76 results about "Oral disorder" patented technology

The invention relates to the technical field of inquiry systems, in particular to an auxiliary inquiry system for oral treatment. Comprising an oral disease knowledge graph construction and inquiry knowledge base establishment module, a patient information acquisition and preprocessing module, an AI guide type inquiry module, a symptom correlation analysis and disease preliminary auxiliary prediction module, an auxiliary inquiry report generation module and a doctor feedback interaction and model iteration optimization module. According to the method, the problems of inaccurate patient description and key symptom omission in traditional inquiry are solved by constructing the oral disease knowledge graph, designing a multi-modal information acquisition and preprocessing process, generating an AI guide type inquiry process, combining the knowledge graph and machine learning to realize preliminary auxiliary disease prediction, and establishing a strict data security mechanism; the integrity and accuracy of symptom information collection are ensured through multi-modal information collection and dynamic guide inquiry.

The invention relates to the technical field of image data processing, in particular to an oral cavity knowledge graph construction method and device, equipment and a storage medium. Preprocessing the oral CT original sectional image data based on a preset adaptive threshold method and a preset rigid registration algorithm to obtain standard image data; performing feature extraction on the standard image data based on a preset deep learning model and a preset principal component analysis method to obtain a structured feature vector; constructing the structured feature vector, the structured data and the unstructured data according to a preset entity linking method, a preset inference rule and a preset graph neural network model to obtain an optimized knowledge graph; an optimized knowledge graph is constructed through CT image preprocessing, deep learning feature extraction and multi-source data fusion, an image-to-structured knowledge conversion link is realized, and a comprehensive, reliable and convenient knowledge data support is provided for precise diagnosis and treatment of oral diseases.

The utility model relates to the technical field of laser probe fixing, and discloses a laser probe fixing device for oral disease treatment, which comprises a fixing seat, the surface of the fixing seat is rotatably connected with a telescopic main rod through a damping rotating shaft, and a telescopic auxiliary rod is inserted into the telescopic main rod. First threaded holes are formed in the surface of the telescopic main rod and the surface of the telescopic auxiliary rod correspondingly, and first fixing bolts are in threaded connection with the interiors of the first threaded holes. According to the laser probe fixing device for oral disease treatment, through cooperative arrangement of a first damping bearing, a first damping rotating block, a first adjusting rod, a second damping bearing, a second damping rotating block and a second adjusting rod, the direction of a laser probe can be adjusted through the first damping bearing and the second damping bearing during use; and the angle of the laser probe is adjusted through the first damping rotating block and the second damping rotating block, so that the effect of adjusting the direction and the angle of the laser probe is achieved.

1. The name of the design product: oral cavity scanner (Lei Kou scan). 2. The use of the design product: device for treating oral diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention belongs to the field of detection and analysis, and particularly relates to a sensing electrode for diagnosing oral diseases, which comprises an electrode layer and a signal conversion layer positioned on one side of the electrode layer, a biological recognition probe is fixed on the surface and / or inside the side, far away from the electrode layer, of the signal conversion layer, and the side, far away from the electrode layer, of the signal conversion layer is further connected with a surfactant. The invention further relates to a preparation method and application of the sensing electrode. The sensing electrode is high in accuracy and reliability of detecting index components in a sample, good in repeatability and high in sensitivity.

The invention discloses an oral disease detection method based on an artificial intelligence large model, and relates to the technical field of oral detection, and the method comprises the following steps: achieving oral image enhancement through adaptive reflection suppression and non-uniform illumination correction; pathological and environmental features are extracted by using a double-flow network, and orthogonal constraint is applied to enforce feature independence; a gradient inversion layer is introduced into the multi-scale environment discriminator, and feature separation is realized through confrontation loss; the pathological features and the environmental suppression features are fused, and a lesion area is enhanced in combination with cross-scale attention weight; and generating a disease probability and lesion segmentation mask through classification and positioning double branches. Through a feature space decoupling mechanism, pathological features and environmental interference features are orthogonally separated in a potential space, and errors caused by light reflection, saliva shielding or instrument interference can be prevented; the two-channel adversarial training forces the network learning environment to be unchanged pathological representation, so that the model keeps stable recognition performance in a real clinical scene.

