Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

40 results about "Crystal cluster" patented technology

A crystal cluster is a group of crystals which formed in an open space environment and exhibit euhedral crystal form determined by their internal crystal structure. A cluster of small crystals coating the walls of a cavity are called druse.

Steel plate HT690 capable of being subjected to high heat input welding and manufacturing method thereof

The invention relates to an HT690 steel plate capable of being subjected to high heat inputwelding and a manufacturing method thereof. A component system treated by low C-high Mn-(Nb+V+B) microalloying-ultramicro Ti is adopted, the acid-soluble Als content in steel is properly improved, the Als is not less than (Mn equivalent / C)*(Ntotal-0.292Ti), (Mn equivalent) / C is between 20 and 40, Pcm is not more than 0.205 percent, the Ti / N is between 2.0 and 4.0, (Cu+Ni+Mo+Cr) is alloyed and Ni / Cu is not less than 1.0, the Ca is treated and the Ca / S ratio is between 0.80 and 3.00 and the F*DI index is controlled to be not less than 0.80*finished steel plate thickness, a TMCP (Thermo-Mechanical Control Process) and a tempering process are optimized to ensure that the microscopic structure of a finished steel plate is fine tempering bainite, and the average crystal cluster size is below 25mum. The steel plate can bear high heat input welding at the same time of obtaining the properties of uniform and excellent obdurability and strong plasticity matching, is especially suitable for large steel structures of a hydroelectric pressure water pipe, a vortex, a sea platform and the like, and can realize low-cost and stable batch industrialized production.
Owner:BAOSHAN IRON & STEEL CO LTD

Microcrystalline glass with nanocrystal clusters distributed in glass phase, and preparation method thereof

The invention relates to a microcrystalline glass with nanocrystal clusters distributed in the glass phase, and a preparation method thereof. The microcrystalline glass contains 35-65wt% of SiO2, 10-30wt% of CaO, 3-15wt% of Al2O3, 3-15wt% of MgO, 0-5wt% of Na2O, 0-5wt% of K2O, 2-5wt% of B2O3, 1-8wt% of CaF2, 5-15wt% of Fe2O3, 0.01-5wt% of Cr2O3 and 0.1-8wt% of REO. Rare earth oxide (REO) is added to make crystal clusters formed in the glass phase in order to improve the mechanical performances of the microcrystalline glass. The microcrystalline glass prepared through the method has the advantages of low production cost, simple preparation method, wide application range and good mechanical performances.
Owner:INNER MONGOLIA UNIV OF SCI & TECH

Stable nanomagnetic particle dispersions

Processes and compositions are described for preparing new, colloidally stable, coated nanomagnetic particles useful for both in-vitro and in-vivo biomedical applications, including cell targeting and capturing cells, microorganisms, and cellular organelles or entities such as exosomes. These nanomagnetic particles can also be used as imaging contrast agents due to their small size and high magnetic moment. The nanomagnetic particles include a series of sequentially added, stabilizing surface coatings rendered onto nano-sized magnetic crystal clusters (e.g., magnetite particles) to impart colloidal stability in complex biological samples with minimal leaching of the coating materials, high binding capacity, and low non-specific binding. Another benefit of this invention is the ability to utilize both external and internal magnetic field-generating separation devices to effect separation of the magnetic nanoparticles.
Owner:BIOLEGEND INC

Method for preparing protein ribonuclease modified copper sulfide nanometer material

The invention discloses a method for preparing protein ribonuclease modified copper sulfide nanometer material. The method includes: firstly, preparing chelated solution, and crosslinking amino acid groups of protein crystals of protein ribonuclease with semiconductor metal ions; secondly, adding a sulfur source, using protein crystal clusters as a framework, combining excessive copper and sulfur ions in a reaction system with driving copper sulfide nano particles to growth continuously, and controlling reaction time and reactant concentration to obtain a spherical nano structure. The copper sulfide spherical nano structure significantly promotes specialties of multiple disciplinaries such as photovoltaic conversion, photocatalysis, drug controlled-release and gene carriers. The method is simple in operation, mild in condition, low in cost and environment-friendly, the synthesized product copper sulfide nano balls have water solubility and stability and high biocompatibility, and the method is a simple method for preparing functional nano materials.
Owner:SHANGHAI JIAO TONG UNIV

