The invention provides a nanometer bionic wound-
surface cover and a preparation method thereof. The nanometer bionic wound-
surface cover comprises a nanometer bionic bracket and
hydrosol attached to the bracket, wherein the
hydrosol covers one or a plurality of cytokines. The preparation method for the nanometer bionic wound-
surface cover provided by the invention comprises the steps of preparingan electrostatic-
spinning solution, a
cytokine-containing
hydrosol solution and a crosslinker solution, preparing the nanometer bionic bracket by use of electrostatic
spinning, using an ink-jet printer to print the
cytokine-containing hydrosol solution onto the nanometer bionic bracket, and the like, wherein electrostatic
spinning and printing can be repeated so as to form the wound-surface covers different in thickness. The preparation method adopts an in-situ autologous stem-
cell engineering technique and adopts stem-
cell chemotactic factors to attract autologous stem cells to directionally migrate, enter a
wound surface and be differentiated according to designed requirements, thereby avoiding inconvenience caused by using viable cells, achieving
rehabilitation effects the same with orbetter than that of using the viable cells and having broad application prospects.