Disclosed in the present invention are an antibacterial electric toothbrush based on a pulsed ultrasonic piezoelectric response principle, and an antibacterial method. The electric toothbrush in the present invention comprises a toothbrush head and a driving mechanism for driving the toothbrush head to vibrate, wherein the driving mechanism is configured to generate low-intensity pulsed ultrasonic waves, and the toothbrush head is provided with piezoelectric bristles and enhances the electric responsiveness of the piezoelectric bristles by means of ultrasonic vibration, such that a good antibacterial effect is achieved. The provided electric toothbrush can not only effectively inhibit the growth of bacteria on a standing toothbrush head, but also has improved antibacterial activity during a tooth-brushing operation process, such that dental plaque can be effectively inhibited, and oral diseases, such as periodontitis, can be effectively prevented.

The invention provides an oral disease diagnosis and treatment question-answering method, device, equipment, medium and product, and relates to the technical field of diagnosis and treatment question-answering, the method comprises the following steps: obtaining an oral disease question input by a user, and determining a query sub-graph based on the oral disease question; querying sub-graph characterization structured oral disease problems; matching the query sub-graph with the oral medical knowledge graph, and determining a complete sub-graph corresponding to the query sub-graph according to a matching result; the oral medical knowledge graph is constructed based on multi-source heterogeneous diagnosis and treatment text data in the field of oral diseases; inputting the complete sub-graph and the oral disease question into a diagnosis and treatment big language model to obtain an oral disease diagnosis and treatment answer corresponding to the oral disease question output by the diagnosis and treatment big language model; the diagnosis and treatment big language model is obtained by training a general big language model based on oral disease diagnosis and treatment sample data. According to the technical scheme, professional nouns and complex relations in the field of oral diseases can be accurately represented, and the accuracy and interpretability of diagnosis and treatment answers are improved.

The utility model discloses a magnetic suspension type telescopic motor structure of an electric toothbrush handle, which relates to the technical field of electric toothbrushes, and comprises a shell and a hair planting round head, one end of the shell is fixedly connected with the hair planting round head, a support is fixedly connected inside the shell, one end of the support is fixedly connected with an electromagnetic generator assembly, and the electromagnetic generator assembly is fixedly connected with the shell. One side of the support is provided with a transmission shaft connected with the electromagnetic generator assembly, the other end of the transmission shaft is fixedly sleeved with a waterproof shaft sleeve, one side of the waterproof shaft sleeve is provided with a shaft cap, one end of the transmission shaft is located in the shaft cap, and the outer side wall of the shaft cap is fixedly connected with an inner shaft through a spring. Through magnetic energy driving and low-friction design, efficient swinging of the brush head is ensured, the cleaning effect is improved, meanwhile, energy loss and part abrasion are reduced, the service life is prolonged, and oral diseases are effectively prevented.

The present invention provides a method and system for diagnosing oral diseases in companion animals, the method being performed by a health management server and including the steps of: generating health standard data by matching basic condition information and basic result data; receiving condition measurement information of a test subject from a user terminal; and generating health result data by comparing and analyzing the condition measurement information based on the health standard data, wherein the generating health standard data can include the steps of preprocessing images included in basic radiography information included in the basic condition information; extracting analyzable analysis images from the preprocessed images; extracting region-specific analysis images for a plurality of disease analyses from the analysis images and diagnosing the presence or absence of oral diseases for the region-specific analysis images to generate basic diagnosis data; determining disease progression stages for the region-specific analysis images based on the basic diagnosis data to generate basic assessment data; and generating basic result data including the basic diagnosis data and the basic assessment data corresponding to the basic diagnosis data.

This invention relates to the field of medical device technology and provides a flexible self-powered oral diagnostic and treatment device and its preparation method. The device includes a flexible conductive porous microneedle, a flexible microfluidic module, a flexible triboelectric nanogenerator, and a flexible transparent dental crown. The flexible conductive porous microneedle is used to extract gingival crevicular fluid, and its surface has multiple rings of needles at different heights. The flexible microfluidic module incorporates a microchannel structure and a detection unit to analyze biomarkers in the gingival crevicular fluid. The flexible triboelectric nanogenerator converts the mechanical energy of oral motion into electrical energy to provide exogenous electrical stimulation and achieve electrically controlled drug release. This device enables real-time monitoring, diagnosis, and treatment of the oral microenvironment, and has advantages such as self-powered operation, good fit, and discreet comfort, making it suitable for closed-loop management of oral diseases such as periodontitis.

