The invention relates to a high-
voltage power supply for medical plastic 
package liquid leakage detection and a detection method. The detection power supply comprises a sine-wave 
signal generating circuit, a power amplification circuit, a high-frequency 
transformer, a high-
voltage discharge circuit and a liquid leakage alarm detecting circuit, and is characterized in that an external 
DC voltage signal is accessed through an input end of the sine-wave 
signal generating circuit, a plastic 
package to be detected is placed in a high-
voltage discharge gap of the high-voltage 
discharge circuit, and the liquid leakage alarm detecting circuit externally outputs a liquid leakage 
alarm signal. Whether the plastic 
package leaks or not is detected by using a high-voltage discharge method, the high-voltage discharge circuit stays at different degrees of 
short circuit when the plastic package stays at different degrees of liquid leakage, high-voltage output has characteristics of a 
voltage source, high-voltage output voltage is relatively constant, and high-voltage output current changes obviously, so that the liquid leakage alarm detecting circuit is facilitated to give out a liquid leakage 
alarm signal accurately, and thus the reliability of liquid leakage detection can be improved.