The invention provides a sectional homogenizing regulating and controlling method based on original tobacco formula module splitting. The regulating and controlling method comprises the following steps: 1) determining the location of a tobacco warehouse; 2) acquiring chemical value of a sample and calculating an average value; 3) selecting regulating and controlling indexes C; 4) performing descending sort on the regulating and controlling indexes C, so that K equal diversion points of a grade proportion are obtained, wherein a new grade marking code, namely G1, G2 and so on, is formed by eachequal diversion point; 5) sequentially placing and detecting G1, G2 and so on; and dividing an interval of the chemical index C corresponding to each grade code Gi into m intervals in the warehouse by a method as follows: calculating an average weight proportion weighted chemical value MGi of the grade Gi and forming the first interval with the average value MGi as a center and delta as a step length, expanding towards two sides, and marking as Ai, Bi until Mi; and 6) calculating the number of tobacco boxes NAi, NBi until NMi of Ai, Bi until Mi of each interval as well as proportions pAi, pBiuntil pMi of each tobacco box number, so that the number of delivered tobacco boxes in each interval is W*(pAi, pBi until pMi). With the application of the regulating and controlling method, the influence of unevenness of leaf paving on homogenizing regulating and controlling is relieved.