This invention belongs to the field of pharmaceutical technology for the treatment and prevention of oral diseases, and particularly relates to a porphyrin and ferrocene derivative, nanoparticles, preparation methods, and applications of synergistic photothermal and acoustic therapy for oral diseases. The porphyrin and ferrocene derivative are formed by organically combining tetraaminophenylporphyrin and diformaldehyde ferrocene through imine dynamic covalent bonds. This invention, through innovative raw material coupling methods and functional integration design, synergistically achieves PTT-SDT dual therapy, providing a new and superior technical solution for precise, efficient, and low-drug-resistance treatment of deep oral bacterial-fungal biofilm infections.

The invention provides an oral disease diagnosis method based on multi-path feature extraction and frequency enhancement, and relates to the technical field of oral medical treatment, and the method employs a space channel to cooperate with attention enhancement feature extraction, improves the representation of a network on image features, employs a full-dimensional dynamic convolution kernel, employs a three-branch parallel structure to combine with a frequency enhancement technology, and achieves the diagnosis of oral diseases. The collaborative modeling of global and local features of the network is improved, the perceptual ability of edge information is enhanced, difficult sample learning is enhanced through an adaptive threshold focus loss function, the problem of sample imbalance is improved, rare disease focuses with limited sample sizes and low-resolution images are more sensitive, and the detection result is more accurate.

There is provided a compound of formula I, X-Y (I) wherein: Y comprises a peptide fragment of formula IV, [Ala] m-[Lys-V] n-Lys-V (IV) wherein m represents 0 or 1, n represents the integer 0, 1, 2, 3 or 4, and each V independently represents a sequence of 2 to 4 amino acids wherein the amino acids are selected from one or more of the group consisting of Lys, Pro, Hyp, diHyp, Thr, pThr, DOPA, Tyr and Ser; and X represents at least one optional substituent selected from the group consisting of: (i) a lipid selected from the group consisting of vitamin A, vitamin E, cholesterol and fatty acids comprising one or more carboxylic acid groups, 1 to 50 carbons and / or one or more cyclic rings, said lipids being linear or branched, saturated or unsaturated with between 1 and 10 carbon-carbon double bonds and / or substituted with between 1 and 10-OH groups, or a derivative of any of these lipids; and / or (ii) a non-steroidal anti-inflammatory agent, which compounds may be used in medicine, including as pharmaceutical excipients, adhesives and film-forming materials, and / or may be used in the treatment of conditions characterized by inflammation, including wounds, burns and mucosal disorders such as skin diseases, oral diseases, gynecological diseases and IBD.

The invention relates to the technical field related to oral treatment and diagnosis, and discloses a 3D modeling assisted oral disease diagnosis platform which comprises a three-dimensional scanning device, a multi-source data fusion module and a biomechanical simulation engine. According to the invention, an oral cavity digital model is constructed through three-dimensional scanning and real-time modeling, and multi-modal data analysis and a deep learning algorithm are integrated, so that automatic identification and quantitative evaluation of a focus are realized; through cooperation of a three-dimensional scanning device, a multi-source data fusion module, a biomechanical simulation engine, an AI focus diagnosis module and a visualization terminal, the problems of insufficient three-dimensional visualization, low early-stage lesion recognition rate, low diagnosis efficiency and poor result consistency of oral disease diagnosis can be effectively solved; therefore, efficient and accurate oral disease diagnosis and judgment and subsequent continuous treatment are achieved, real-time three-dimensional modeling and multi-scale lesion analysis are integrated on the same platform for the first time, and diagnosis accuracy is improved through geometric + gray bimodal data.

An orally administrable composition for maintaining oral health comprising as active ingredients an antibiotic agent, an anti-inflammatory agent and optionally a remineralizing agent is disclosed. Methods of using the composition for maintaining or improving oral health and for treating oral diseases or conditions by self-administration or by administration by a health care professional are also provided.

The application discloses a kind of self-assembled polypeptide TKH and its application, belong to the field of biological medicine technology.The amino acid sequence of polypeptide TKH is as follows:TKRQQVVGLLWHLLHHLLHGKGTKRQQVVGLLWH LLHHLLH.The composition of the application includes self-assembled polypeptide TKH, polypeptide derivative or polypeptide pharmaceutically acceptable salt, ester, and pharmaceutically acceptable adjuvant.The application further discloses the application of self-assembled polypeptide TKH, polypeptide derivative or its pharmaceutically acceptable salt or ester in preparing oral care composition for dental hard tissue remineralization, and in preparing medical material for treating or preventing oral diseases.The self-assembled polypeptide TKH of the application shows significantly enhanced self-assembly ability, liquid phase separation behavior and hydroxyapatite adsorption characteristics, not only has more excellent remineralization performance, but also can simultaneously inhibit streptococcus mutans biofilm formation and acid production activity.

