The invention discloses a multi-sensory training system based on a 3D printing technology. The system comprises a control host, a 3D printing training module, an interaction experience module, a 3D sand painting designing module and a work displaying module, wherein the 3D printing training module, the interaction experience module, the 3D sand painting designing module and the work displaying module are respectively connected with the control host; several 3D printing devices are arranged on the 3D printing training module; the interaction experience module is provided with several multi-sensory training devices used for vision, hearing, smell, taste and touch training; the 3D sand painting designing module is provided with a sand painting platform, a projector and a multi-functional displaying screen; the work displaying module is provided with several tablet computers I. Through a comprehensive rehabilitation training system based on the 3D printing technology, children sufferingfrom cerebral palsy and infantile autism are helped to get rid of troubles of social communication disorder, speech development disorder, communication ability defect and other disorders, potential development and improved adaptive ability are achieved, the understanding and the thinking ability are improved, and therefore the social identity sense and social living ability of the children are further improved.