Method for manufacturing silver sulfide hollow sphere modified by protein ribonuclease

The invention discloses a method for manufacturing a silver sulfide hollow sphere modified by protein ribonuclease. The method provided by the invention comprises the following steps: firstly preparing chelate solution, using amino acid perssad of protein ribonuclease protein crystal to be combined with semiconductor metal ion in a cross-linking way, adding sulphur resources in the chelate solution, and taking a protein crystal cluster as a framework to manufacture a nanostructured hollow sphere by utilizing the combination of excess silver ions and sulphur ions in a reaction system to drive silver sulfide nano-particles to grow constantly and control the time of reaction and the concentration of reactant. The nanostructured hollow sphere provided by the invention has significant facilitation for multiple disciplines such as photoelectricity conversion, photochemical catalysis, drug sustained release, gene carrier and the like. According to the invention, the method is simple to operate, needs warm condition, has low cost and has no pollution; the synthesized silver sulfide nano hollow sphere has good water-solubility, stability and biocompatibility, so that the method is a simple method to manufacture a functional nano-material; and the manufactured nono-material has a special structure, so that the method provided by the invention has great market application value.
Owner:SHANGHAI JIAO TONG UNIV

Stable nanomagnetic particle dispersions

Processes and compositions are described for preparing new, colloidally stable, coated nanomagnetic particles useful for both in-vitro and in-vivo biomedical applications, including cell targeting and capturing cells, microorganisms, and cellular organelles or entities such as exosomes. These nanomagnetic particles can also be used as imaging contrast agents due to their small size and high magnetic moment. The nanomagnetic particles include a series of sequentially added, stabilizing surface coatings rendered onto nano-sized magnetic crystal clusters (e.g., magnetite particles) to impart colloidal stability in complex biological samples with minimal leaching of the coating materials, high binding capacity, and low non-specific binding. Another benefit of this invention is the ability to utilize both external and internal magnetic field-generating separation devices to effect separation of the magnetic nanoparticles.
Owner:BIOLEGEND INC

Device for crystal growth at intermediate temperatures using controlled semi-active cooling

A crystal growing cell which has computerized temperature control and agitation means to inhibit crystal nucleation. The temperature is controlled semi-actively, i.e., by monitoring the temperature with a thermistor and balancing ambient heat loss with heat added to the system by heating resistors or heating elements. When the chemical is completely dissolved by heating the mixture to a temperature above the saturation temperature, the temperature is lowered. At the saturation temperature the temperature is initially reduced slowly to avoid crystal nucleation. The saturation temperature of the initial solution is selected to be at an intermediate temperature which is high enough that the amount of dissolved material is large enough to produce a large crystal or large crystal clusters, yet not so high that the solubility curve has a large slope and therefore requires a high degree of temperature control to avoid crystal nucleation in the solution. Use of the cell with a variety of chemical solutions, each having the same saturation temperature, facilitates optimization while maintaining a simple, low cost design.
Owner:KRAUTTER MICHAEL

A Ni-Co lithium manganate cathode material and a preparation method thereof

ActiveCN108987741AGuaranteed compaction densityAchieve high rate capacityCell electrodesSecondary cellsHigh rateCharge discharge
A Ni-Co lithium manganate material is disclosed. The Ni-Co lithium manganate is prepare by taking lanthanum nickel oxide nanocrystal as heterogeneous crystalline core, A layer of lithium nickel cobaltmanganate grain is attached to that lanthanum nickel oxide nanocrystal, forming a lithium nickel cobalt manganate micron crystal cluster powder with lanthanum nickelate as the core, the problems of poor high rate capacity performance and poor cycle stability of the existing ternary material lithium batteries are solved, The preparation method of the invention provides a crystalline core of the lithium nickel cobalt manganate through a preset nanocrystalline core, forms lithium nickel cobalt manganate cluster particles with a lanthanum nickel oxide skeleton, provides an internal conductive channel, is conducive to improving and exerting the charge-discharge specific capacity of the lithium nickel cobalt manganate ternary battery, and is simple and feasible.
Owner:XIAN UNIV OF TECH

