The invention discloses a two-dimensional material-based flower-shaped VS2@ Ti3C2 nano composite material, which is characterized in that nano flower-shaped VS2 is used as a load, and a two-dimensional Ti3C2 nanosheet is used as a matrix material, so that a stable three-dimensional space structure is formed; the two-dimensional Ti3C2 nanosheet is a nanosheet with the sheet diameter of about 1.0-2.0 [mu] m and the thickness of about 50-100 nm, and the nanoflower-shaped VS2 uniformly grows on the two-dimensional Ti3C2 nanosheet to form a stable carrying structure. The invention further discloses a preparation method of the nano composite material, and the preparation method is high in feasibility, simple in preparation process and high in repeatability. The invention also provides an application of the nano composite material in photo-thermal seawater desalination. The solar photo-thermal conversion material layer has the advantages of high stability, large light absorption surface area, high thermal efficiency, salt accumulation resistance and the like.