46 results about "Oral disorder" patented technology

The invention relates to the technical field of inquiry systems, in particular to an auxiliary inquiry system for oral treatment. Comprising an oral disease knowledge graph construction and inquiry knowledge base establishment module, a patient information acquisition and preprocessing module, an AI guide type inquiry module, a symptom correlation analysis and disease preliminary auxiliary prediction module, an auxiliary inquiry report generation module and a doctor feedback interaction and model iteration optimization module. According to the method, the problems of inaccurate patient description and key symptom omission in traditional inquiry are solved by constructing the oral disease knowledge graph, designing a multi-modal information acquisition and preprocessing process, generating an AI guide type inquiry process, combining the knowledge graph and machine learning to realize preliminary auxiliary disease prediction, and establishing a strict data security mechanism; the integrity and accuracy of symptom information collection are ensured through multi-modal information collection and dynamic guide inquiry.

The invention relates to the technical field of image data processing, in particular to an oral cavity knowledge graph construction method and device, equipment and a storage medium. Preprocessing the oral CT original sectional image data based on a preset adaptive threshold method and a preset rigid registration algorithm to obtain standard image data; performing feature extraction on the standard image data based on a preset deep learning model and a preset principal component analysis method to obtain a structured feature vector; constructing the structured feature vector, the structured data and the unstructured data according to a preset entity linking method, a preset inference rule and a preset graph neural network model to obtain an optimized knowledge graph; an optimized knowledge graph is constructed through CT image preprocessing, deep learning feature extraction and multi-source data fusion, an image-to-structured knowledge conversion link is realized, and a comprehensive, reliable and convenient knowledge data support is provided for precise diagnosis and treatment of oral diseases.

1. The name of the design product: oral cavity scanner (Lei Kou scan). 2. The use of the design product: device for treating oral diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention belongs to the field of detection and analysis, and particularly relates to a sensing electrode for diagnosing oral diseases, which comprises an electrode layer and a signal conversion layer positioned on one side of the electrode layer, a biological recognition probe is fixed on the surface and / or inside the side, far away from the electrode layer, of the signal conversion layer, and the side, far away from the electrode layer, of the signal conversion layer is further connected with a surfactant. The invention further relates to a preparation method and application of the sensing electrode. The sensing electrode is high in accuracy and reliability of detecting index components in a sample, good in repeatability and high in sensitivity.

The utility model discloses a magnetic suspension type telescopic motor structure of an electric toothbrush handle, which relates to the technical field of electric toothbrushes, and comprises a shell and a hair planting round head, one end of the shell is fixedly connected with the hair planting round head, a support is fixedly connected inside the shell, one end of the support is fixedly connected with an electromagnetic generator assembly, and the electromagnetic generator assembly is fixedly connected with the shell. One side of the support is provided with a transmission shaft connected with the electromagnetic generator assembly, the other end of the transmission shaft is fixedly sleeved with a waterproof shaft sleeve, one side of the waterproof shaft sleeve is provided with a shaft cap, one end of the transmission shaft is located in the shaft cap, and the outer side wall of the shaft cap is fixedly connected with an inner shaft through a spring. Through magnetic energy driving and low-friction design, efficient swinging of the brush head is ensured, the cleaning effect is improved, meanwhile, energy loss and part abrasion are reduced, the service life is prolonged, and oral diseases are effectively prevented.

The present invention provides a method and system for diagnosing oral diseases in companion animals, the method being performed by a health management server and including the steps of: generating health standard data by matching basic condition information and basic result data; receiving condition measurement information of a test subject from a user terminal; and generating health result data by comparing and analyzing the condition measurement information based on the health standard data, wherein the generating health standard data can include the steps of preprocessing images included in basic radiography information included in the basic condition information; extracting analyzable analysis images from the preprocessed images; extracting region-specific analysis images for a plurality of disease analyses from the analysis images and diagnosing the presence or absence of oral diseases for the region-specific analysis images to generate basic diagnosis data; determining disease progression stages for the region-specific analysis images based on the basic diagnosis data to generate basic assessment data; and generating basic result data including the basic diagnosis data and the basic assessment data corresponding to the basic diagnosis data.