Medicine-loaded medical instrument and preparation method thereof

The invention relates to the technical field of medicines, in particular to a medicine-loaded medical instrument. The medicine-loaded medical instrument comprises a medical instrument body and at least one medicine coating, wherein the medicine coating is attached to at least one side of the surface of the medical instrument body, and the main components of the medicine coating comprise macrolidemedicines. The medicine coating comprises a long cylindrical crystal with three or more edges, and / or the medicine coating comprises a crystal cluster formed by the long cylindrical crystal with threeor more edges, and the length-diameter ratio of the long cylindrical crystal is (1-40): 1. The medicine-loaded medical instrument can effectively improve the transfer of medicines to a vascular walland prolong the concentration the tissue medicines.
Owner:SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD

Pressable glass-ceramics with textured microstructure

A pressable dental ceramic comprising a mixture of glass and glass-ceramic frits. A refractory filler is also combined with the frits. The dental ceramic contains an amount of leucite less than about 35 percent by weight. Other additives may be included such as pigments, opacifying agents and fluorescing agents. The dental ceramic comprises a cellular-like microstructure comprised of glassy regions surrounded by clusters of leucite crystals distributed around those glassy regions forming a cellular three-dimensional network.
Owner:ARDENT

Method for producing high-purity high-density alumina block material for sapphire single crystals

The invention discloses a method for producing a high-purity high-density alumina block material for sapphire single crystals. A high-frequency induction power supply is utilized as a heating power supply, an alumina micropowder raw material in a cold crucible is melted to form a molten bath, and a Bruceton-process single crystal growing process making the cold crucible slowly reduced is combined, so that alumina in the molten bath generates multi-nucleus directional crystallization, and fine columnar or needle-like alumina smallcrystal clusters are obtained finally. The method is used for producing the high-purity high-density alumina block raw material, has low unit electricity consumption and is easy for mass production; and the obtained alumina smallcrystals have the purity of over 99.997 percent, the volume density of not less than 3.7g / cm<3> and the bulk density of not less than 2.0g / cm<3>.
Owner:李振亚 +1

Preparation method of isobutyl cage type polysilsesquioxane modified polyurethane

The invention discloses a preparation method of isobutyl cage polysilsesquioxane modified polyurethane. First, the isobutyl cage polysilsesquioxane is pretreated in a vacuum oven, and then mixed with xylene Diisocyanate is reacted to prepare prepolymer, and then polyether polyol VORANOL 3010 is added for chain extension reaction, and modified by chemical bonding to prepare nano-organic-inorganic hybrid modified polyurethane. When the content of isobutyl cage polysilsesquioxane increased from 0% to 22%, the glass transition temperature of the modified polyurethane increased from ‑44.3 to ‑13.9°C, an increase of 30.4°C. The mechanical properties have been significantly improved. At the same time, with the increase of isobutyl cage polysilsesquioxane content, some sharp diffraction peaks appeared in the X-ray diffraction pattern of the modified polyurethane. Compared with the X-ray diffraction patterns of pure polyurethane, it can be concluded that the increase of the content of isobutyl cage polysilsesquioxane promotes the formation of crystal clusters and the obvious hard segment-soft segment microphase separation in the modified polyurethane structure Phenomenon, to a certain extent, improve the shaping of modified polyurethane.
Owner:SICHUAN NORMAL UNIVERSITY

Nanometer particle containing elemental gold and application thereof

The invention relate to a nanometer particle containing elemental gold. The nanometer particle is characterized by comprising nanometer crystal clusters formed by the elemental gold. The elemental gold has the 2[theta] measuring feature peak mainly at 38.2 degrees in an X-ray powder diffraction spectrum, and 2[theta] measuring feature peaks at 44.3 degrees, 64.7 degrees, 77.7 degrees, 82.0 degrees and the like. The nanometer particle provided by the invention belongs to the nanometer particle below 100nm; in addition, the particle diameter distribution is narrow; the nanometer particle realizes the long-period stable suspension in a solution state without sedimentation for at least one month (partial samples realize the stable state maintaining for 12 months); and the nanometer particle is suitable to be used for in vivo X-ray or CT (Computed Tomography) imaging detection as a contrast agent.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Constant current diffused protein crystallization method, open type constant current diffused protein crystallization array chip and manufacture method and application of chip

