128 results about "Animals diseases" patented technology

Modified and stabilized propeptides of Growth Differentiation Factor proteins, such as GDF-8 and Bone Morphogenetic Protein-11, are disclosed. Also disclosed are methods for making and using the modified propeptides to prevent or treat human or animal disorders in which an increase in muscle tissue would be therapeutically beneficial. Such disorders include muscle or neuromuscular disorders (such as amyotrophic lateral sclerosis, muscular dystrophy, muscle atrophy, congestive obstructive pulmonary disease, muscle wasting syndrome, sarcopenia, or cachexia), metabolic diseases or disorders (such as such as type 2 diabetes, noninsulin-dependent diabetes mellitus, hyperglycemia, or obesity), adipose tissue disorders (such as obesity), and bone degenerative diseases (such as osteoporosis).

The present invention relates to compositions and methods of treating a disease, such as diabetes, by implanting encapsulated biological material into a patient in need of treatment. This invention provides for the placement of biocompatible coating materials around biological materials using photopolymerization while maintaining the pre-encapsulation status of the biological materials. Several methods are presented to accomplish coating several different types of biological materials. The coatings can be placed directly onto the surface of the biological materials or onto the surface of other coating materials that hold the biological materials. The components of the polymerization reactions that produce the coatings can include natural and synthetic polymers, macromers, accelerants, cocatalysts, photoinitiators, and radiation. This invention also provides methods of utilizing these encapsulated biological materials to treat different human and animal diseases or disorders by implanting them into several areas in the body including the subcutaneous site. The coating materials can be manipulated to provide different degrees of biocompatibility, protein diffusivity characteristics, strength, and biodegradability to optimize the delivery of biological materials from the encapsulated implant to the host recipient while protecting the encapsulated biological materials from destruction by the host inflammatory and immune protective mechanisms without requiring long-term anti-inflammatory or anti-immune treatment of the host.

This invention provides aryl and heteroaryl compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention may be antagonists, or partial antagonist of factor IX and/or factor XI and thus, may be useful for inhibiting the intrinsic pathway of blood coagulation. The compounds may be useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway.

Antisense oligonucleotides specific for mammalian ACE mRNA have been identified. Administration of these oligonucleotides to animals resulted in a decrease in blood pressure, but no significant change in heart rate. Methods for discovering other oligonucleotides with the same activity are taught, as are uses of the antisense molecules for treatment of human and animal diseases.

The invention discloses an immunization cell frozen stock solution, a preparation method and an application, the immunization cell frozen stock solution contains dimethyl sulfoxide, human donor plasma and an immunization cell basic medium. The immunization cell frozen stock solution comprises the following components according to volume percentage: 5-10% of dimethyl sulfoxide, 10-90% of human donor plasma and 0.01-80% of immunization cell basic medium. According to the immunization cell frozen stock solution, no animal serum is contained, exogenous protein is not introduced, so that possibility of animal disease cause pollution is reduced; refrigeration damage of the immunization cell can be effectively avoided, physiology function and stability of biology characteristic after recovering the immunization cell can be kept, the immunization cell frozen stock solution can be directly used for clinical treatment, and is suitable for long-term refrigeration storage of human mononuclear cell and other various immunization cells.

A feed additive for increasing the resistance of animal to diseases is prepared from the fragments of the plants in pinaceae through pulverizing and extracting in hot water. Its contains polyphenol compound and polyose for regulating the balance between floras in animal's intestinal tract.

Various compositions containing transfer factor in combination with nutraceuticals are provided including transfer factor in combination with zinc and essential fatty acids and transfer factor in combination with lactic acid generating bacteria. Also provided are methods for treating animal diseases and syndromes using these compositions.

The invention discloses Bacillus subtilis capable of producing broad spectrum and efficient antibacterial peptide and an application of the Bacillus subtilis and belongs to the technical field of microorganisms, wherein the Bacillus subtilis is Bacillus subtilis BRT39 concretely with the preservation number of CGMCC NO. 5702. Antibacterial peptide in metabolic products of a BRT39 bacterial strain has stronger anti-bacterial effect, a fermentation liquor can inhibit gram positive bacteria and also has stronger inhibiting effect on multiple gram negative bacteria and fungi, and the antibacterial peptide in the fermentation liquor has strong acid-base stability, good thermal stability, strong light stability and high organic solvent tolerance. The antibacterial peptide produced by the BRT39 bacterial strain belongs to a natural antibacterial agent, has no side or toxic effect, can be used as a food preservative, a feed additive, an agricultural biological control agent and an animal disease prevention agent and has the advantages of no toxicity, no residue, no drug resistance and high safety.

