The invention discloses an automatic PE glove folding machine which comprises a machine frame, a left station lifting material table, a right station lifting material table, a double-station vacuum material absorbing mechanism, a left-and-right turnover mechanism, a first-time folding mechanism, a second-time folding mechanism and a third-time folding mechanism. The left-and-right turnover mechanism is arranged in the middle of the top of the machine frame, the first-time folding mechanism, the second-time folding mechanism and the third-time folding mechanism are sequentially arranged on the machine frame from top to bottom, the left station lifting material table and the right station lifting material table are symmetrically arranged on the two sides of the left-and-right turnover mechanism, and the double-station vacuum material absorbing mechanism is arranged above the left-and-right turnover mechanism. The structural design is ingenious and reasonable, a PE glove can be rapidly folded, the folding effect is good, efficiency is high, the machine is controlled through a PLC, operation is convenient and rapid, the automation degree is high, the motion process is free of manual intervention, one person can operate multiple machines, cost is saved, production efficiency is greatly improved, and the machine has the obvious economical value and facilitates wide popularization and application.