The invention relates to a constant current diffused protein crystallization method, an open type constant current diffused protein crystallization array chip and a manufacture method and application of the chip. The open type constant current diffused protein crystallization array chip comprises a base and a substrate fixed on the base, wherein a plurality of hole-shaped protein crystallization units communicated with the external environment are distributed on the substrate so as to form a crystallization unit array, a plurality of microflow main channels are also distributed on the substrate, and each crystallization unit is communicated with a corresponding microflow main channel through radial microflow diffused channels. Protein solution is injected into the microflow main channels in a constant current manner, and precipitator solution in the open type crystallization units is static. The open type constant current diffused protein crystallization array chip has the advantages that 1. a high protein concentration gradient is maintained between the microflow main channel and the crystallization units, so that the protein molecules are continuously diffused into the crystallization units, the protein is crystallized rapidly, and the crystal cluster has high density; 2. the protein crystals formed in the crystallization units are free from the influence of the shear force and can be conveniently extracted and analyzed; 3. the consumption of the protein is small, the operation is flexible, and the method is suitable for high-pass screening under crystallization condition; and 4. the chip is simple to manufacture, has a compact structure, is low in cost and can be produced in a large scale.
Owner:武汉介观生物科技有限责任公司

Method for synthesizing CoAPO-41 molecular sieve

The invention discloses a method for synthesizing a CoAPO-41 molecular sieve and relates to a method for synthesizing a molecular sieve. The invention aims at solving the problems that relatively high acid site density cannot be formed without introducing a large quantity of Si atoms in the existing synthesis process of an SAPO-41 molecular sieve, but the Si atoms hardly enter the molecular sieve framework and are uniformly distributed on the framework to form a non-framework amorphous species which deposits in the pore orifices or pore channels of the molecular sieve to cause partial blocking of the pore orifices or pore channels. The method comprises the following steps: (I) preparing initial gel; and (II) crystallizing and roasting to obtain the CoAPO-41 molecular sieve. In the invention, the prepared CoAPO-41 molecular sieve is a spherical aggregate or crystal cluster consisting of nano rods, wherein the crystallizing time is only (1 / 2)-(1 / 3) of that of the prior art while mixed crystals are avoided; and the CoAPO-41 molecular sieve can be applied to the fields such as petrochemical industry as an environment-friendly acid catalyst.
Owner:HEILONGJIANG UNIV

Method for preparing protein ribonuclease protein crystal modified lead sulfide nanorod

The invention discloses a method for preparing a protein ribonuclease protein crystal modified lead sulfide nanorod. The method includes preparing chelation liquor at first; leading amino acid perssad in protein ribonuclease protein crystal to be in cross-linking bonding with semiconductor metal ions; adding a sulfur source; and using a protein crystal cluster as a framework, bonding free lead in a reaction system with sulfur ions so as to drive lead sulfide nano particles to continuously grow, and controlling the reaction temperature and time and the concentration of reactant so as to prepare the nanorod structure. A lead sulfide ball nano structure has an important effect for promoting various subjects and professions including photoelectric conversion, photocatalysis, slow release of medicine, gene vectors and the like. The method has the advantages of simplicity in operation, mild condition, low cost and environmental protection, the synthetic lead sulfide nanorod is water-soluble and stable and is fine in biocompatibility, and the method is a simple method for preparing functional nano materials.
Owner:SHANGHAI JIAO TONG UNIV

Micro-rough electrolytic copper foil and copper foil substrate

The invention discloses a micro-rough electrolytic copper foil and a copper foil substrate. The micro-rough electrolytic copper foil comprises a micro-rough surface. The micro-rough surface is provided with a plurality of convex edges, a plurality of grooves and a plurality of micro-crystal clusters. The groove has a U-shaped section profile and / or a V-shaped section profile, the average width ofthe grooves ranges from 0.1 micrometer to 4 micrometers, and the average depth of the grooves is smaller than or equal to 1.5 micrometers. The micro-crystal clusters are positioned at the tops of theconvex edges. Each micro-crystal cluster is composed of a plurality of micro-crystal stacks with the average diameter smaller than or equal to 0.5 micrometer. The Rlr value of the micro-rough surfaceof the micro-rough electrolytic copper foil is lower than 1.3. Good bonding force exists between the micro-rough surface and the base material, good intervention loss is shown, and signal loss can beeffectively restrained.
Owner:CO TECH DEV CORP