The invention provides a plant extract formula for inhibiting aeromonas hydrophila, which belongs to the technical field of the development and the utilization of natural products. The formula comprises the following components in percentage by weight: 50 to 80 percent of Chinese gall, 10 to 30 percent of tea polyphenol and 5 to 15 percent of rhubarb extract. The plant extract compound formula prepared by the invention is formed by combining pure natural plant extracts, has the characteristics of significant antibacterial effect, no drug residues, no pollution to water body environments and the like, provides a new method for preventing and treating aquatic animal diseases caused by the aeromonas hydrophila, and can be used as Chinese medicament preparation and a feed additive.

The invention discloses an animal disease detection early-warning system and method based on the technology of internet of things. An animal motion detection area is defined, an animal excitation device, such as a food distributor or a water drinking system, and an RFID tag reader are arranged in the detection area, and animals wearing RFID tags are recorded and counted when entering or getting out of the detection area. When moving situations of the animals are monitored by means of the method, a user of a prewarning system can receive a message that the animals have potential health problems if the moving situations of the animals in the detection area in a period are reduced to a low level such as being lower than an alarm trigger point. The method is used for prompting to examine the animals further to find whether the animals have diseases or are infected so as to achieve the functions of early detection and treatment.

The invention relates to the field of detection of animal diseases, especially to monoclonal antibodies against the nucleocapsid protein of the porcine circovirus type 2 and a kit including the monoclonal antibody. The monoclonal kit comprises a monoclonal antibody secreted by a hybridoma cell line CCTCC No. C2014199 and/or a monoclonal antibody secreted by a hybridoma cell line CCTCC No. C2014198. The invention also provides the monoclonal antibody secreted by the hybridoma cell line CCTCC No. C2014199 and the monoclonal antibody secreted by the hybridoma cell line CCTCC No. C2014198, and provides the hybridoma cell line CCTCC No. C2014199 and the hybridoma cell line CCTCC No. C2014198.

A chemotherapeutic composition for the control of plant diseases caused by viral, bacterial, and fungal organisms is disclosed. The composition is composed essentially of a tannate complex of cupric ammonium formate in an aqueous solution combined with a surfactant to prevent precipitation and may include a buffer to enable its use in native waters. The preparation and use of the composition are disclosed.

The present invention relates to the methods for preparing synthetic guggulphospholipids, their fatty acid analogues and other bioactive molecules. The present invention relates to E-guggulsterone and Z-guggulsterone or mixture of E- and Z-guggulsterones. The present invention also provides a novel method for the preparation of E-guggulsterol and Z-guggulsterol or mixture of E- and Z-guggulsterols from a mixture of E- and Z-guggulsterones. The present invention further relates to guggulphospholipids and other bioactive molecules incorporated into complexes such as liposomes, complexes, emulsions, vesicles, micelles, and mixed micelles, which can include other active agents, such as hydrophobic or hydrophilic drugs for use, e.g., in treatment of human and animal diseases.

The invention discloses an anti-newcastle disease virus Chinese medicinal composition and a preparation method thereof and is characterized in that the Chinese medicinal composition comprises the following raw materials in part by weight: indigowoad root 5-25, honeysuckle 5-25, radix bupleuri 3-20, cyrtomium fortunei 5-15, cogongrass rhizome 4-20, scutellaria baicalensis 5-20, Cortex moutan 5-15, Agastache rugosus 4-12, Poria cocos 3-19 and Radix sophorae flavescentis 4-12. The Chinese medicinal composition can effectively prevent and treat animal diseases, purify ecological environment and provide a natural green ecological product for better serve human health and livestock breeding industry. The Chinese medicinal composition has great advantages of resisting diseases and improving immunity.

Disclosed is a method for anaerobic pyrolysis treatment of dead-of-disease livestock and municipal organic refuse, which uses an anaerobic pyrolysis device to perform a harmlessness treatment on dead-of-disease pigs, the treatment being a chemical reaction process performed in a sealed, oxygen-free, non-combustible, high-temperature state, comprising heating the bodies of pigs to a high temperature under an anaerobic state, and by the action of thermal decomposition through reactions such as vaporization, pyrolysis, dehydrogenation, thermal condensation and carbonization, evaporating the moisture from the pig bodies, converting the organics therein to combustible gases and organic carbon, and killing various types of bacteria in the bodies of the dead pigs via the high temperature. Thus, a harmlessness and reutilization treatment of the dead-of-disease livestock is achieved, and environmental pollution and propagation of fatal animal diseases, such as foot-and-mouth disease, highly pathogenic avian influenza, highly pathogenic blue-ear pig disease and swine fever are avoided. Also disclosed is a device for realizing the above-mentioned method.