80 results about "Chronic failure" patented technology

The present invention provides one composite medicine for treating chronic heart failure. The composite medicine has the functions of invigorating vital energy, dredging meridian, promoting blood circulation and diuresis. The medicine composition has 11 kinds of Chinese medicinal materials including astragalus root or white atractylodes rhizome, mankshood, ginseng or Dangshen, red sage, pepperweed seed, etc. The pharmacological test shows that the capsule of the present invention has obvious improving effects to heart failure of dog caused by Pentobarbital sodium.

The invention discloses a traditional Chinese medicine for treating chronic renal failure and aims at solving the problems that the prior art supports the life by dialysis so as to result in short life cycle of patients and high cost and the like. The traditional Chinese medicine comprises the following raw materials: 30g of raidx astragali, 10g of white ginseng, 20g of rhizoma atractylodis macrocephalae, 20g of honey-fried licorice root, 20g of poria, 10g of Chinese angelica, 20g of rehmannia glutinosa, 20g of white paeony root, 10g of wrinkled gianthyssop herb, 15g of pinellia tuber and the like. The prescription is used for treating chronic uremia, can invigorate vigour, strengthening the spleen, replenishing blood, nourishing the blood, excreting water, expel toxin, strengthening the kidney and expel toxin, can reduce dialysis gradually by combining the modern medical method, finally separate the dialysis and transfusion, relieve economic burden of the patients, improve disease process fundamentally, improve life quality and courage and prolong life cycle.

The present invention aims to provide a therapeutic agent for chronic renal failure, comprising as an effective ingredient a compound represented by General Formula (1) or a pharmaceutically acceptable salt thereof. That is, the present invention provides provision of a drug comprising as an effective ingredient a compound represented by General Formula (1) or a pharmaceutically acceptable salt thereof, which drug is useful not only for amelioration of renal function, but also for amelioration of anemia, activation of SOD and excretion of uremic substances.

The invention relates to a traditional Chinese medicine for treating chronic renal failure. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 30 parts of asiatic centella, 10 parts of caulis bambusae in taenian, 30 parts of astragali radix, 12 parts of dodder, 25 parts of serissa serissoide, 15 parts of silkworm excrement, 15 parts of Dangshen and 9 parts of tuber pinellia. Clinic experiments prove that the traditional Chinese medicine can be used for safely and effectively treating the chronic renal failure.

The invention relates to a medicine for curing chronic renal failure and a production method thereof, which is characterized in that the medicine is calcium-base samoite excluding K+, Na+, Mg2+ and other exchangeable cations. The preparation method includes immersing the samoite in calcium chloride solution and then exchanging ions. After oral administration, toxins in the alimentary tract of patients with chronic renal failure is absorbed by samoite of the medicine and then discharged out of the body along with intestinal peristalsis, thus achieving intestinal hemodialysis. While absorbing and fixing the toxins in the alimentary tract, the calcium-base samoite has no side effect on patients of Na and K restriction without releasing K+, Na+, Mg2+ and other exchangeable cations.

The invention relates to a Chinese medicinal formula for treating chronic renal failure. The formula consists of the following raw materials by weight (counted by gram): 12-16g of roasted aconite (decocted firstly), 12-16g of south dodder seed, 15-22g of cortex eucommiae, 15-22g of astragalus, 15-22g of dangshen, 15-22g of indian buead, 12-18g of large-head atractylodes rhizome, 15-22g of Chinese yam, 12-18g of pokeberry root, 12-16g of areca peel, 15-22g of umbellate pore fungus, 20-30g of rhubarb, 25-32g of red-rooted salvia root, 25-32g of honeysuckle flower, 25-32g of dandelion and 15-22g of sweet basil. After being taken by a patient suffering from chronic renal failure, a medicament prepared in the weight ratio has the effects of exciting potential, improving physique, improving symptoms, promoting the excretion of metabolic waste, relieving the state of an illness and prolonging life.