Method for preventing sodium gluconate wet crystals from caking in drying process

The invention discloses a method for preventing sodium gluconate wet crystals from caking in the drying process and hardening during the storage period. Based on an existing drying process of a vibrated fluidized bed for the sodium gluconate wet crystals, a pneumatic conveying and feeding method is used for replacing an original vibration feeder, and the temperature and wind speed of the air flow for drying are regulated in a segmentation mode, so that the sodium gluconate wet crystals after centrifugal separation have better dispersity when entering the fluidized bed. The drying temperature after the sodium gluconate wet crystals enter the fluidized bed is controlled in a segmentation mode, so that the problems that the sodium gluconate wet crystals cluster and cake in the drying process and get damp and harden during the storage period are effectively prevented. The method for preventing sodium gluconate wet crystals from caking in the drying process and hardening during the storage period largely improves the pass rate of dried products, and guarantees the stability of the quality of products.
Owner:SHANDONG FOOD & FERMENT IND RES & DESIGN INST

Steel plate HT690 capable of being subjected to high heat input welding and manufacturing method thereof

The invention relates to an HT690 steel plate capable of being subjected to high heat inputwelding and a manufacturing method thereof. A component system treated by low C-high Mn-(Nb+V+B) microalloying-ultramicro Ti is adopted, the acid-soluble Als content in steel is properly improved, the Als is not less than (Mn equivalent / C)*(Ntotal-0.292Ti), (Mn equivalent) / C is between 20 and 40, Pcm is notmore than 0.205 percent, the Ti / N is between 2.0 and 4.0, (Cu+Ni+Mo+Cr) is alloyed and Ni / Cu is not less than 1.0, the Ca is treated and the Ca / S ratio is between 0.80 and 3.00 and the F*DI index is controlled to be not less than 0.80*finished steel plate thickness, a TMCP (Thermo-Mechanical Control Process) and a tempering process are optimized to ensure that the microscopic structure of a finished steel plate is fine tempering bainite, and the average crystal cluster size is below 25mum. The steel plate can bear high heat input welding at the same time of obtaining the properties of uniformand excellent obdurability and strong plasticity matching, is especially suitable for large steel structures of a hydroelectric pressure water pipe, a vortex, a sea platform and the like, and can realize low-cost and stable batch industrialized production.
Owner:BAOSHAN IRON & STEEL CO LTD

Seeded mesophase pitch process

Producing mesophase pitch from liquid hydrocarbon feed comprising multi-ring aromatic compounds. In a first stage reactor feed is converted to isotropic pitch product contaminated with mesophase pitch. Contaminated isotropic pitch is charged to a second stage reactor where mesophase formation by self-assembly into spherical crystal clusters produces a mesophase pitch product. Water or steam added to the first stage reactor increases conversion of aromatic liquid feed, increases mesophase contamination of isotropic pitch product and reduces coke formation in the isotropic pitch reactor.
Owner:ACP TECH LLC

Crystal cluster type inorganic binding agent and preparation method thereof

InactiveCN112659000AThe number of tiny nucleiNumber of small nucleiGlass furnace apparatusAbrasion apparatusMolten stateSmelting process
The invention discloses a crystal cluster type inorganic binding agent and a preparation method thereof. The crystal cluster type inorganic binding agent is prepared from the following components in percentage by weight: 20-60wt% of SiO2, 5-23wt% of Al2O3, 5-15wt% of B2O3, 1-5wt% of K2O, 1-8wt% of Li2O, 0-8wt% of Na2O, 1-4wt% of ZnO, 0-5wt% of BaO, 0-5wt% of MgO and 1-7wt% of a crystal cluster nucleating agent. In the smelting process, molten materials are nucleated under the supercooling condition that smelting is conducted at the high temperature, then rapid cooling is conducted to the relatively low temperature, heat preservation is conducted for a period of time, and then water quenching is conducted, a large number of tiny nucleation points are formed, silicate oxyanion groups are deposited and stacked on the nucleation points in combination with the sintering process of stepped heating, and a crystal cluster structure similar to a complexing type is formed, so that the glass ceramics are reinforced and toughened.
Owner:CHINA NONFERROUS METAL (GUILIN) GEOLOGY & MINING CO LTD

