invention has a simple structure, is convenient to assemble and disassemble, and is suitable for scanning large-sized and small animals in vivo on the premise of ensuring ultra-low-field detection sensitivity.
Owner:INST OF CHEM CHINESE ACAD OF SCI +1

Ultra-low field nuclear magnetic resonance spectrometer and measurement method

The invention provides an ultra-low field nuclear magnetic resonance spectrometer, comprising: a pre-polarization module suitable for pre-polarization of a nuclear magnetic resonance sample; the sample transportation device comprises a transportation pipe and is suitable for a sample pipe in which a nuclear magnetic resonance sample is packaged, and the nuclear magnetic resonance sample moves in the transportation pipe; the pulse control module is suitable for applying a pulse magnetic field to the pre-polarized nuclear magnetic resonance sample; the signal detection module is suitable for detecting a magnetic field generated by the nuclear magnetic resonance sample; the main control module is suitable for executing time sequence control on the operation of the ultra-low field nuclear magnetic resonance spectrometer and collecting and analyzing a magnetic field generated by the nuclear magnetic resonance sample; the sample conveying device further comprises a guide coil which is suitable for generating a uniform guide field so as to control the magnetic field environment where the nuclear magnetic resonance sample is located when the nuclear magnetic resonance sample moves. The invention further provides a nuclear magnetic resonance measurement method.
Owner:UNIV OF SCI & TECH OF CHINA

Ultra-low field magnetic resonance imaging system

The invention relates to the technical field of medical equipment, and discloses an ultra-low field magnetic resonance imaging system. The system comprises a magnet device, an electrical device, a radio frequency device and an induction device. The magnet device comprises at least four magnetic conductive columns, an upper magnet rack, an upper magnet assembly, a lower magnet rack and a lower magnet assembly; the at least four magnetic conductive columns are fixed between the upper magnet rack and the lower magnet rack; the upper magnet assembly is arranged at the lower part of the upper magnet rack; the lower magnet assembly is arranged at the upper part of the lower magnet rack and is opposite to the upper magnet assembly; an accommodating space for accommodating a radio frequency device is formed between the upper magnet assembly and the lower magnet assembly, and at least one channel for communicating the accommodating space with the outside is formed among the at least four magnetic conductive columns; and the electrical device is electrically connected with the upper magnet assembly, the lower magnet assembly, the radio frequency device and the induction device. The ultra-low field magnetic resonance imaging system provided by the invention is good in openness and can be used for scanning a plurality of parts.
Owner:HANGZHOU WEIYING MEDICAL TECH CO LTD

Cooling device and system, and magnetic resonance equipment

The invention discloses a cooling device and system, and magnetic resonance equipment. The cooling device is applied to low-field magnetic resonance imaging, and is characterized by comprising: a radio frequency device provided with a radio frequency transceiving coil and a radio frequency amplifier; a first cooler which is connected with the radio frequency device and is used for reducing the temperature of the radio frequency device to a first cooling temperature; and a second cooler which is arranged in the first cooler, is connected with the radio frequency transceiving coil and the radio frequency amplifier, is used for cooling the radio frequency transceiving coil and the radio frequency amplifier to a second cooling temperature, and can provide a low-temperature environment for the radio frequency coil in magnetic resonance imaging. The signal-to-noise ratio of a signal obtained through magnetic resonance imaging is improved, a clearer and more accurate magnetic resonance imaging image is further provided, the device can be applied to low-field and ultra-low-field magnetic resonance imaging, and the signal-to-noise ratio of the obtained signal can be further improved due to the fact that the magnetic field intensity of low-field and ultra-low-field magnetic resonance is low.
Owner:成都易检医疗科技有限公司

Determining position of magnetic resonance data with respect to magnetic field sensors

According to an example aspect of the present invention, there is provided generating, Low-Field-Magnetic Resonance Imaging, LF-MRI, or Ultra-Low-Field Magnetic Resonance Imaging, ULF-MRI, data with respect to an image frame, determining a sensorwise agreement of the data with determined sensitivity profiles, and determining a mapping between the image frame and a sensor frame, such that the sensorwise agreement has been fulfilled.
Owner:AALTO UNIVERSITY FOUDATION SR

Power frequency noise-suppression device based on SQUID two-order gradient meters

The invention provides a power frequency noise-suppression device based on SQUID two-order gradient meters. The power frequency noise-suppression device is applied to an ultra-low field nuclear magnetic resonance system. The power frequency noise-suppression device comprises a Dewar, a first SQUID two-order gradient meter, a second SQUID two-order gradient meter and a reading circuit, wherein the first SQUID two-order gradient meter and the second SQUID two-order gradient meter are both arranged in the Dewar; the diameter of the second SQUID two-order gradient meter is less than or equal to the diameter of the first SQUID two-order gradient meter; the first SQUID two-order gradient meter is used for detecting a nuclear magnetic resonance signal in the ultra-low field nuclear magnetic resonance system; the second SQUID two-order gradient meter is used for detecting a power frequency noise in an environmental magnetic field; and the reading circuit is used for reading out the output voltages of the first SQUID two-order gradient meter and the second SQUID two-order gradient meter, processing the output voltages and acquiring the nuclear magnetic resonance signal after the power frequency noise suppression. The power frequency noise-suppression device based on the SQUID two-order gradient meters, provided by the invention, can effectively suppress the power frequency noise interference and can increase the signal-to-noise ratio of the nuclear magnetic resonance signal.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Systems and methods for ultralow field relaxation dispersion

A system of field cycled magnetic resonance system and a method of operating a field cycled magnetic resonance system are described. In accordance with various embodiments, the disclosed system includes a static field magnet, wherein the magnet is configured to provide a low static external magnetic field to a given field of view, a radio frequency coil, and a field cycling magnet. In accordance with various embodiments, the method includes providing a static field magnet configured to image a tissue sample within a given field of view, applying a low static external magnetic field to the given field of view, providing a radio frequency coil configured to produce cycling radio frequency field, providing a field cycling magnet, altering the low static external magnetic field within the given field of view, and collecting images from the system.
Owner:PROMAXO INC

Superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI)

The invention relates to a superconducting quantum interference device (SQUID) cooling device of handheld ultra low field magnetic resonance imaging (MRI). The SQUID cooling device comprises a cooling head and a cooling conduit, wherein the cooling head is connected with an external cooling device through the cooling conduit. Ultra low temperature suitable for the operation of an SQUID is acquired through a cold supply device and transmitted to the SQUID through the cooling conduit and the cooling head so as to provide an ultra low temperature working environment for the SQUID; because only the cooling head and partial cooling conduit need to be encapsulated, liquid helium and liquid nitrogen are not needed; because only the cooling head and the cooling conduit need to be encapsulated, the cooling device has simple and practical structure, and saves the operation and maintenance costs; and the device is suitable to be used as the cooling device for the SQUID of the handheld ultra low field MRI. A cooling capsule is arranged, and one of the cooling capsule and an external refrigerating device can be selectively used; under the condition that the external refrigerating device is started, the used cooling capsule can be inserted into the installation cavity of the cooling capsule; and through the external refrigerating device, the coolant in the cooling capsule is newly liquefied, so that the cooling capsule can be recycled.
Owner:SHANTOU DONGFANG ULTRASONIC TECH
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