1. Name of the Design Product: Semiconductor Laser Therapeutic Apparatus (CHEESE+). 2. Use of the Design Product: Treating oral diseases with semiconductor laser. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Indicates the Design Key Points: Perspective view.

The utility model relates to the technical field of medical instruments, and discloses a medical ice-cream stick for oral cavity cryotherapy, which comprises an oral cavity treatment sterile liquid medicine frozen ice block and a bearing bracket, and the oral cavity treatment sterile liquid medicine frozen ice block is fixed on the bearing bracket after being frozen; the bearing bracket comprises an ice block core rod and a handle; the ice block core rod is a hollow thin-wall cylinder, and a plurality of through holes are formed in the thin wall of the ice block core rod; the ice block core rod of the bearing support and the handle are integrally formed in an injection molding mode through medical plastics. The structural design of the bearing support and the sterile frozen ice block is improved, so that the sterile frozen ice block can meet the sterile requirement, the melting time of the whole ice block is greatly prolonged, the use standard of clinical medical instruments can be met, wound liquid medicine infiltration and freezing therapy can be implemented, and the sterile frozen ice block is used for treating various oral diseases of patients. And the use experience of the patient is improved.

According to the toothbrush detection device and method, a mechanical arm and a carrier platform are used for controlling a to-be-detected toothbrush to execute the tooth brushing process, an image collecting device is used for collecting images in the tooth brushing process, and a processor detects the cleaning force effect of the to-be-detected toothbrush according to image detection to obtain a detection result. The cleaning capacity of the toothbrush to be detected is quantified according to the detection result, and the cleaning effect aiming at the tooth target part is introduced, so that the detection result can reflect the capacity of the toothbrush to be detected for preventing or relieving specific oral diseases. Besides, in the implementation mode of the specification, the whole detection process is standardized, long-term observation and test on a large number of subjects are not needed, the detection efficiency is improved, and the detection cost is reduced.

This invention relates to a traditional Chinese medicine composition for treating oral diseases and its preparation method, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for treating oral diseases is composed of *Clerodendrum trichotomum* and *Radix Araliae*. This invention discovers that the combined use of *Clerodendrum trichotomum* and *Radix Araliae*, with their synergistic effect, significantly improves the therapeutic effect of the resulting composition on oral diseases such as oral ulcers. This not only broadens the application range of *Clerodendrum trichotomum* and *Radix Araliae*, but also provides a new approach to the treatment of oral diseases.

The invention discloses oxidation responsive hydrogel carrying Chinese wolfberry glycopeptide as well as a preparation method and application of the oxidation responsive hydrogel, and belongs to the technical field of biological medicines. The oxidation responsive hydrogel comprises in-situ hydrogel and oxidation responsive microspheres embedded in the in-situ hydrogel, wherein the in-situ hydrogel is formed by crosslinking a hydrogel bracket component A and a component B; the oxidation responsive microsphere comprises a gelatin network formed by crosslinking gelatin and an oxidation responsive cross-linking agent, and wolfberry glycopeptide wrapped by the gelatin network. The invention further discloses a preparation method of the oxidation responsive hydrogel carrying the lycium barbarum glycopeptide and application of the oxidation responsive hydrogel in preparation of drugs for preventing or / and treating oral diseases, the oxidation hydrogel can be slowly released in a high-active oxygen pathological environment, the drug retention time is prolonged, and the treatment effect is improved.

The application discloses application of plasma-derived exosomes in preparation of drugs for improving or treating oral diseases. The plasma-derived exosomes have good biological effects of inhibiting inflammation, promoting angiogenesis and accelerating lesion healing, can accelerate healing of mucosal injury by inhibiting release of inflammatory factors and chemotactic factors, and thus reduce progress of inflammation. In addition, the plasma-derived exosomes can promote proliferation of human oral epithelial cells and healing of scratches, and have good effects in improving oral diseases.

The invention discloses a system for treating oral diseases through a pulsed electric field, according to at least one preset energy output algorithm, at least one target energy packet corresponding to the preset energy output algorithm is generated, and different types of oral lesion tissues can be more flexibly, accurately and selectively treated through the target energy packet; moreover, when the energy of the target energy packet is utilized to ablate pathological cells, extracellular matrixes are not damaged, and protein denaturation is not generated, so that obvious scars or tissue ablation traces are not caused to tissues; at the same time, treatment by non-thermal methods can maintain the collagen structure in the oral cavity, allowing the regeneration of healthy oral mucosa with normative healthy tissues.