Asymmetric photonic crystal film capable of changing colors along with angles as well as preparation method and application of asymmetric photonic crystal film

ActiveCN114063200ARegulatory asymmetryComplex Optical Variation BehaviorOptical elementsPhotonic crystalMaterials science
The invention relates to the technical field of preparation of optical anti-counterfeiting materials, in particular to an asymmetric photonic crystal film capable of changing colors along with angles as well as preparation method and application of the asymmetric photonic crystal film. The photonic crystal film comprises a top layer film and a bottom layer film which are connected, and photonic crystals embedded in the top layer film and the bottom layer film respectively; the photonic crystal is of a 1D chain-shaped structure formed by superparamagnetic nano crystal cluster particles, and the 1D chain-shaped photonic crystal in the top layer film is obliquely oriented relative to the film surface; and the 1D chain-shaped photonic crystal in the bottom layer film is oriented perpendicular to the film surface. According to the asymmetric photonic crystal film capable of changing colors along with the angles, the asymmetry of the color changing along with the angle can be regulated and controlled by changing the inclination angle between the 1D chain-shaped photonic crystal in the top layer film and the film surface, and compared with a traditional photonic crystal anti-counterfeit label, the asymmetric photonic crystal film shows more complex optical change behaviors and higher imitation difficulty; and the anti-counterfeiting capability can be obviously improved.
Owner:WUHAN UNIV OF TECH

Explosive detection method based on colorimetric array technology

The invention relates to an explosive detection method based on a colorimetric array technology, and a detector involved in the method is composed of a sampling module, an image acquisition module, an ARM board card, an FPGA board card, a liquid crystal display module, a lithium battery and a power switch.According to the method, an area causing turbulent flow is designed in a sampling cavity; the airflow carrying the crystal cluster particles can be kept in the cavity for a longer time, and finally, the micro-nano colorimetric sensing chip has a good effect of collecting the floating explosive crystal cluster particles, and the micro-nano colorimetric sensing chip integrates a plurality of independent areas based on a colorimetric array technology and has the capability of carrying out specific color reaction with floating explosive crystal cluster particles; the method has the characteristic of intelligently and chemically analyzing the types of various standard and non-standard explosives, can accurately report the names, components and the like of the explosives or the easy-to-explode raw materials, covers the explosives and the easy-to-explode raw materials in the detection range, and achieves trace detection of the explosives and the easy-to-explode raw materials.
Owner:XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI

Glass-ceramic with nanocrystal clusters distributed in glass phase and method for preparing same

The invention relates to a microcrystalline glass with nanocrystal clusters distributed in the glass phase, and a preparation method thereof. The microcrystalline glass contains 35-65wt% of SiO2, 10-30wt% of CaO, 3-15wt% of Al2O3, 3-15wt% of MgO, 0-5wt% of Na2O, 0-5wt% of K2O, 2-5wt% of B2O3, 1-8wt% of CaF2, 5-15wt% of Fe2O3, 0.01-5wt% of Cr2O3 and 0.1-8wt% of REO. Rare earth oxide (REO) is added to make crystal clusters formed in the glass phase in order to improve the mechanical performances of the microcrystalline glass. The microcrystalline glass prepared through the method has the advantages of low production cost, simple preparation method, wide application range and good mechanical performances.
Owner:INNER MONGOLIA UNIV OF SCI & TECH

Method for manufacturing silver sulfide hollow sphere modified by protein ribonuclease

