The invention discloses an inner single-blade type capping method and an inner single-blade type capping mechanism, and relates to filling and sealing equipment in the technical fields of pharmaceutical machinery and food packaging machinery. The capping mechanism consists of a central shaft (14), a large rotary disc (17), a support disc (13), a cam (12), a pallet (6), a gearwheel (5), a roller (11), a roller guide base (10), a roller guide rod (9), a rolling cutter holder (8), a rolling cutter (7), a returning spring (16), a tension spring column (15), a gland head (3), a gland head transmission gear (4) and a bottle lifter component (1). The method and the mechanism have the characteristics of good capping effect, high efficiency, low energy consumption, small occupied space, good working environment and the like, canbe used for capping bottles such as oral liquid bottles, cillin bottles, large infusion bottles, wine bottles, drinking bottles and the like in the fields of pharmacy, foods and beverages and the like, and can also be used for capping glass bottles, plastic bottles or other bottles in various industries.