This invention relates to the field of medical device technology and provides a flexible self-powered oral diagnostic and treatment device and its preparation method. The device includes a flexible conductive porous microneedle, a flexible microfluidic module, a flexible triboelectric nanogenerator, and a flexible transparent dental crown. The flexible conductive porous microneedle is used to extract gingival crevicular fluid, and its surface has multiple rings of needles at different heights. The flexible microfluidic module incorporates a microchannel structure and a detection unit to analyze biomarkers in the gingival crevicular fluid. The flexible triboelectric nanogenerator converts the mechanical energy of oral motion into electrical energy to provide exogenous electrical stimulation and achieve electrically controlled drug release. This device enables real-time monitoring, diagnosis, and treatment of the oral microenvironment, and has advantages such as self-powered operation, good fit, and discreet comfort, making it suitable for closed-loop management of oral diseases such as periodontitis.

This invention belongs to the field of pharmaceutical technology for the treatment and prevention of oral diseases, and particularly relates to a porphyrin and ferrocene derivative, nanoparticles, preparation methods, and applications of synergistic photothermal and acoustic therapy for oral diseases. The porphyrin and ferrocene derivative are formed by organically combining tetraaminophenylporphyrin and diformaldehyde ferrocene through imine dynamic covalent bonds. This invention, through innovative raw material coupling methods and functional integration design, synergistically achieves PTT-SDT dual therapy, providing a new and superior technical solution for precise, efficient, and low-drug-resistance treatment of deep oral bacterial-fungal biofilm infections.

There is provided a compound of formula I, X-Y (I) wherein: Y comprises a peptide fragment of formula IV, [Ala] m-[Lys-V] n-Lys-V (IV) wherein m represents 0 or 1, n represents the integer 0, 1, 2, 3 or 4, and each V independently represents a sequence of 2 to 4 amino acids wherein the amino acids are selected from one or more of the group consisting of Lys, Pro, Hyp, diHyp, Thr, pThr, DOPA, Tyr and Ser; and X represents at least one optional substituent selected from the group consisting of: (i) a lipid selected from the group consisting of vitamin A, vitamin E, cholesterol and fatty acids comprising one or more carboxylic acid groups, 1 to 50 carbons and / or one or more cyclic rings, said lipids being linear or branched, saturated or unsaturated with between 1 and 10 carbon-carbon double bonds and / or substituted with between 1 and 10-OH groups, or a derivative of any of these lipids; and / or (ii) a non-steroidal anti-inflammatory agent, which compounds may be used in medicine, including as pharmaceutical excipients, adhesives and film-forming materials, and / or may be used in the treatment of conditions characterized by inflammation, including wounds, burns and mucosal disorders such as skin diseases, oral diseases, gynecological diseases and IBD.

An orally administrable composition for maintaining oral health comprising as active ingredients an antibiotic agent, an anti-inflammatory agent and optionally a remineralizing agent is disclosed. Methods of using the composition for maintaining or improving oral health and for treating oral diseases or conditions by self-administration or by administration by a health care professional are also provided.

The application discloses a kind of self-assembled polypeptide TKH and its application, belong to the field of biological medicine technology.The amino acid sequence of polypeptide TKH is as follows:TKRQQVVGLLWHLLHHLLHGKGTKRQQVVGLLWH LLHHLLH.The composition of the application includes self-assembled polypeptide TKH, polypeptide derivative or polypeptide pharmaceutically acceptable salt, ester, and pharmaceutically acceptable adjuvant.The application further discloses the application of self-assembled polypeptide TKH, polypeptide derivative or its pharmaceutically acceptable salt or ester in preparing oral care composition for dental hard tissue remineralization, and in preparing medical material for treating or preventing oral diseases.The self-assembled polypeptide TKH of the application shows significantly enhanced self-assembly ability, liquid phase separation behavior and hydroxyapatite adsorption characteristics, not only has more excellent remineralization performance, but also can simultaneously inhibit streptococcus mutans biofilm formation and acid production activity.

According to the toothbrush detection device and method, a mechanical arm and a carrier platform are used for controlling a to-be-detected toothbrush to execute the tooth brushing process, an image collecting device is used for collecting images in the tooth brushing process, and a processor detects the cleaning force effect of the to-be-detected toothbrush according to image detection to obtain a detection result. The cleaning capacity of the toothbrush to be detected is quantified according to the detection result, and the cleaning effect aiming at the tooth target part is introduced, so that the detection result can reflect the capacity of the toothbrush to be detected for preventing or relieving specific oral diseases. Besides, in the implementation mode of the specification, the whole detection process is standardized, long-term observation and test on a large number of subjects are not needed, the detection efficiency is improved, and the detection cost is reduced.