This invention relates to the field of intelligent diagnostic technology for oral medical imaging, specifically an intelligent auxiliary diagnostic system for oral diseases integrating multimodal imaging. The system includes: a data receiving module that receives intraoral optical photographs, cone-beam CT, and oral and maxillofacial MRI; an image analysis module that automatically delineates and segments the optical photographs to generate two-dimensional structural maps with tooth position markers, reconstructs a three-dimensional jawbone from CBCT and extracts root canal structures to generate a model containing bone density and root canal parameters, and enhances soft tissue from MRI and identifies inflammatory areas to generate a model showing muscles, blood vessels, nerves, and inflammatory boundaries; a multimodal fusion module that uses spatial registration and feature fusion to construct a unified digital model; and an intelligent diagnostic module that calls a pre-trained model for analysis and reasoning to generate a disease list and quantitative parameters. Through differentiated image processing and multimodal fusion, the system achieves a panoramic presentation of oral structure and lesions, enhancing the comprehensiveness of disease identification. This invention can improve the accuracy and efficiency of intelligent auxiliary diagnosis of oral diseases.

The present invention relates to the technical field of stomatology. Disclosed is an oral disease detection method based on a large artificial intelligence model. The method comprises: acquiring a dental lesion image and a corresponding intraoral state description; using a feature extraction module BERT and a multi-scale feature extraction module (MFEM) to respectively extract text feature information of an intraoral state and image feature information of the dental lesion image; identifying and excluding false negative samples therein; introducing a total loss function and a dynamic label assignment strategy into a YOLOv8 network to obtain an improved YOLOv8 network; dividing a data set into a training set and a test set, and sequentially inputting the training set and the test set into the improved YOLOv8 network for validation, so as to obtain a validated YOLOv8 network; and inputting the dental lesion image and the corresponding text information into the validated YOLOv8 network, so as to obtain lesion region type detection and a text description. The present invention can effectively improve the detection and classification of various intraoral diseases, and can give corresponding lesion region descriptions and suggestions.

The application relates to the technical field of oral cavity medical instruments, in particular to a control method of an oral cavity scanner, the oral cavity scanner and a storage medium, which can be applied to the examination of oral cavity diseases and oral cavity treatment. The oral cavity scanner comprises a holding part for an operator to hold, an extension part detachably installed on the holding part and used for entering the oral cavity of a subject, the extension part comprises a mirror, the holding part comprises a light projector used for projecting light to the side of the mirror and a camera used for acquiring an image of the side of the mirror, and the control method comprises the following steps: the light projector is caused to project structured light with a first projection area, and the first image is acquired by using the camera, wherein the mirror is entirely within the first projection area; based on the first image, the position and size information of the mirror are determined; based on the position and size information, the light projector is caused to project planar light with a second projection area, and the second image is acquired by using the camera, wherein the second projection area is entirely within the mirror.

Provided are a saliva glucose test strip with extended room temperature storage time, and a preparation method therefor, a test method thereof and a use thereof. The saliva glucose test strip comprises: glucose oxidase, horseradish peroxidase, a vitamin C oxidase solution, a chromogenic agent, an enzyme / protein protectant, an enzyme stabilizer, and a sodium alginate solution. The storage time of the test strip at room temperature is extended by adding reagents. The saliva glucose test strip has important clinical significance in early prevention, preliminary diagnosis, treatment, and like of diabetes and oral diseases.

The invention discloses a self-assembled polypeptide TKH and application thereof, and belongs to the technical field of biological medicine. The amino acid sequence of the polypeptide TKH is as follows: TKRQVVVGLLWHLLHHLLHGKGTKRQVVVGL LWHLLHHLLH. The amino acid sequence of the polypeptide TKH is as follows: TKRQVVVGL LWHLLHHLLH. The composition disclosed by the invention comprises self-assembled polypeptide TKH, polypeptide derivatives or pharmaceutically acceptable salts and esters of polypeptide, and pharmaceutically acceptable auxiliary materials. The invention also discloses an application of the self-assembled polypeptide TKH, the polypeptide derivative or the pharmaceutically acceptable salt or ester thereof in preparation of an oral care composition for tooth hard tissue remineralization, and an application in preparation of a medical material for treating or preventing oral diseases. The self-assembled polypeptide TKH shows significantly enhanced self-assembly ability, liquid phase separation behavior and hydroxyapatite adsorption characteristic, not only has more excellent remineralization performance, but also can synchronously inhibit streptococcus mutans biofilm formation and acid production activity.