A method, system, and program product for recovering from a bus error in a computer system having a hot plug interface. In accordance with the method of the present invention, an operating system transparent interrupt, such as a system management interrupt, is generated in response to a bus error. Responsive to the operating system transparent interrupt, the hot pluggable bus is scanned and a device associated with the error is identified by an interrupt handler invoked by the interrupt. Finally, a hot plug configuration manager, such as an advanced configuration and power interface is utilized to remove the identified device from system operations without having to restart the system.