This invention relates to a traditional Chinese medicine composition for treating oral diseases and its preparation method, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for treating oral diseases is composed of *Clerodendrum trichotomum* and *Radix Araliae*. This invention discovers that the combined use of *Clerodendrum trichotomum* and *Radix Araliae*, with their synergistic effect, significantly improves the therapeutic effect of the resulting composition on oral diseases such as oral ulcers. This not only broadens the application range of *Clerodendrum trichotomum* and *Radix Araliae*, but also provides a new approach to the treatment of oral diseases.

The invention discloses oxidation responsive hydrogel carrying Chinese wolfberry glycopeptide as well as a preparation method and application of the oxidation responsive hydrogel, and belongs to the technical field of biological medicines. The oxidation responsive hydrogel comprises in-situ hydrogel and oxidation responsive microspheres embedded in the in-situ hydrogel, wherein the in-situ hydrogel is formed by crosslinking a hydrogel bracket component A and a component B; the oxidation responsive microsphere comprises a gelatin network formed by crosslinking gelatin and an oxidation responsive cross-linking agent, and wolfberry glycopeptide wrapped by the gelatin network. The invention further discloses a preparation method of the oxidation responsive hydrogel carrying the lycium barbarum glycopeptide and application of the oxidation responsive hydrogel in preparation of drugs for preventing or / and treating oral diseases, the oxidation hydrogel can be slowly released in a high-active oxygen pathological environment, the drug retention time is prolonged, and the treatment effect is improved.

The invention discloses a system for treating oral diseases through a pulsed electric field, according to at least one preset energy output algorithm, at least one target energy packet corresponding to the preset energy output algorithm is generated, and different types of oral lesion tissues can be more flexibly, accurately and selectively treated through the target energy packet; moreover, when the energy of the target energy packet is utilized to ablate pathological cells, extracellular matrixes are not damaged, and protein denaturation is not generated, so that obvious scars or tissue ablation traces are not caused to tissues; at the same time, treatment by non-thermal methods can maintain the collagen structure in the oral cavity, allowing the regeneration of healthy oral mucosa with normative healthy tissues.

This invention relates to the field of intelligent diagnostic technology for oral medical imaging, specifically an intelligent auxiliary diagnostic system for oral diseases integrating multimodal imaging. The system includes: a data receiving module that receives intraoral optical photographs, cone-beam CT, and oral and maxillofacial MRI; an image analysis module that automatically delineates and segments the optical photographs to generate two-dimensional structural maps with tooth position markers, reconstructs a three-dimensional jawbone from CBCT and extracts root canal structures to generate a model containing bone density and root canal parameters, and enhances soft tissue from MRI and identifies inflammatory areas to generate a model showing muscles, blood vessels, nerves, and inflammatory boundaries; a multimodal fusion module that uses spatial registration and feature fusion to construct a unified digital model; and an intelligent diagnostic module that calls a pre-trained model for analysis and reasoning to generate a disease list and quantitative parameters. Through differentiated image processing and multimodal fusion, the system achieves a panoramic presentation of oral structure and lesions, enhancing the comprehensiveness of disease identification. This invention can improve the accuracy and efficiency of intelligent auxiliary diagnosis of oral diseases.

The present invention relates to the technical field of stomatology. Disclosed is an oral disease detection method based on a large artificial intelligence model. The method comprises: acquiring a dental lesion image and a corresponding intraoral state description; using a feature extraction module BERT and a multi-scale feature extraction module (MFEM) to respectively extract text feature information of an intraoral state and image feature information of the dental lesion image; identifying and excluding false negative samples therein; introducing a total loss function and a dynamic label assignment strategy into a YOLOv8 network to obtain an improved YOLOv8 network; dividing a data set into a training set and a test set, and sequentially inputting the training set and the test set into the improved YOLOv8 network for validation, so as to obtain a validated YOLOv8 network; and inputting the dental lesion image and the corresponding text information into the validated YOLOv8 network, so as to obtain lesion region type detection and a text description. The present invention can effectively improve the detection and classification of various intraoral diseases, and can give corresponding lesion region descriptions and suggestions.

The application relates to the technical field of oral cavity medical instruments, in particular to a control method of an oral cavity scanner, the oral cavity scanner and a storage medium, which can be applied to the examination of oral cavity diseases and oral cavity treatment. The oral cavity scanner comprises a holding part for an operator to hold, an extension part detachably installed on the holding part and used for entering the oral cavity of a subject, the extension part comprises a mirror, the holding part comprises a light projector used for projecting light to the side of the mirror and a camera used for acquiring an image of the side of the mirror, and the control method comprises the following steps: the light projector is caused to project structured light with a first projection area, and the first image is acquired by using the camera, wherein the mirror is entirely within the first projection area; based on the first image, the position and size information of the mirror are determined; based on the position and size information, the light projector is caused to project planar light with a second projection area, and the second image is acquired by using the camera, wherein the second projection area is entirely within the mirror.