The invention discloses a method for manufacturing a silver sulfide hollow sphere modified by protein ribonuclease. The method provided by the invention comprises the following steps: firstly preparing chelate solution, using amino acid perssad of protein ribonuclease protein crystal to be combined with semiconductor metal ion in a cross-linking way, adding sulphur resources in the chelate solution, and taking a protein crystal cluster as a framework to manufacture a nanostructured hollow sphere by utilizing the combination of excess silver ions and sulphur ions in a reaction system to drive silver sulfide nano-particles to grow constantly and control the time of reaction and the concentration of reactant. The nanostructured hollow sphere provided by the invention has significant facilitation for multiple disciplines such as photoelectricity conversion, photochemical catalysis, drug sustained release, gene carrier and the like. According to the invention, the method is simple to operate, needs warm condition, has low cost and has no pollution; the synthesized silver sulfide nano hollow sphere has good water-solubility, stability and biocompatibility, so that the method is a simple method to manufacture a functional nano-material; and the manufactured nono-material has a special structure, so that the method provided by the invention has great market application value.
Owner:SHANGHAI JIAO TONG UNIV

Constant current diffusion protein crystallization method and open constant current diffusion protein crystallization array chip and its fabrication method and application

The invention relates to a protein crystallization method based on constant current diffusion, an open constant current diffusion protein crystallization array chip and a manufacturing method and application thereof. The open constant current diffusion protein crystallization array chip includes a substrate and a substrate fixed on the substrate; several hole-shaped protein crystallization units communicating with the external environment are distributed on the substrate to form an array of crystallization units; Several microfluidic main channels are distributed; each crystallization single-pass radial microfluidic diffusion channel communicates with the corresponding microfluidic main channel. The protein solution was injected into the microfluidic main channel in a constant flow, while the precipitant solution in the open crystallization unit was static. The advantages of the present invention are: 1. A high protein concentration gradient is maintained between the microfluidic main channel and the crystallization unit, so that protein molecules are continuously diffused into the crystallization unit, so that the protein crystallization speed is fast and the crystal cluster density is high; 2. The protein crystals formed in the crystallization unit are not subject to shear force, and can be extracted and analyzed conveniently; 3. The protein consumption is small, the operation is flexible, and it is suitable for high-pass screening of crystallization conditions; 4. The chip is simple to manufacture and the structure Compact, low cost, and mass-producible.
Owner:武汉介观生物科技有限责任公司

Drug-loaded medical device and preparation method thereof

The present invention relates to the field of medicine technology, in particular to a drug-loaded medical device, comprising a medical device body and at least one drug coating, the drug coating is attached to at least one side of the surface of the medical device body, and The main components of the drug coating include macrolide drugs, the drug coating includes long columnar crystals with more than three ribs, and / or the drug coating includes long columnar crystals with more than three ribs Crystal clusters formed by crystals, the aspect ratio of the long columnar crystals is (1-40):1. The drug-loaded medical device can effectively improve the transfer of the drug to the blood vessel wall and prolong the concentration of the drug in the tissue.
Owner:SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD

Preparation method of high-silicon ZSM-5 molecular sieve with mesoporous structure

The embodiment of the invention provides a preparation method of a high-silicon ZSM-5 molecular sieve with a mesoporous structure, and belongs to the technical field of molecular sieve preparation. The preparation method comprises the following steps: dissolving tetrapropylammonium bromide in water, gradually adding a silicon source at a certain temperature, placing the mixture in an ultrasonic device for ultrasonic treatment for 2-3 hours, and filtering to obtain a pure silicon ZSM-5 crystal cluster; the preparation method comprises the following steps: fully mixing an organic pore-enlarging agent, an inorganic pore-enlarging agent, ZSM-5 crystal clusters and water, adding sodium hydroxide to adjust the pH value to 9-11, simultaneously adding an aluminum source and a silicon source in a stirring state, and stirring for a period of time at a certain temperature; filling the crystallization liquid into a crystallization kettle, crystallizing for a certain time at a certain temperature, filtering, washing, drying and roasting to obtain the high-silicon ZSM-5 molecular sieve. The microporous molecular sieve is subjected to chambering modification and the hydrophobic property of the molecular sieve is improved, so that the adsorption capacity of the molecular sieve on macromolecular organic matters is improved.
Owner:山东亮剑环保新材料有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products