The invention discloses a preparation method of a chronic renal failure colon dialysate for solving the treatment problem of chronic renal failure. The preparation method is characterized in that the preparation method comprises the following steps of: (1) performing reduced pressure distillation on ailanthus-like pricklyash bark, catclaw buttercup root and Chinese ephedra root coarse powder to extract volatile oil; (2) performing reduced pressure decoction on tall gastrodia tuber to obtain a filtrate; (3) performing water decoction on trikeraia hookeri, magnolia amoena, dragon's blood, melanoidin malt, scorch-fried medicated leaven, mimoselike rosewood leaf, peach gum, cassia twig and dregs obtained in the step (1) to obtain a filtrate for later use; (4) merging the filtrates obtained in the steps (2) and (3), performing reduced pressure concentration to obtain a dry extract, and crushing to obtain dry extract powder; (5) spraying the volatile oil obtained in the step (1) into the dry extract powder obtained in the step (4), uniformly mixing, and screening by a 100-mesh screen to obtain colon dialysis concentrated powder; and (6) adding ten times the volume of warm water into the colon dialysis concentrated powder obtained in the step (5) during the use, and uniformly mixing. Clinical experiments prove that by using the chronic renal failure colon dialysate for treating the chronic renal failure, the frequency of hemodialysis can be reduced, and the preparation method is further worthy of clinical application and popularization.

The invention relates to a drug composition for treating chronic heart failure. The drug composition is prepared from the crude drugs of traditional Chinese medicines such as ginseng, monkshood (fried), astragalus mongholicus, radix ophiopogonis, root of red-rooted salvia, rhizoma alismatis, tuckahoe, plantain herb and the like. The drug composition has the effects of warming yang and reinforcing qi, promoting blood circulation and excreting pathogenic water, and is clinically used for treating the chronic heart failure.

The invention relates to a marine collagen peptide and the application thereof in the preparation of medicine, health food or food used for the protection of renal function and slowing the progress of chronic renal failure. Marine collagen peptide is a group of low-molecular weight oligopeptide mixture generated through the hydrolysis of fish skins of marine fish (salmon, chinook salmon, tilapia and the like). The molecular weight of 70%-80% of oligopeptide is distributed between 200-1000Da. The marine collagen peptide has the advantages of easy absorption, fast absorption, low viscosity, good water-solubility. The experiments prove that the marine collagen peptide can have the efficacy of slowing the adenine-induced chronic renal function impairment of rats.

The invention discloses a clysis liquid used for chronic renal failure, solving the problem of the treatment of chronic renal failure. The clysis liquid is prepared from the following raw medicines: erythrina indica lam, trikeraia hookeri, tetrapanax papyriferum, magnolia amoena, sangusis draconis, radix ranunculi ternate, caramel malt, medicated leaven, mussel, folium dalbergiae mimosoidis, prunus persica (L.) batsch and cassia twig. The clinical experiment result shows that the clysis liquid has the characteristics of high curative effect and relatively high safety on chronic renal failure treatment, and is worthy for clinical application and popularization.

The invention discloses a traditional Chinese medicine combination for treating chronic renal failure. The traditional Chinese medicine combination is prepared from the following raw materials: 30-45 parts of codonopsis pilosula, 30-60 parts of tuckahoe, 30-120 parts of atractylodes, 30-45 parts of baked licorice, 30-60 parts of raw radix astragalis, 15-60 parts of rhizoma alismatis, 10-15 parts of agastache, 5-20 parts of wine-treated rhubarb, 10-15 parts of amomum fruits, 10-15 parts of schisandra chinensis, 10-30 parts of sliced processed aconite, 45-75 parts of cassia twig, 10-30 parts of Chinese angelica, 10-15 parts of cinnamon and 30-60 parts of semen coicis. The traditional Chinese medicine combination is prepared into internal preparations according to conventional accessories and technologies in pharmaceutical fields. The traditional Chinese medicine combination has the advantages that the traditional Chinese medicine combination is prepared by pure traditional Chinese medicine raw materials, rigorous in compatibility and dialectic in legislation. When the traditional Chinese medicine combination suits the case, azotemia can be effectively treated, serum creatinine and urea nitrogen can be remarkably reduced, and renal failure conditions are obviously relieved and delayed.

