The utility model discloses a kind of classification storage anti-expiration medical material car of upper replenishment and lower taking, specifically related to medical instrument field.The utility model provides a kind of classification storage anti-expiration medical material car of upper replenishment and lower taking, including material car ontology, storage box, the material car ontology is equipped with storage cavity, the storage box is arranged in the storage cavity, and the storage box can be pulled out or retracted in the storage cavity, the storage box is equipped with multiple storage grids, the top of the storage grid is equipped with drop opening, the sidewall of the bottom of the storage grid is equipped with outlet, the outlet is equipped with baffle for closing the outlet, the baffle can be moved on the sidewall of the storage grid to open or close the outlet.