The present invention provides a method and system for diagnosing oral diseases of a companion animal. The method is a method of diagnosing oral diseases of a companion animal, which is performed by a health management server, and may comprise the steps of: generating health standard data by matching basic condition information and basic result data; receiving, from a user terminal, condition measurement information of an object to be inspected; and comparing and analyzing the condition measurement information on the basis of the health standard data to generate health result data, wherein the step of generating the health standard data comprises the steps of: preprocessing an image included in basic photographing information included in the basic condition information; extracting an analyzable analysis image from the preprocessed image; extracting, from the analysis image, site-specific analysis images for analyzing a plurality of diseases to diagnose the presence or absence of oral diseases in the site-specific analysis images, thereby generating basic diagnostic data; determining a disease-specific progression stage in the site-specific analysis images on the basis of the basic diagnostic data to generate basic determination data; and generating the basic result data including the basic diagnostic data and the basic determination data corresponding to the basic diagnostic data.

The application provides an ablation device with a stable structure, comprising an ablation assembly, a connecting catheter and a handle, wherein the ablation assembly comprises a spiral tube and an ablation electrode, the spiral tube comprises a tube starting end located in the middle and a tube tail end located on the outside, the tube starting end is connected with the distal end of the connecting catheter, and the tube tail end is fixedly connected to the side wall of the spiral tube. The electrode of the ablation device is arranged on the spiral-shaped tube, so that the treatment area is increased, the spiral design improves the fit between the skin and the product, and the ablation device is especially suitable for oral diseases which need large-area ablation treatment. The tube tail end is fixedly connected to the side wall of the spiral tube, so that the stability of the overall structure is increased, and accidents caused by the contact between the electrodes due to the shaking of the device are avoided.

1. The name of the design product: oral cavity illumination lamp. 2. The use of the design product: used for lighting when diagnosing oral cavity diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

The application provides a drug delivery method and device based on privacy protection and image recognition, which comprises the following steps: after a patient visits a doctor and purchases drugs, the prescribed dosage, drug name, oral disease name and personal information are input into a central processing device; the oral lesion images of the patient are collected by multiple terminals of the hospital and treatment institutions and the drug delivery device, and privacy protection is performed according to the number of cases; an oral positioning model is trained by federated learning, which is used for oral lesion partition positioning; a disease analysis model is trained, which is used for determining the drug dosage; the drug delivery device is initialized; the patient uses the drug delivery device to deliver drugs, and the oral lesion images are uploaded by collection; the drug delivery device establishes a patient drug delivery project, and performs expiration reminding, expiration locking and device reuse; the drug delivery device is a handheld spray drug delivery device that meets the requirements of human oral drug delivery, comprising a drug storage chamber, an image acquisition and analysis device, a drug delivery probe and an information interconnection device.

This invention relates to the field of medical device technology, and more particularly to a phototherapy device for dental implants with an automatic drug delivery function. The phototherapy device uses a medication solution and an expansion structure placed between a filter membrane and a base. In the non-treatment state, because the diameter of water molecules in the medication solution is larger than the diameter of drug molecules, and the diameter of drug molecules is larger than the micropore diameter of the filter membrane, this prevents the drug from flowing into the oral cavity through the micro-release holes. When it is necessary to release the drug into the oral cavity in conjunction with phototherapy, the patient holds warm water in their mouth to heat the expansion structure. The expansion structure expands due to heat, squeezing the medication solution. The drug molecules are squeezed by the expansion structure, and as the squeezing pressure increases, the drug molecules are forced out of the micropores of the filter membrane. The drug molecules then flow out through the micro-release holes and into the oral cavity to assist in the treatment of oral diseases using phototherapy.

The application discloses an imaging method of an oral imaging device, comprising the following steps: S1, acquiring an image sequence of not less than one view angle collected by the oral imaging device when imaging the upper jaw and / or the lower jaw; S2, extracting useful video clips of the upper jaw and the lower jaw from the image sequence, and arranging the video clips into at least two video segments corresponding to the upper jaw and the lower jaw respectively; S3, recognizing the shooting direction of the video segments by combining motion detection data with a deep learning model, and unifying the video sequence; S4, dynamically adjusting the frame extraction method of the video segments according to the motion detection data, retaining key motion node images, reconstructing the calibrated video segments into a standard sequence in a unified direction, and outputting the standard sequence, so as to perform oral three-dimensional scene reconstruction and oral disease analysis. The application also provides an oral imaging device. The application reduces the operation burden of a user, significantly reduces the operation amount of a visual algorithm, and improves the reliability of three-dimensional modeling and the accuracy of oral disease identification.