The invention discloses an early warning system for a chronic renal failure, and belongs to the field of medical detection. The early warning system for the chronic renal failure comprises a data acquisition unit used for collecting the urine volume, urine creatinine and serum creatinine of a patient to generate detection values, a calculation unit used for calculating creatinine clearance rates according to the detection values, a prediction unit used for establishing a Markov-grey model, and calculating predicted values of the creatinine clearance rates in future time periods according to the N creatinine clearance rates calculated through the detection values of N detection time periods, wherein N is an integer greater than 3, and an early warning decision unit used for determining the early warning level of the chronic renal failure according to the predicted values of the creatinine clearance rates. According to the invention, modeling analysis is carried out on the creatinine clearance rates to predict the probability that a kidney has the chronic renal failure and timely discover non-overt renal injuries in early kidney asymptomatic lesions so as to provide effective help in clinical early confirmed diagnosis and later treatment.

The invention relates to a Chinese medicament for treating chronic kidney failure, and belongs to the field of Chinese medicaments for treating urinary system diseases. The invention aims to provide the Chinese medicament with good effect and quick response. The Chinese medicament is prepared from the following raw materials: anemarrhena asphodeloides bunge, lucid ganoderma, common curculigo rhizome, prepared rhubarb, root of rehmannia, Chinese angelica, epimedium herb, radix pseudo-ginseng, oyster and the like. The Chinese medicament has the effects of strengthening body resistance and banking up root, tonifying qi and nourishing blood, activating blood and dissolving stasis, and tonifying and warming kidney Yang, and has the advantages of obvious effect, exact medicinal effect and quick response.

The invention relates to a pharmaceutical composition comprising an angiotensin converting enzyme inhibitor (ACEI), an enkephalinase inhibitor, a folic acid compound and a pharmaceutically acceptable carrier, wherein the ACEI is selected from the group consisting of enalapril, benazepril, ramipril, fosinopril, cilazapril, perindopril and the like, and the content is 1.25-75 mg; the enkephalinase inhibitor is sacubitril, and the content is 10-120 mg; and the folic acid compound is selected from the group consisting of folic acid, 5-methyltetrahydrofolate, calcium formyltetrahydrofolate, leucovorin, calcium levofolinate and the like, and the content is 0.1-5 mg. The invention provides the use of the pharmaceutical composition in the preparation of a medicament for the treatment of chronic heart failure and the prevention of stroke. By the implementation of the invention, the pharmaceutical composition can also improve the compliance of patients and improve the therapeutic effect by providing the pharmaceutical composition for a specific use to the patients.

A Chinese medicine for treating chronic renal failure is prepared from more than 10 Chinese- medicinal materials including astragalus root, notoginseng, epimedium, ground beetle, etc.

The invention discloses a traditional Chinese medicine composition for treating chronic renal failure. The traditional Chinese medicine composition for treating chronic renal failure is prepared from, by weight, 3-8 parts of Folium Perillae, 5-12 parts of Fructus Mume, 12-17 parts of Folium Ginkgo, 4-6 parts of Semen Cuscutae, 8-12 parts of Radix Saposhnikoviae, 3-4 parts of Radix Sacchari Arundinacei, 12-15 parts of Fructus Rosae Multiflorae, 5-9 parts of Radix Cynanchi Paniculati, 3-4 parts of Herba Ziziphorae Clinopodioidis, 5-8 parts of Spica Prunellae, 12-15 parts of Radix Polygoni Multiflori, 10-16 parts of Radix Stellariae Yunnanensis, 7-12 parts of Herba Taraxaci, 4-9 parts of Herba Scutellariae Barbatae, 15-20 parts of Rhizoma Curculiginis, 10-15 parts of Herba Hedyotidis Diffusae, 8-12 parts of Radix Rubiae, 2-5 parts of Fructus Akebiae Quinatae, 3-7 parts of Herba Centellae, 11-14 parts of Flos Lonicerae, 9-15 parts of Radix Notoginseng, 3-6 parts of Herba Cistanche, 8-13 parts of Flos Campsis, 3-5 parts of Rhizoma Sparganii, 1-3 parts of Fructus Gardeniae, 5-10 parts of Herba Aleuritopteris Argentea, 5-10 parts of Medulla Junci, 13-16 parts of Herba Leonuri, 3-10 parts of Radix et Rhizoma Iridis Sanguineae and 8-13 parts of Rhizoma Pinelliae.