An areca nut product and preparation method thereof, and an areca nut additive agent are provided. The areca nut product is prepared from areca nuts, citric acid, mature vinegar, chitosan, active zinc oxide, monazite calcined distilled water, bovine bone protein peptide, lipase, isomaltooligosaccharide, soybean lecithin, ginseng, atractylodes macrocephala, poria cocos, liquorice, astragalus, notoginseng, tangerine peel, folium eucommiae, citronella grass, and mucor. Experimental tests shows that the areca nut product of the disclosure has a good antiviral effect, and the areca nut product has good preventive and therapeutic effects on oral diseases; compared with ordinary areca nut products, carcinogenic study has shown that carcinogenicity of the areca nut product of the disclosure has significantly reduced.

The invention discloses a targeted antibacterial tooth paste based on an enzyme specific response mechanism as well as a preparation method and application thereof. The targeted antibacterial tooth paste consists of the following components in percentage by weight: 30-80% of a film-forming agent, 2-40% of a humectant, 0.2-2% of a thickening agent, 0.2-5% of a flavoring agent, 0.1-5.0% of an active medicine and 0.1-20.0% of an enzyme sensitive unit, according to the invention, a wrapping technology is innovatively introduced, effective components are wrapped in the sensitive unit with enzyme specific response, the sensitive unit has an intelligent response and active targeting mechanism, after the specific pathogenic bacterium characteristic enzyme is triggered, the drug is accurately released at the infected part, the frequency of drug use is lower, the side effect is smaller, the normal flora in the oral cavity is protected, and the safety is higher. According to the dental patch, the defect that a traditional dental patch releases drugs indiscriminately is overcome, intelligent response to a dental plaque biofilm is achieved, and the dental patch has wide application prospects in the aspect of precise prevention and treatment of periodontitis, caries and other oral diseases.

A nanoparticle composition for oral care includes at least one of a first set of spherical nanoparticles or a second set of coral shaped nanoparticles, and a stabilizing agent. The nanoparticle composition is added to a carrier suitable for application to an oral cavity, including to teeth and surrounding oral tissues. The nanoparticle composition can be a stable, 1-part composition. The nanoparticle composition is configured to control the pH of the microenvironment to which it is applied, thereby preventing and / or treating a variety of oral conditions. The nanoparticle composition can be provided as a concentrated nanoparticle additive addable to a mouthwash, mouth rinse, dentifrice, mouth spray, oral gel, denture cleaning solution, or other carrier suitable for oral application. The oral care composition is not a nasal spray.

The invention discloses an oral disease auxiliary evaluation system based on deep learning, which relates to the technical field of oral disease evaluation, and comprises a data preprocessing module, a feature extraction module, a model training and regularization module, a reinforcement learning strategy module and a diagnosis output and feedback module, oral cavity image data from different sources are collected and preprocessed, the data quality and diversity are improved, and the imbalance problem in original data is solved. Through multi-data-source integrated learning and a data enhancement strategy, the model can learn more features from diversified data, the deviation caused by data singleness and imbalance is reduced, and the adaptability to different devices, conditions and patients is improved. In combination with cross validation and an early stop mechanism, overfitting is effectively avoided, use of computing resources is optimized, and it is ensured that the training process is efficient and stable. According to the methods, the generalization ability and accuracy of the model are improved, so that the model is more reliable in actual clinic.

The utility model discloses an electric toothbrush with a standing base, which comprises an electric toothbrush rod and further comprises a butt joint type shaver assembly, the butt joint type shaver assembly comprises a body, an inner pipe is arranged on one side of the body, an insertion block is installed inside the inner pipe in an insertion connection mode, a shaver is arranged on one side of the insertion block, and a metal net is arranged on one side of the shaver. A user only needs to carry one product, the requirements of oral cavity cleaning and face shaving can be met at the same time, frequent switching among different tools is not needed, and the multifunctional cleaning tool is convenient and fast to use. Due to the advanced multifunctional cleaning technology and the intelligent design, the oral cavity and the face can be cleaned and nursed more effectively, oral diseases and skin problems are prevented, and the life quality of a user is improved. Due to the compact design and the waterproof performance, the product can be normally used in different environments and is convenient to carry, and the nursing requirements of a user in different scenes are met.